What are the complications of late-stage liver cirrhosis?

Written by Si Li Li
Gastroenterology
Updated on November 08, 2024
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Late-stage cirrhosis can lead to many complications, such as bleeding from esophageal and gastric varices, which is one of the more common and severe complications of cirrhosis. Other complications include spontaneous peritonitis, liver cancer, hepatorenal syndrome, hepatic encephalopathy, portal vein thrombosis, and symptoms like ascites, palmar erythema, and spider angiomas. Additionally, there may be symptoms such as dark skin or hyperpigmentation and jaundice. Once cirrhosis is diagnosed, timely intervention and treatment are necessary to delay the progression of the disease.

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Written by Li Qiang
Intensive Care Unit
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Which is more serious, liver failure or cirrhosis?

Liver failure refers to a functional impairment of the liver, which could be acute or chronic damage. For instance, it could be the end stage of chronic liver disease, or an acute condition such as hepatitis, or another acute liver lesion. Other common lesions may also cause a sudden abnormality in liver function, resulting in severe liver dysfunction. At this point, liver cirrhosis is a common cause of liver failure. For example, in the middle and late stages of liver cirrhosis, liver function is completely decompensated, meaning the liver can no longer maintain its basic normal functions, leading to liver failure. Therefore, liver failure is one of the major consequences of liver cirrhosis, but the two are distinct. Liver failure can also be caused by other reasons not related to cirrhosis. For example, acute ischemia in the liver, such as in shock patients, can lead to liver ischemia and subsequently liver failure. Liver cirrhosis is just one of the common causes thereof.

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Written by Wu Hai Wu
Gastroenterology
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Do people with cirrhosis and their family members need to use separate bowls and chopsticks when eating?

Patients with cirrhosis and their family members do not necessarily have to use separate bowls and chopsticks when eating. The causes of cirrhosis include infectious and non-infectious cirrhosis. Among infectious cirrhosis, some are transmitted through blood and others through fecal-oral transmission. Only diseases transmitted via the fecal-oral route require separate bowls and chopsticks, such as hepatitis A and hepatitis E. These types require separation from family members during meals. However, hepatitis B, or some non-infectious types such as alcoholic hepatitis, do not require the use of separate eating utensils.

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Written by Wu Hai Wu
Gastroenterology
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What should I do if cirrhosis causes general weakness?

Liver cirrhosis can lead to general weakness due to electrolyte disorders or severe liver function impairment, causing the symptoms mentioned above. Once general weakness occurs, it is necessary to go to the hospital for comprehensive auxiliary examinations, such as liver function tests, routine blood tests, and electrolyte tests. Additionally, imaging studies of the abdomen should be performed to determine whether conditions like ascites, anemia, or hyponatremia exist. Different treatments are administered based on different disease diagnoses. For instance, if the weakness is due to severe ascites causing dilutional hyponatremia, sodium supplementation might be necessary, along with appropriate ascites drainage.

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Written by Shen Jiang Chao
Radiology
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Can cirrhosis be detected by a CT scan?

Cirrhosis can be detected by a CT scan. Early-stage cirrhosis has no specific diagnostic value on CT, but middle to late-stage cirrhosis typically manifests as wavy changes in the liver capsule, enlarged liver lobes, and disproportionate size of liver lobes, with most changes involving an enlargement of the left lobe and caudate lobe and a relative shrinkage of the right lobe. Additionally, secondary manifestations of cirrhosis, such as portal hypertension, can cause enlargement of the spleen and varices in the lower esophagus and stomach fundus. When cirrhosis is detected, it is advisable to perform an enhanced CT scan to determine the potential for malignant transformation in liver regenerative nodules.

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Written by Wu Hai Wu
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Is it serious if someone with cirrhosis doesn't have bowel movements?

Cirrhosis without bowel movements does not necessarily mean that the condition is very severe. Patients with cirrhosis who have no bowel movements might be experiencing poor digestion, leading to slow intestinal movements and subsequently constipation. However, constipation can potentially trigger hepatic encephalopathy, thus it requires proactive treatment. Oral lactulose can be used for bowel movement, or an enema with white vinegar to acidify the intestines can also be administered. Patients with cirrhosis who develop hepatic encephalopathy, upper gastrointestinal bleeding, or primary peritonitis are experiencing severe conditions and need to actively undergo corresponding treatment measures. (Please use medications under the guidance of a doctor.)