Neurodermatitis is a common chronic inflammatory skin disease characterized by paroxysmal severe itching and lichenoid changes in the skin. Its early symptoms mainly manifest as flat papules the size of pinheads or grains of rice, with a small amount of coagulation on top. These generally are distributed over areas such as the neck, sacral region, elbows, knees, inner thighs, perineum, perianal region, and eyelids. Over time, the rashes may merge into large patches, and the affected skin becomes thickened and rough, accompanied by intense itching.