What causes constrictive pericarditis?

Written by Han Shun Li
Pulmonology
Updated on September 05, 2024
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Constrictive pericarditis refers to the fibrosis or calcification of the pericardium, which restricts the filling of the ventricles during diastole and leads to a series of symptoms. What causes constrictive pericarditis? Generally, constrictive pericarditis is secondary to acute pericarditis. In our country, the most common cause of constrictive pericarditis is tuberculous pericarditis, followed by purulent or traumatic pericarditis. A minority of constrictive pericarditis cases may be associated with tumors of the pericardium, acute nonspecific pericarditis, and radiation-induced pericarditis, among others. Of course, some patients have idiopathic constrictive pericarditis.

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acute pericarditis clinical manifestations

The clinical manifestations of acute pericarditis include symptoms and signs. The symptoms of acute pericarditis are pain behind the sternum and in the precordial region, which often occurs during the fibrinous exudative phase of inflammation. The pain can radiate to the neck, left shoulder, left arm, and even the upper abdomen. The nature of the pain is sharp, related to respiratory movements. As the condition progresses, the pain can disappear and be replaced by difficulty breathing. Some patients may develop significant pericardial effusion leading to cardiac tamponade, resulting in symptoms such as difficulty breathing, edema, and other related symptoms. During acute pericarditis, the most diagnostically valuable sign is the pericardial friction rub, typically located in the precordial area. A typical friction rub can be heard consistent with atrial contraction, ventricular contraction, and ventricular relaxation, known as a triphasic friction rub, and so on.

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Is pericarditis serious?

Pericarditis refers to a group of diseases mainly characterized by inflammation and effusion of the pericardium. The severity of pericarditis depends on the condition of the disease. Firstly, if the inflammation and effusion of the pericardium are not severe, patients often experience symptoms such as chest tightness or chest pain. In general, this type of pericarditis is not considered severe. Secondly, if the inflammation and effusion of the pericardium are more pronounced, it can lead to pericardial effusion, especially in cases of large amounts of pericardial fluid. At this time, the condition is often quite serious, and it is essential to undergo formal treatment under the guidance of a doctor, including pericardial drainage therapy.

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Tuberculous pericarditis differential diagnosis

The differential diagnosis of tuberculous pericarditis requires differentiation from other types of pericardial inflammation, such as bacterial pericarditis and nonspecific infections that lead to cellular inflammation of the pericardium. In addition to infections that can cause pericarditis, other infectious diseases such as subacute endocarditis and infections caused by other microbes can also lead to pericarditis. Furthermore, some rheumatic autoimmune diseases can also present with pericarditis. It is necessary to perform pericardiocentesis and fluid examination to determine the specific cause.

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Cardiology
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Symptoms of acute pericarditis

Acute pericarditis is an acute inflammatory disease of the visceral and parietal layers of the pericardium, with the most common cause being viral infections. The hallmark of acute pericarditis is pain in the precardiac area behind the sternum. The nature of the pain is very sharp, typically occurring during the fibrinous exudation phase of inflammatory changes, caused by friction between the visceral and parietal layers of the pericardium. The pain can radiate to the neck, left shoulder, and even the upper abdomen. It is associated with respiratory movements and often worsens with coughing, deep breathing, or changing body positions. When fluid exudes into the pericardium, separating the visceral and parietal layers, the patient's pain may decrease or disappear. However, some patients may experience symptoms such as breathing difficulties and edema due to cardiac tamponade.

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Symptoms of Acute Pericarditis

Acute pericarditis is not a common disease in daily life. What symptoms or clinical manifestations will appear after someone develops acute pericarditis? The clinical manifestations are mainly reflected in the following aspects: First, patients often experience chest pain and shortness of breath, and this pain often has a certain relationship with breathing. Second, the electrocardiogram often shows changes with ST segment elevation. Third, during a physical examination, doctors can often hear pericardial friction rub, or may feel the sensation of pericardial friction. Based on these symptoms and signs, doctors often make a diagnosis of acute pericarditis.