Can severe cirrhosis be cured?

Written by Si Li Li
Gastroenterology
Updated on December 11, 2024
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Severe cirrhosis is understood to refer to the decompensated stage of cirrhosis, which is the later stage of the condition, primarily characterized by the hardening of the liver.

Additionally, it presents a series of bodily complications such as ascites, as well as esophageal and gastric varices caused by portal hypertension. Sometimes, because of these varices, accidental rupture can occur during eating, leading to severe bleeding, which is a major upper gastrointestinal hemorrhage — a very dangerous complication. If this bleeding is not controlled, it can become life-threatening. Moreover, the skin may display spider nevi, and palmar erythema can appear on the hands; these are common manifestations and complications during the decompensated phase of cirrhosis.

Thus, cirrhosis is not curable. Treatment focuses on symptomatic relief to minimize discomfort caused by the symptoms, but the disease itself cannot be cured.

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Written by Si Li Li
Gastroenterology
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What are the symptoms of early cirrhosis?

Early-stage cirrhosis does not have specific symptoms, and its manifestations are not typical. Some patients may have no symptoms at all, while others may experience general weakness, aversion to greasy food, nausea, vomiting, poor appetite, abdominal distension, and abdominal pain. If these symptoms occur, it is recommended to visit a hospital promptly for an examination to determine the specific illness. If diagnosed with cirrhosis, it is necessary to identify the cause. Common diseases that lead to cirrhosis include viral hepatitis, such as chronic hepatitis B or chronic hepatitis C, as well as alcoholic liver disease and fatty liver. Once the cause is identified, treatment can be targeted based on the specific cause.

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Written by Ye Xi Yong
Infectious Diseases
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Can cirrhosis caused by hepatitis B virus be cured?

Hepatitis B virus-induced cirrhosis was previously considered incurable, though its progression could be slowed. However, recent observations and studies have shown that a small fraction of patients with early-stage hepatitis B virus-induced cirrhosis can be cured. However, the proportion of these patients is extremely low. To draw an analogy, cirrhosis is like our houses. If the cement, steel bars, and brick structure are damaged, then the house is difficult to repair. Cirrhosis is akin to the structural damage of the house, making it hard to recover.

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Written by Huang Gang
Gastroenterology
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The difference between fatty liver and liver cirrhosis

Fatty liver is shown through ultrasound as having an increased and finely detailed echo in the liver, which is completely different from liver cirrhosis. Liver cirrhosis is generally caused by the progression of chronic hepatitis, commonly seen in hepatitis B-related cirrhosis, hepatitis C-related cirrhosis, and alcoholic cirrhosis. Cirrhosis resulting from drug-induced liver damage or from severe fatty liver is relatively rare in clinical practice. Therefore, we should not panic. Once diagnosed with fatty liver, it can be reversed through proper diet and reasonable exercise, and its progression to liver cirrhosis can be prevented. So, everyone, there is no need to rush or panic.

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Written by Wu Hai Wu
Gastroenterology
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Is the pain obvious in the early stages of cirrhosis?

In the early stages of cirrhosis, the pain is not very obvious. Patients in the early stages of cirrhosis may experience vague discomfort in the upper right abdomen, while others may never experience pain at all. Those in the early stages may also have symptoms such as belching, fatigue, acid reflux, jaundice, and dark urine. Further comprehensive auxiliary examinations are needed, such as liver function tests and abdominal imaging studies. At the same time, it is important to identify the cause of early-stage cirrhosis in patients as soon as possible and adopt appropriate treatment measures based on different causes. For instance, if it is caused by alcohol, then treatment should involve abstaining from alcohol.

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Written by Huang Gang
Gastroenterology
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Can second stage cirrhosis be cured?

No form of cirrhosis can be cured, but it is possible to alleviate the condition, control it, and slow its progression through medication. Therefore, once diagnosed with cirrhosis, it is essential to understand the type of cirrhosis, which means making an accurate diagnosis. If it is hepatitis B or C related cirrhosis, active antiviral medication should be taken orally to quickly control and slow the progression of the disease; for alcoholic liver, it is advised to abstain from alcohol strictly; if the condition is severe and irreversible, liver transplant surgery could be considered.