Pertussis vaccine side effects

Written by Li Jian Wu
Pulmonology
Updated on November 06, 2024
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In clinical practice, the pertussis vaccine commonly used is mostly the DTP (Diphtheria, Tetanus, and Pertussis) vaccine, which primarily includes diphtheria, pertussis (whooping cough), and tetanus. This vaccine effectively prevents these three infectious diseases. Common adverse reactions and side effects from the vaccine injection include local muscle site reactions such as redness, swelling, and hard lumps; if there is a secondary bacterial infection, it may also lead to purulent discharge. Additionally, some patients may experience transient fever symptoms, generally not lasting more than twenty-four hours, followed by common gastrointestinal reactions.

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Written by Li Jian Wu
Pulmonology
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What are the symptoms of pertussis encephalopathy?

Pertussis encephalopathy typically presents with persistent high fever, projectile vomiting, nausea, and severe headaches, which are indicators of increased intracranial pressure. It is necessary to conduct timely auxiliary examinations such as cerebrospinal fluid tests and cranial MRI for diagnosis. In conjunction with clinical symptoms, medications to alleviate cerebral edema and reduce intracranial pressure should be chosen for symptomatic treatment. Typically, corticosteroids are needed during the acute phase, along with mannitol, sedatives, and other symptomatic treatments. Additionally, antibiotics should be used to eliminate the Bordetella pertussis bacterium, the pathogen responsible for the condition.

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whooping cough symptoms

Whooping cough is a common respiratory infectious disease, mainly caused by infection with Bordetella pertussis. Typical symptoms include colds, runny nose, etc., and feature paroxysmal coughing. The main characteristic is paroxysmal, spasmodic coughing that occurs in strings, with more than ten or even dozens of coughs at a time. The coughing increases abdominal pressure, leading to nausea and vomiting. Infants and young children may also experience a barking cough and wheezing. Some may also experience symptoms such as urinary and fecal incontinence, flushed face, runny nose, teary eyes, and cyanosis of the lips. Once diagnosed, it is important to promptly select sensitive antibiotics for anti-inflammatory treatment. Currently, the main approach to managing this disease is prevention, including timely vaccination against whooping cough.

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Written by Li Jian Wu
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How is whooping cough transmitted?

Pertussis, commonly known as whooping cough, is primarily caused by the infection of Bordetella pertussis. The main transmission routes are through the respiratory tract or via close contact, particularly in classrooms where young children are present, which can easily lead to cross-infection. The disease has an incubation period of about three to seven days, and in some cases, it can range from two to three weeks. Children under the age of five have the highest incidence rate. Clinically, vaccination is recommended for prevention. Once infected, the early stages of the disease resemble those of a common cold, with typical symptoms being paroxysmal, spasmodic coughing.

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Is the pertussis vaccine an inactivated vaccine?

The pertussis vaccine is not an inactivated vaccine but a live attenuated vaccine, which primarily stimulates the body to produce antibodies. Once antibodies are produced, it can effectively prevent the disease pertussis. The commonly used pertussis vaccine in clinical settings is the trivalent vaccine, also known as the DTP vaccine, which can prevent pertussis, diphtheria, and tetanus—three infectious diseases caused by pathogens. It is essential to follow medical advice and complete the vaccination schedule as prescribed to achieve prevention. After vaccination, it is crucial to observe for any complications or adverse reactions.

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Written by Li Jian Wu
Pulmonology
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Is nebulization useful for pertussis?

Nebulized inhalation for localized treatment of pertussis can be quite effective. It helps alleviate bronchial smooth muscle spasms and is used for spasmodic coughs, effectively easing cough symptoms as a symptomatic treatment measure. However, it is also necessary to target the infectious pathogens with oral or intravenous macrolide antibiotics for anti-inflammatory treatment. Drinking plenty of water, maintaining suitable indoor temperature and humidity, and having confidence in overcoming the disease are important. Although the course of the disease may be long, complete recovery is possible through proper treatment, so there is no need for excessive worry.