How can precocious puberty be treated? Is it reversible?

Written by Quan Xiang Mei
Pediatrics
Updated on September 01, 2024
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Precocious puberty has many causes, including genetic factors, conditions during the mother's pregnancy, or congenital pituitary abnormalities, all of which can lead to the condition. When precocious puberty occurs, it is necessary to conduct diagnostic tests including MRI of the pituitary in the head, bone age assessment, ultrasonography of the gonads, and blood hormone level measurements to determine the appropriate treatment. Mild cases can be managed through a balanced diet, appropriate exercise, and rest. In some cases, oral Chinese medicine can be used if blood hormone levels are not severe enough to require other treatments, to help control the child’s sexual development. In severe cases, such as when a child's bone age is more than one year above their actual age, accompanied by abnormal blood hormone levels and changes in gonadal ultrasound, and significant loss in height, it may be necessary to administer injections of gonadotropin-releasing hormone analogs to control the level of sexual development. If there is a significant loss in height, it may also be necessary to combine this with growth hormone injections to treat growth.

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Written by Quan Xiang Mei
Pediatrics
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Where is precocious puberty manifested?

Precocious puberty is primarily characterized by the development of breasts in girls before the age of 8, which leads to a diagnosis of precocious puberty. In boys, an increase in testicular volume and thickening of the penis before the age of 9 or 9.5 years also constitutes a diagnosis of precocious puberty. Once children show signs of precocious puberty, it is crucial to promptly take them to a hospital for the following relevant examinations to determine whether the condition is affecting the child's physical and psychological health. 1. An examination of bone age to determine if it impacts the child's height; 2. An ultrasound of the gonads to verify the severity of sexual development; 3. Under the detailed examination of a doctor, observe whether it affects the child's psychology, thereby providing further reasonable treatment based on the actual manifestations of the child.

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Written by Zeng Hai Jiang
Pediatrics
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Does a hard lump in a child's breast mean precocious puberty?

Children's breasts have lumps, and it is indeed necessary to consider whether it is precocious puberty, but there are other conditions that can cause lumps in children's breasts. For example, cysts or other solid occupying lesions. Besides the development of secondary sexual characteristics, including the development of breasts, growth of axillary hair, and even menstruation in girls, if these secondary sexual characteristics appear before the age of nine and are accompanied by a recent rapid growth in height, then we need to consider the possibility of precocious puberty.

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Written by Yan Xin Liang
Pediatrics
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What should I do if I find out my child is maturing early?

Interventional treatment for precocious puberty varies according to different causes. In principle, once diagnosed with central precocious puberty, aggressive pharmacological treatment is recommended, using inhibitory hormones to suppress development to pre-pubertal levels and inhibit further development of the ovaries and uterus. For peripheral precocious puberty or pseudoprecocious puberty, the cause must be removed. Clinically, if a child accidentally ingests their mother's contraceptive pills causing transient vaginal bleeding, it is essential to carefully inquire about the medical history, thoroughly understand the cause, and determine the treatment method. Also, ask if there has been any special dietary intake recently, including foods or drinks high in estrogen, and if so, remove the cause for treatment.

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Written by Quan Xiang Mei
Pediatrics
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Premature breast pain has now stopped hurting, does that mean it's healed?

When girls develop breasts before the age of eight, they may experience pain at the breast bud nodules. Pain does not necessarily mean recovery; it is possible that as the breast bud enlarges, the pain will naturally disappear. Whether treatment is needed once precocious puberty occurs and whether it has reached a level of cure mainly depends on the assessment through pediatric bone age, gonadal ultrasound examinations, or a combination of brain pituitary MRI and blood hormone levels to analyze the severity of the condition. For mild cases, with appropriate medication, diet, and exercise guidance, children can reach a basic level of clinical cure. Severe cases require the control of the child's sexual development through the injection of gonadal hormones or hormone-releasing analogues. Psychological impacts due to early sexual development may also necessitate behavioral and psychological interventions.

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Written by Zeng Hai Jiang
Pediatrics
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What should I do if precocious puberty is not treated in time?

Precocious puberty is defined as the abnormal condition where secondary sexual characteristics develop before the age of eight in girls and nine in boys. The harm of this disease includes shorter adult height, earlier sexual behavior, and suppressed personality, among other effects. The principle of treatment primarily focuses on improving the child's adult height, with treatments mainly including medication and etiological treatment. If diagnosed and treated early, the prognosis is generally good, and the final adult height can be significantly improved. If treatment is not administered in a timely manner, and the epiphyses of the bones have closed, it may not be possible to alter the final height.