Can a gastroscopy check for Helicobacter pylori?

Written by Yang Chun Guang
Gastroenterology
Updated on September 06, 2024
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Normally, when conducting a gastroscopy, it is possible to test for Helicobacter pylori, but this method of detection is less commonly used in clinical practice nowadays, as it requires undergoing a gastroscopy, which can be quite distressing and may cause nausea and vomiting.

Currently, the main method used in clinical practice for detecting Helicobacter pylori is the breath test, typically using carbon-13 or carbon-14. This involves swallowing a capsule and then blowing into a device to test for Helicobacter pylori infection. This method is more convenient, which is why it has increasingly replaced gastroscopy for detecting Helicobacter pylori.

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Written by Ren Zheng Xin
Gastroenterology
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Which department checks for Helicobacter pylori?

Current research suggests that Helicobacter pylori infection is the primary cause of various gastric diseases. It is best to visit the gastroenterology department of a hospital to check for Helicobacter pylori, where a Carbon-14 breath test can be conducted to determine the amount of Helicobacter pylori in the stomach. If there is a high quantity of bacteria, or if there are gastrointestinal diseases present, one might consider a treatment to eradicate Helicobacter pylori. This generally involves the use of two types of antibiotics along with a gastric mucosal protector or a medication that inhibits stomach acid secretion. It is also important to regularly follow up, maintain a regular diet, and avoid spicy and irritating foods.

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Written by Huang Ya Juan
Gastroenterology
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How to eradicate Helicobacter pylori

The spontaneous clearance rate of Helicobacter pylori infection is extremely low, meaning that it is almost impossible to cure itself. If not treated medically, it may lead to a lifelong infection. Currently, the consensus both domestically and internationally on handling Helicobacter pylori is that eradication requires combination therapy with multiple drugs, categorized into triple therapy and quadruple therapy, with a treatment duration of 2 weeks. Triple therapy consists of a proton pump inhibitor (PPI) plus two antibiotics. We currently use quadruple therapy, which includes two antibiotics, a gastric mucosal protectant, and a proton pump inhibitor. The choice of these drugs is complex. Common anti-inflammatory drugs include amoxicillin, clarithromycin, metronidazole, and levofloxacin; in cases of bacterial resistance, we recommend using furazolidone or tetracycline. Specific medications should be consulted in detail with a doctor. After the treatment course, we need to assess whether the eradication was successful, with a re-examination one month after stopping the drugs. After the eradication of Helicobacter pylori, the rate of reinfection in adults is very low, but the reinfection rate in children is somewhat higher than in adults. Not everyone infected with Helicobacter pylori needs eradication; it is necessary only for those with ulcers, erosion, atrophy, or related symptoms.

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Written by Si Li Li
Gastroenterology
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Does the breath test for Helicobacter pylori require fasting?

Currently, the detection of Helicobacter pylori is highly accurate and specific, and a rapid, simple, and effective method is the Carbon-14 breath test. The Carbon-14 breath test requires no eating within six hours, so it is best to take it on an empty stomach. Therefore, it is preferable to test for Helicobacter pylori on an empty stomach. Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%. Helicobacter pylori is the principal cause of chronic gastritis, peptic ulcers, or gastric cancer. Therefore, if symptoms of the digestive system occur, such as belching, acid reflux, upper abdominal pain, nausea, and poor appetite, it is advisable to conduct a test for Helicobacter pylori, specifically the Carbon-14 breath test, to confirm the infection of Helicobacter pylori.

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Written by Wu Hai Wu
Gastroenterology
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Do you need to change your toothbrush when treating Helicobacter pylori?

It is recommended to change your toothbrush during the treatment period for Helicobacter pylori. This is because Helicobacter pylori exists not only in the stomach but can also be detected in the saliva, dental plaque, and tongue coating of the mouth. Once infected with Helicobacter pylori, a two-week quad therapy that includes bismuth agents is necessary to eradicate the infection. After eradication, the bacteria might still be present on the toothbrush, which could lead to a recurring infection. Therefore, it is advised that patients change their toothbrush after undergoing treatment for Helicobacter pylori. Patients infected with Helicobacter pylori should undergo the two-week quad therapy including bismuth agents for treatment.

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Written by Wu Hai Wu
Gastroenterology
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Is Helicobacter pylori a serious illness?

Helicobacter pylori is not a major disease, so patients do not need to be overly anxious and worried. Once an infection of Helicobacter pylori is detected, patients can consider visiting the gastroenterology department of a formal hospital. The choice of medication should be based on the doctor's experience. Also, the use and dosage of the medication should be followed according to the doctor's instructions. For the treatment of Helicobacter pylori infections, it is recommended to use a bismuth-containing quadruple therapy for two weeks to eradicate the infection. During the treatment period, it is advisable to avoid eating spicy and irritating foods, and also to avoid alcohol, strong tea, coffee, etc. Avoid overeating and eat small, easily digestible meals more frequently. (Please follow the doctor’s prescription when using medication.)