How to diagnose infertility

Written by Zhao Min Ying
Reproductive Medicine
Updated on April 17, 2025
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When a couple lives together, has regular sexual intercourse without contraception for over a year, and does not conceive, it is termed infertility. If it concerns the female, it is called infertility, and if it concerns the male, it is called sterility. If a woman has previously been pregnant or has a history of childbirth or pregnancy, it is known as secondary infertility. If she has never been pregnant or had a childbirth, it is considered primary infertility. The same categories apply to males: those with a history of fathering a child, regardless of with which partner, are described as having secondary sterility, whereas those who have never impregnated a woman suffer from primary sterility. To diagnose infertility or sterility, one needs to undergo relevant medical checks at a hospital's reproductive medicine department. These examinations include ovulation monitoring, endocrine tests, gynecological examinations for women, and semen analyses and fallopian tube inspections for men, among others.

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Written by Shen Li Wen
Obstetrics and Gynecology
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Do Nabothian cysts of the cervix cause infertility?

Women with cervical Nabothian cysts will not become infertile because of them. Cervical Nabothian cysts are actually cysts of the cervical glands. Abnormal substances, such as squamous epithelium during the healing process, have entered the gland ducts, blocking them and preventing the contents of the cysts from escaping. They merely indicate the squamo-columnar junction of the cervix and do not affect the cervical canal or cause it to narrow, nor do they affect vaginal secretions or female infertility. However, if a woman has a particularly large single cervical cyst or multiple cervical gland cysts, they may cause cervical hypertrophy. When the cervix is enlarged, there might be hyperplasia in the interstitial part and possible formation of fibrous tissue. This could potentially affect the dilation of the cervix during childbirth.

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Written by Gan Hai Ying
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Why does premature ovarian failure cause infertility?

The primary reason that premature ovarian failure leads to infertility is due to the decline in ovarian function it causes. Reduced ovarian function results in insufficient secretion of estrogen levels within the body. Consequently, the follicles on the ovaries do not develop and mature, and without mature egg cells, the sperm and egg cannot meet, which leads to infertility. Additionally, women with premature ovarian failure experience low hormone levels that prevent changes in the uterine lining, making it unsuitable for a fertilized egg to implant in the uterine cavity, which also causes infertility. Premature ovarian failure in women often leads to infertility. Therefore, it is difficult for women with this condition to conceive. If childbearing is desired, after treatment to regulate menstruation, it may be necessary to use assisted reproductive technologies such as in vitro fertilization to achieve pregnancy.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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Is secondary infertility easy to treat?

If it is infertility, treatment is relatively difficult and generally not easy. First, for secondary infertility, it depends on the cause. If it's due to fallopian tube blockage, the extent of the blockage needs to be considered. If it is because the ovaries do not ovulate, then it is necessary to go to the hospital for endocrine testing. Treatment should be based on the results of the endocrine tests, and only when hormone levels are normal will there be normal ovulation and clear fallopian tubes. Without problems related to immunity, it is possible to properly prepare for pregnancy. Therefore, if it is secondary infertility, it is essential to go to the hospital for infertility-related examinations to identify any abnormalities and treat them accordingly. Both primary and secondary infertility are difficult to treat.

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What are the causes of male infertility?

There are many diseases or factors that can lead to male infertility, leading to azoospermia, severe oligospermia, and oligozoospermia, as well as normospermic infertility, polyspermia, asthenospermia, etc. The main causes can be summarized in the following points: First, male sexual dysfunction, such as erectile dysfunction, premature ejaculation, and anejaculation, can all cause male infertility. Second, abnormalities in sperm structure and seminal plasma can affect sperm motility, capacity, and reaction. Third, obstruction of the vas deferens affects the transport of sperm. Fourth, infection of the reproductive tract. Fifth, endocrine disorders, including deficiencies in gonadotropins. Sixth, chromosomal abnormalities, including the common pseudohermaphroditism chromosome.

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"What does infertility OC mean?"

Infertility OC refers to the ovarian stimulation protocols for in vitro fertilization (IVF), commonly divided into long and short protocols. Ovarian stimulation in IVF is done to obtain more eggs for better results. The choice between protocols is not determined by time, but by assessing the patient’s ovarian function. Patients with good ovarian function use the long protocol, while those with poor ovarian function use the short protocol. Although the long protocol takes more time, it provides better ovulation results and a more consistent ovarian response, preventing premature ovulation. The short protocol, although quicker, often has less effective stimulation results and an inconsistent ovarian response, which frequently leads to premature ovulation. Thus, the long protocol is the standard for ovarian stimulation, while the short protocol is a contingency plan used when there is concern that poor ovarian function might prevent follicle development with the long protocol.