Can severe cirrhosis be cured?

Written by Si Li Li
Gastroenterology
Updated on December 11, 2024
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Severe cirrhosis is understood to refer to the decompensated stage of cirrhosis, which is the later stage of the condition, primarily characterized by the hardening of the liver.

Additionally, it presents a series of bodily complications such as ascites, as well as esophageal and gastric varices caused by portal hypertension. Sometimes, because of these varices, accidental rupture can occur during eating, leading to severe bleeding, which is a major upper gastrointestinal hemorrhage — a very dangerous complication. If this bleeding is not controlled, it can become life-threatening. Moreover, the skin may display spider nevi, and palmar erythema can appear on the hands; these are common manifestations and complications during the decompensated phase of cirrhosis.

Thus, cirrhosis is not curable. Treatment focuses on symptomatic relief to minimize discomfort caused by the symptoms, but the disease itself cannot be cured.

Other Voices

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Written by Li Hu Chen
Imaging Center
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Can cirrhosis be detected by ultrasound B?

If there are signs of hardening in the liver, which we call cirrhosis, an ultrasound, specifically a hepatobiliary ultrasound, can detect it. Especially in the middle and late stages, cirrhosis has some characteristic features on an ultrasound. First, one can observe the size of the liver. By the middle and late stages, the liver usually shrinks—a slight enlargement may occur early on, but it generally progressively diminishes. Additionally, the texture of the liver becomes harder, and through the ultrasound, the texture appears uneven with a bumpy feeling, or in other words, there can be seen a diffuse and uneven echo. However, for early-stage cirrhosis, a standard ultrasound may not be as sensitive. Nowadays, there are digital liver ultrasounds specifically designed to measure the degree of liver hardness, which provide objective data to help diagnose more sensitively and objectively. This method can definitely detect the condition.

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Written by Wu Hai Wu
Gastroenterology
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Why does cirrhosis cause increasing weight loss and what can be done about it?

The reason why patients with cirrhosis are becoming thinner might be due to the decreased protein synthesis function of the liver after cirrhosis, leading to progressively lesser protein in the body, which results in the patient becoming thinner. It could also be because cirrhosis leads to poor digestion and absorption in patients, thereby reducing their absorption capacity and causing them to lose weight. Under these circumstances, some medications can be used for treatment, such as the infusion of albumin to supplement plasma proteins in the body. It is also important to actively treat the underlying cause of cirrhosis. For example, in the case of alcoholic cirrhosis, active efforts to abstain from alcohol and rehabilitative treatment are necessary. If the cirrhosis is caused by chronic hepatitis B virus infection, antiviral treatment should be administered.

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Written by Zhang Jian Kang
Infectious Disease
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Can you have intercourse after hepatic cirrhosis caused by hepatitis B?

Liver cirrhosis caused by hepatitis B, if not treated with standard antiviral therapy, is very likely to test positive for the hepatitis B virus. HBV-DNA is a good indicator of the hepatitis B virus; if HBV-DNA tests positive, then it is contagious. The main transmission routes of hepatitis B include mother-to-child transmission, blood and body fluid transmission, and sexual transmission between spouses, though this route carries a relatively lower risk. Why is this the case? Firstly, the spouse may already have hepatitis B surface antibodies, which are protective antibodies providing immunity against hepatitis B. Secondly, when adults are infected with hepatitis B, most can acutely clear the virus, preventing the chronic manifestation of the disease.

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Written by Yang Chun Guang
Gastroenterology
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Is liver cirrhosis with ascites contagious?

Liver cirrhosis in the decompensated stage with ascites present is not inherently contagious. Whether the condition is infectious depends not on the severity of liver function, the degree of liver cirrhosis, or the gravity of ascites, but rather on the underlying cause of the liver cirrhosis. For example, liver cirrhosis caused by alcohol consumption is not contagious. However, if the liver cirrhosis is due to viral hepatitis, such as commonly seen with hepatitis B or C, the condition can be infectious. Therefore, the presence of ascites or liver cirrhosis itself is not an indicator of infectiousness; the crucial factor is whether there is an infectious virus present.

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Written by Si Li Li
Gastroenterology
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What are the complications of late-stage liver cirrhosis?

Late-stage cirrhosis can lead to many complications, such as bleeding from esophageal and gastric varices, which is one of the more common and severe complications of cirrhosis. Other complications include spontaneous peritonitis, liver cancer, hepatorenal syndrome, hepatic encephalopathy, portal vein thrombosis, and symptoms like ascites, palmar erythema, and spider angiomas. Additionally, there may be symptoms such as dark skin or hyperpigmentation and jaundice. Once cirrhosis is diagnosed, timely intervention and treatment are necessary to delay the progression of the disease.