Neurodermatitis, also known as chronic simple lichen, is a common chronic inflammatory skin disease characterized by episodic severe itching and lichenoid changes in the skin. It is a neurofunctional disorder. The causes of the disease may be related to neuropsychiatric factors, gastrointestinal dysfunction, endocrine disorders, local skin irritation, diet, and other internal and external factors. Clinically, it is generally advised for patients to minimize alcohol consumption, reduce intake of spicy and hot foods, and avoid irritants such as shrimp, crab, and other seafood.