How can precocious puberty be treated? Is it reversible?

Written by Quan Xiang Mei
Pediatrics
Updated on September 01, 2024
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Precocious puberty has many causes, including genetic factors, conditions during the mother's pregnancy, or congenital pituitary abnormalities, all of which can lead to the condition. When precocious puberty occurs, it is necessary to conduct diagnostic tests including MRI of the pituitary in the head, bone age assessment, ultrasonography of the gonads, and blood hormone level measurements to determine the appropriate treatment. Mild cases can be managed through a balanced diet, appropriate exercise, and rest. In some cases, oral Chinese medicine can be used if blood hormone levels are not severe enough to require other treatments, to help control the child’s sexual development. In severe cases, such as when a child's bone age is more than one year above their actual age, accompanied by abnormal blood hormone levels and changes in gonadal ultrasound, and significant loss in height, it may be necessary to administer injections of gonadotropin-releasing hormone analogs to control the level of sexual development. If there is a significant loss in height, it may also be necessary to combine this with growth hormone injections to treat growth.

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Written by Dong Xian Yan
Pediatrics
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The precocious puberty stimulation test is used to check for what?

The precocious puberty stimulation test, also known as the luteinizing hormone-releasing hormone stimulation test. The method of examination involves administering an intravenous injection of gonadotropin-releasing hormone, followed by taking blood samples before the injection, and at 30, 60, 90, and 120 minutes after the injection. Serum levels of luteinizing hormone and follicle-stimulating hormone are measured to assess their peak values. This can diagnose whether the gonadal axis has been activated and is a reliable method for diagnosing precocious puberty.

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Written by Zeng Hai Jiang
Pediatrics
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What should I do if precocious puberty is not treated in time?

Precocious puberty is defined as the abnormal condition where secondary sexual characteristics develop before the age of eight in girls and nine in boys. The harm of this disease includes shorter adult height, earlier sexual behavior, and suppressed personality, among other effects. The principle of treatment primarily focuses on improving the child's adult height, with treatments mainly including medication and etiological treatment. If diagnosed and treated early, the prognosis is generally good, and the final adult height can be significantly improved. If treatment is not administered in a timely manner, and the epiphyses of the bones have closed, it may not be possible to alter the final height.

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Written by Quan Xiang Mei
Pediatrics
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How can precocious children reduce estrogen levels?

Once children are diagnosed with precocious puberty, which usually refers to girls developing breasts before the age of 8 and boys showing signs of secondary sexual characteristics such as increased testicular volume and penile thickening before the age of 9, the method to reduce estrogen depends on the severity of the precocious puberty. This includes whether it affects the child's height and the maturity level of the sexual organs, as well as taking into account the estrogen levels at the time of examination for treatment. Mild cases usually do not require medication and can be addressed through dietary and exercise interventions. For moderate cases where hormone levels in the blood have not reached a severe state and there is some loss of height but not to the extent that requires treatment through injections, oral Chinese medicine can be used to reduce estrogen levels. In severe cases, where there is significant change in height, sexual organs, and high hormone levels in the blood, medication such as gonadotropin-releasing hormone analogs can be used to control the child’s sexual development.

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Written by Quan Xiang Mei
Pediatrics
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Premature breast pain has now stopped hurting, does that mean it's healed?

When girls develop breasts before the age of eight, they may experience pain at the breast bud nodules. Pain does not necessarily mean recovery; it is possible that as the breast bud enlarges, the pain will naturally disappear. Whether treatment is needed once precocious puberty occurs and whether it has reached a level of cure mainly depends on the assessment through pediatric bone age, gonadal ultrasound examinations, or a combination of brain pituitary MRI and blood hormone levels to analyze the severity of the condition. For mild cases, with appropriate medication, diet, and exercise guidance, children can reach a basic level of clinical cure. Severe cases require the control of the child's sexual development through the injection of gonadal hormones or hormone-releasing analogues. Psychological impacts due to early sexual development may also necessitate behavioral and psychological interventions.

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Written by Quan Xiang Mei
Pediatrics
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What foods can help recover from precocious puberty?

No specific food can cure the condition of precocious puberty, but it is important to avoid consuming foods high in estrogenic effects, such as dairy products, soy products, and honey, which need to be strictly controlled. Excessive intake can worsen the symptoms of precocious puberty. This includes avoiding fried foods, snacks, certain fruits, and other snacks. In everyday life, it is best to consume seasonal fruits and vegetables and maintain a balanced diet with moderate amounts of meat and eggs, which is beneficial for stabilizing hormone levels associated with precocious puberty.