Classification of the Causes of Infertility

Written by Wang Jing Hua
Obstetrics and Gynecology
Updated on December 25, 2024
00:00
00:00

For infertility, it is important to conduct relevant tests as early as possible while young, to receive effective treatment promptly, and to complete childbirth at the earliest. Firstly, male testing should be conducted because the probability of male infertility is also high, and the tests for males are relatively simpler. Afterwards, the causes in females should be investigated, such as monitoring ovulation and conducting endocrine tests for ovulation. Then, the condition of the endometrium should be examined, and a hysterosalpingography should be performed between the third and seventh days of a clean menstrual period to see if this factor contributes to infertility. Subsequently, various biochemical tests, such as immune function and pre-thrombotic state, should also be considered.

Other Voices

doctor image
home-news-image
Written by Gan Hai Ying
Obstetrics and Gynecology
1min 3sec home-news-image

Why does premature ovarian failure cause infertility?

The primary reason that premature ovarian failure leads to infertility is due to the decline in ovarian function it causes. Reduced ovarian function results in insufficient secretion of estrogen levels within the body. Consequently, the follicles on the ovaries do not develop and mature, and without mature egg cells, the sperm and egg cannot meet, which leads to infertility. Additionally, women with premature ovarian failure experience low hormone levels that prevent changes in the uterine lining, making it unsuitable for a fertilized egg to implant in the uterine cavity, which also causes infertility. Premature ovarian failure in women often leads to infertility. Therefore, it is difficult for women with this condition to conceive. If childbearing is desired, after treatment to regulate menstruation, it may be necessary to use assisted reproductive technologies such as in vitro fertilization to achieve pregnancy.

doctor image
home-news-image
Written by Shen Li Wen
Obstetrics and Gynecology
1min 12sec home-news-image

What tests are done for secondary infertility?

The most common cause of secondary infertility in women is blocked fallopian tubes. In this case, a hysterosalpingography with iodine oil should be performed to understand the patency of the fallopian tubes and the specific location of the blockage, which can guide future treatment. Additionally, if a woman has abnormal vaginal discharge, a routine gynecological examination should be conducted to check for any cervical lesions. A vaginal secretion test should be performed to see if vaginal inflammation is affecting normal pregnancy. Some women experience infertility after having an abortion or induced abortion, and for these women, it's also worth considering whether uterine issues are causing secondary infertility. A hysteroscopy can be done to investigate this. When a woman experiences secondary infertility, her sexual partner or spouse should also be examined to assess sperm quality and any potential obstacles in the sperm delivery pathway.

doctor image
home-news-image
Written by Zhao Li Li
Obstetrics
48sec home-news-image

Why does adenomyosis cause infertility?

Under normal circumstances, adenomyosis is mainly due to factors such as the elasticity of muscle fibers in the uterine muscle layer, leading to abnormal enlargement of the uterus. This causes severe complications such as increased menstrual flow and painful menstruation. There are no specific treatment methods. During the onset of adenomyosis, it might affect the normal menstrual cycle of women, leading to increased menstrual flow or irregular menstruation. This can easily interfere with the normal development and ovulation of follicles, therefore significantly impacting normal conception. Once diagnosed, it is also necessary to actively treat the symptoms to avoid delaying normal conception.

doctor image
home-news-image
Written by Kang Jian Hua
Reproductive Center
1min 28sec home-news-image

The seven items of infertility are as follows:

In the examination items for infertility, the seven-item infertility tests are often mentioned. These seven tests include: anti-sperm antibody test, anti-endometrial antibody test, anti-zona pellucida antibody test, anti-trophoblast antibody test, anti-chorionic gonadotropin antibody test, anti-zinc ion antibody test, and anti-ovarian antibody test. Each of these tests targets different conditions. The anti-sperm antibody test and anti-endometrial antibody test are mainly used for the auxiliary diagnosis of immunological infertility. The anti-trophoblast antibody test is mainly used for diagnosing recurrent miscarriage. The anti-chorionic antibody test is primarily for the diagnostic examination of threatened miscarriage. The anti-zona pellucida antibody test is used mainly for the auxiliary diagnosis of premature ovarian failure. The anti-ovarian antibody test is used for conditions such as premature ovarian failure, infertility, menstrual disorders, etc. The anti-chorionic antibody test plays a role in the diagnosis of threatened miscarriage, and the anti-zinc ion antibody test is used for recurrent miscarriage and stillbirth and other related diseases.

doctor image
home-news-image
Written by Kang Jian Hua
Reproductive Center
1min 6sec home-news-image

Can immunological infertility be treated?

Immunological infertility is treatable. There are several main methods for treating immunological infertility. The first method is the blocking therapy, which involves using condoms for 3-6 months to make the sperm antigen antibodies disappear, thereby increasing the conception rate through alternate day intercourse. Many women are able to conceive through this method. The second method is in vitro fertilization, which is chosen if there is a high density of antisperm antibodies in the woman's body, making in vitro fertilization necessary for conception. This method generally has a high success rate. The third method is intrauterine artificial insemination. When there are many antisperm antibodies in the woman’s cervical mucus, this method involves treating the male’s semen outside the body, selecting high-quality sperm for artificial insemination. The fourth method is immunosuppressive therapy, which primarily involves the use of corticosteroids. However, the use of these hormones often causes some adverse damage to the body.