The precocious puberty stimulation test is used to check for what?

Written by Dong Xian Yan
Pediatrics
Updated on September 12, 2024
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The precocious puberty stimulation test, also known as the luteinizing hormone-releasing hormone stimulation test. The method of examination involves administering an intravenous injection of gonadotropin-releasing hormone, followed by taking blood samples before the injection, and at 30, 60, 90, and 120 minutes after the injection. Serum levels of luteinizing hormone and follicle-stimulating hormone are measured to assess their peak values. This can diagnose whether the gonadal axis has been activated and is a reliable method for diagnosing precocious puberty.

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Written by Quan Xiang Mei
Pediatrics
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Can precocious puberty be inherited by children?

Precocious puberty may have a hereditary factor, but it is not very typical. This means that if the parents experienced early puberty or development, their children might also potentially display early signs of puberty or development, but it is not a certainty. Children with precocious puberty typically refer to those who undergo sexual development too early, which can affect their height or their sexual development. This usually impacts their adult height. If parents show signs of early puberty or development, we need to closely monitor the sexual development of their children, observing the development of the nipples in girls and the development of the testicles and penis in boys.

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Written by Dong Xian Yan
Pediatrics
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The difference between precocious puberty and early development

It is generally believed that the development of breasts before the age of eight in girls, and the onset of menstruation before the age of ten; in boys, the development of testicles before the age of nine, appearance of secondary sexual characteristics, and accompanied by rapid physical development, are referred to as precocious puberty. Early development refers to the situation where, before puberty, not only the sexual organs but also other organs in boys and girls begin to develop simultaneously. Therefore, precocious puberty and early development not only differ in the age of onset but also focus more on whether the sexual organs are developing in coordination with the body's other organs. The differences lie not only in the timing but primarily in whether the development of the sexual organs is coordinated with the development of the body's other organs. If the sexual organs and the body's other organs are not developing in coordination, it indicates precocious puberty. If they are coordinated, and merely occurring earlier than usual in puberty, it is considered early development.

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Written by Quan Xiang Mei
Pediatrics
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How can precocious puberty be treated? Is it reversible?

Precocious puberty has many causes, including genetic factors, conditions during the mother's pregnancy, or congenital pituitary abnormalities, all of which can lead to the condition. When precocious puberty occurs, it is necessary to conduct diagnostic tests including MRI of the pituitary in the head, bone age assessment, ultrasonography of the gonads, and blood hormone level measurements to determine the appropriate treatment. Mild cases can be managed through a balanced diet, appropriate exercise, and rest. In some cases, oral Chinese medicine can be used if blood hormone levels are not severe enough to require other treatments, to help control the child’s sexual development. In severe cases, such as when a child's bone age is more than one year above their actual age, accompanied by abnormal blood hormone levels and changes in gonadal ultrasound, and significant loss in height, it may be necessary to administer injections of gonadotropin-releasing hormone analogs to control the level of sexual development. If there is a significant loss in height, it may also be necessary to combine this with growth hormone injections to treat growth.

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Written by Zeng Hai Jiang
Pediatrics
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Can you grow taller after treatment for precocious puberty?

Precocious puberty, if identified and treated early, can allow for normal height growth. Precocious puberty refers to an abnormal condition where secondary sexual characteristics develop in girls before the age of eight and in boys before the age of nine. Based on the mechanism of onset and clinical presentation, it can be categorized into central precocious puberty and peripheral precocious puberty. The main risks of precocious puberty include shorter adult height, earlier sexual behavior, suppressed personality, and more. The primary goal of treatment is to improve the adult height of the affected child. Early detection and prompt treatment are crucial for improving the prognosis of children with precocious puberty. In addition to daily observations for signs of secondary sexual characteristics, it is also important to monitor for any sudden growth spurts in children under the age of ten.

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Written by Quan Xiang Mei
Pediatrics
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How can precocious children reduce estrogen levels?

Once children are diagnosed with precocious puberty, which usually refers to girls developing breasts before the age of 8 and boys showing signs of secondary sexual characteristics such as increased testicular volume and penile thickening before the age of 9, the method to reduce estrogen depends on the severity of the precocious puberty. This includes whether it affects the child's height and the maturity level of the sexual organs, as well as taking into account the estrogen levels at the time of examination for treatment. Mild cases usually do not require medication and can be addressed through dietary and exercise interventions. For moderate cases where hormone levels in the blood have not reached a severe state and there is some loss of height but not to the extent that requires treatment through injections, oral Chinese medicine can be used to reduce estrogen levels. In severe cases, where there is significant change in height, sexual organs, and high hormone levels in the blood, medication such as gonadotropin-releasing hormone analogs can be used to control the child’s sexual development.