Will the platelet count be low in the early stages of cirrhosis?

Written by Wu Hai Wu

Gastroenterology

Updated on January 08, 2025

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The early stage of cirrhosis does not cause a decrease in platelets. Patients in the early stages of cirrhosis often have no obvious symptoms and may only exhibit fatigue, weight loss, jaundice, etc. However, once a patient with cirrhosis develops splenic hyperfunction, it can easily lead to a decrease in platelets, where the platelet count may drop to 100,000 per microliter. In such cases, it might be necessary to perform procedures like splenic embolization or splenectomy for antimicrobial treatment, and it is also important to prevent other complications of cirrhosis, such as esophageal and gastric varices, etc.

Other Voices

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Written by Huang Gang

Gastroenterology

51sec

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What should I do about 7 episodes of gastrointestinal bleeding due to cirrhosis?

There are manifestations of cirrhosis, and it is accompanied by upper gastrointestinal bleeding, which occurs frequently. At this time, a gastroscopy should be conducted, in combination with an ultrasound examination of the liver, to determine whether portal hypertension is causing the bleeding. If the condition is serious, surgical treatment, such as disconnection or shunting, may be needed to relieve the pressure on the portal vein and mitigate the bleeding. Alternatively, vascular ligation can also be performed under gastroscopy to ligate the ruptured vessels, which can also stop the bleeding. Otherwise, long-term repeated heavy bleeding can easily lead to hemorrhagic anemia, and in severe cases, it can cause hemorrhagic shock, posing a life-threatening risk.

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Written by Si Li Li

Gastroenterology

47sec

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What are the complications of late-stage liver cirrhosis?

Late-stage cirrhosis can lead to many complications, such as bleeding from esophageal and gastric varices, which is one of the more common and severe complications of cirrhosis. Other complications include spontaneous peritonitis, liver cancer, hepatorenal syndrome, hepatic encephalopathy, portal vein thrombosis, and symptoms like ascites, palmar erythema, and spider angiomas. Additionally, there may be symptoms such as dark skin or hyperpigmentation and jaundice. Once cirrhosis is diagnosed, timely intervention and treatment are necessary to delay the progression of the disease.

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Written by Si Li Li

Gastroenterology

52sec

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What are the symptoms of early cirrhosis?

Early-stage cirrhosis does not have specific symptoms, and its manifestations are not typical. Some patients may have no symptoms at all, while others may experience general weakness, aversion to greasy food, nausea, vomiting, poor appetite, abdominal distension, and abdominal pain. If these symptoms occur, it is recommended to visit a hospital promptly for an examination to determine the specific illness. If diagnosed with cirrhosis, it is necessary to identify the cause. Common diseases that lead to cirrhosis include viral hepatitis, such as chronic hepatitis B or chronic hepatitis C, as well as alcoholic liver disease and fatty liver. Once the cause is identified, treatment can be targeted based on the specific cause.

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Written by Yang Chun Guang

Gastroenterology

56sec

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How to treat splenomegaly and liver cirrhosis?

Once liver cirrhosis is detected, accompanied by an enlarged spleen and hyperactive spleen function, this condition can be addressed through interventional methods to resolve issues of spleen enlargement and hyperfunction. This reduces the destruction of red blood cells, white blood cells, and platelets. The interventional approach primarily involves sterile necrosis and absorption of the spleen, thus resolving spleen issues. As for treating liver cirrhosis, it is primarily important to understand the causes of the cirrhosis. If the cirrhosis is caused by a virus, antiviral treatment is needed. There are corresponding antiviral medications for cirrhosis caused by hepatitis B and C. If the cirrhosis is caused by alcohol, it is essential to abstain from alcohol as part of the treatment. In addition, medications that combat liver cirrhosis should be used.

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Written by Si Li Li

Gastroenterology

1min 8sec

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Can severe cirrhosis be cured?

Severe cirrhosis is understood to refer to the decompensated stage of cirrhosis, which is the later stage of the condition, primarily characterized by the hardening of the liver. Additionally, it presents a series of bodily complications such as ascites, as well as esophageal and gastric varices caused by portal hypertension. Sometimes, because of these varices, accidental rupture can occur during eating, leading to severe bleeding, which is a major upper gastrointestinal hemorrhage — a very dangerous complication. If this bleeding is not controlled, it can become life-threatening. Moreover, the skin may display spider nevi, and palmar erythema can appear on the hands; these are common manifestations and complications during the decompensated phase of cirrhosis. Thus, cirrhosis is not curable. Treatment focuses on symptomatic relief to minimize discomfort caused by the symptoms, but the disease itself cannot be cured.