Can Helicobacter pylori tests be done during the pregnancy preparation stage?

Written by Qu Chun Yao
Obstetrics and Gynecology
Updated on January 18, 2025
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During the preconception stage, it is possible to test for Helicobacter pylori, but if testing is to be conducted, breath tests should be avoided. This is because breath tests use carbon-14 or carbon-13, which are radioactive, making them unsuitable for women planning pregnancy.

At this time, it is also important to weigh the pros and cons. If there are chronic gastric or duodenal ulcers, and the symptoms are quite apparent, it is necessary to conduct tests. It is advisable to postpone pregnancy, address the gastrointestinal diseases first, and then proceed with pregnancy. If there are gastric or duodenal diseases at such time, pregnancy could possibly exacerbate the condition.

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Written by Jiang Guo Ming
Gastroenterology
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Do normal people have Helicobacter pylori?

In my understanding, a “normal person” refers to individuals who do not experience any stomach discomfort. In our country, the infection rate of Helicobacter pylori is extremely high, with reports indicating that over 50% of adults are infected, albeit asymptomatically. Thus, it is certain that many so-called "normal people" are infected with Helicobacter pylori, also known as asymptomatic Helicobacter pylori carriers. This condition also requires antibacterial treatment because there is a close relationship between Helicobacter pylori and gastritis, ulcers, and gastric cancer. Even for patients with chronic superficial gastritis, if Helicobacter pylori is present, eradication therapy is advocated. If not completely eradicated, it often leads to the development of chronic atrophic gastritis, which is a more serious condition.

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Written by Jiang Guo Ming
Gastroenterology
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Helicobacter pylori symptoms

Helicobacter pylori itself is just a bacterium, often parasitizing the stomach or oral cavity of the human body. It cannot be said that Helicobacter pylori has symptoms, but rather that symptoms may occur after being infected by Helicobacter pylori. Many normal people infected with Helicobacter pylori may not exhibit any discomfort. However, if Helicobacter pylori causes gastritis or peptic ulcers, etc., related symptoms may appear. For instance, abdominal pain, bloating, belching, acid reflux, and so on; in cases of peptic ulcers, corresponding symptoms, such as periodic, recurrent episodes of upper abdominal pain associated with eating and so forth, may also occur and will need to be determined based on the specific situation.

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Written by Yang Chun Guang
Gastroenterology
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Can a gastroscopy detect Helicobacter pylori?

Helicobacter pylori is a type of bacterium that can easily infect and cause chronic gastritis, and it even has the potential to lead to cancer. Therefore, patients with Helicobacter pylori generally require formal treatment. In terms of diagnostics, Helicobacter pylori can be detected through a gastroscopy, but the bacteria cannot be detected by gastroscopy alone; the test for Helicobacter pylori is performed under the scope. However, the current main method for testing Helicobacter pylori is through a breath test, since undergoing a gastroscopy just to test for the bacteria can be quite uncomfortable. Moreover, the accuracy of the breath test is relatively high, so currently, Helicobacter pylori is generally detected via breath testing rather than gastroscopy.

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Written by Wang Hui Jie
Gastroenterology
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Can a gastroscopy detect Helicobacter pylori?

Since Helicobacter pylori is a type of bacterium, it cannot be seen with the naked eye. However, current research indicates that Helicobacter pylori is strongly associated with certain mucosal appearances under endoscopy. Therefore, endoscopists can infer the presence of an infection based on certain mucosal appearances observed during the procedure. However, if the only purpose is to test for Helicobacter pylori infection without needing a gastroscopy, then we can opt for non-invasive methods such as the carbon-13 urea breath test, carbon-14 urea breath test, stool antigen test, and serological antibody tests, which are commonly used methods of testing. Moreover, after treatment for Helicobacter pylori, it is recommended to use either the carbon-13 or carbon-14 urea breath test for examination.

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Written by Wu Hai Wu
Gastroenterology
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If Helicobacter pylori is not treated properly, will it become more severe?

Helicobacter pylori infection, if not treated properly, does not necessarily become more severe. However, if treatment fails, it is necessary to undergo re-treatment. It is recommended to visit a hospital and consult with a qualified gastroenterologist to adjust the treatment plan. The choice of specific medications, as well as their dosages and usage, should be carried out according to medical advice. During the treatment of Helicobacter pylori infection, it is important to avoid overeating, maintain regular meal times and portions, consume easily digestible foods, and eat plenty of fresh vegetables and fruits rich in vitamins. Spicy and irritating foods should be avoided.