Can you get tuberculosis on your own?

Written by Wang Xiang Yu
Pulmonology
Updated on September 07, 2024
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This question can be interpreted in two ways. First, whether every individual could potentially contract tuberculosis (TB) – to that, the answer is yes. Tuberculosis is a contagious disease, and we are all susceptible to the TB bacterium. Therefore, there is a chance, in our lifetimes, to be infected by the TB bacterium and consequently develop TB. The second interpretation revolves around whether a person could suddenly develop TB without specific reasons. Generally, this does not happen. In other words, a typical person would not contract TB unless they have been exposed to the TB bacterium. This means one does not contract TB arbitrarily; it occurs only after coming into contact with TB patients or the TB bacterium, leading to an infection in the lungs and resulting in TB.

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Written by Wang Xiang Yu
Pulmonology
1min 13sec home-news-image

What is tuberculosis?

Tuberculosis is a disease where the bacterium Mycobacterium tuberculosis infects the lungs. It is a persistent bacterium that grows slowly. Tuberculosis is an infectious disease and quite common historically, often referred to as consumption in the past, as mentioned in the novels of Lu Xun. In modern times, tuberculosis is relatively manageable if the infection has not developed resistance to drugs. Proper anti-tuberculosis treatment can result in a cure rate exceeding 90% on the first attempt. However, if the treatment is not adhered to correctly—if the patient stops taking the medication prematurely or does not follow the prescribed regimen—the bacteria may develop resistance, reducing the effectiveness of the treatment. This is particularly problematic in elderly patients, who might also experience adverse reactions to tuberculosis medications, making treatment difficult. Thus, while tuberculosis is generally treatable, infections with drug-resistant strains can be fatal if not managed properly.

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Written by Wang Xiang Yu
Pulmonology
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How is tuberculosis treated?

The primary treatment for tuberculosis is still chemotherapy, also simply called chemo, but the chemotherapy for tuberculosis is completely different from the anti-tumor chemotherapy we talk about in cancer, and the medications are also completely different. There are about more than ten anti-tuberculosis drugs, which can be divided into first-line and second-line drugs, and currently, there are third-line drugs under research. Chemotherapy for patients with pulmonary tuberculosis should be started early and administered in combination. The types of combined medication for patients with pulmonary tuberculosis generally involve three or more drugs. Some patients may exhibit drug resistance or intolerance to some drugs' side effects, and thus, second-line drugs may be used. Additionally, some patients, due to special conditions, may require four or five types of anti-tuberculosis drugs. It is crucial to strictly follow medical advice regarding how to medicate and treat. Furthermore, patients with pulmonary tuberculosis must ensure complete medication adherence, as the treatment duration for tuberculosis is quite long, typically requiring at least six months, and some patients may need one or even two years. Regular medication intake is very important because some patients might experience symptoms like coughing up blood or others, such as those with pleurisy, who might develop pleural effusion. Therefore, treatments targeted at other symptoms are necessary. Patients who cough up blood might need hemostatic drugs, while those with severe hemoptysis may even require interventional surgery. Some with tuberculous pleurisy might need to have pleural effusion drained. Additionally, some patients with pulmonary tuberculosis might experience adverse reactions to medications, such as liver or kidney failure, visual impairment, or numbness in the hands, which would require adjustments to their medication or changes based on their complications. Treatment should also be targeted toward these adverse reactions.

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Written by Han Jian Hua
Infectious Disease
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Can tuberculosis be cured?

Early diagnosis and standard treatment can often cure tuberculosis. Tuberculosis requires anti-tuberculosis treatment. Effective anti-tuberculosis treatment must follow five principles: early intervention, proper dosage, combination therapy, regular administration, and full-course treatment to ensure thorough treatment. Consistency is crucial; one must not stop taking medication, substitute drugs, or alter dosages on their own, as doing so not only makes it difficult to cure the disease but also increases the risk of developing drug resistance and complicates treatment further. Additionally, it is important to supplement nutrition appropriately and maintain a healthy diet in daily life. Since tuberculosis is a chronic, debilitating disease, it is advisable to consume foods rich in calories, proteins, and vitamins. Ensuring adequate rest and sleep is vital. Engaging in moderate physical activities, such as outdoor exercises, while avoiding strenuous activities and factors that could exacerbate conditions, such as overexertion, exposure to cold, and catching a cold, is also important.

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Written by Wang Xiang Yu
Pulmonology
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Is tuberculosis easily contagious?

Whether tuberculosis (TB) is easily transmitted primarily depends on the source of infection, which refers to the TB patients and the amount of Mycobacterium tuberculosis in their sputum. If TB bacilli can be detected in their sputum, and the quantity is substantial, then their infectiousness is indeed higher. However, if the TB patient has undergone treatment, or if there are only a few TB bacilli in their sputum, or none at all, then their infectiousness may not be as significant. The second factor is the mode of transmission, which mainly occurs through the respiratory tract. If TB patients can be isolated timely, or if they wear masks, and their sputum is properly managed, for example by wrapping the sputum in paper and burning it, then they are less likely to transmit the disease to others. TB generally involves susceptibility issues; even if someone has been vaccinated with BCG or the TB vaccine, they can still be reinfected. Therefore, controlling these three transmission pathways is essential to minimize the risk of contracting TB.

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Written by Li Jiao Yan
Neonatology
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Does the BCG vaccine prevent tuberculosis?

The BCG vaccine primarily prevents infection by the tuberculosis bacillus, so it can prevent pulmonary tuberculosis. The protective effect of the BCG vaccine is mainly achieved through inducing a cell-mediated immune response. After vaccination, a primary infection is formed, which is processed by macrophages that transmit the antigen information to immune-active cells, leading to the differentiation and proliferation of T cells and the formation of sensitized lymphocytes. When the body is re-infected with the tuberculosis bacillus, the macrophages and sensitized lymphocytes are activated, causing a specific immune response in the body, thereby resisting the infection by the tuberculosis bacillus. Therefore, the BCG vaccine mainly prevents pulmonary tuberculosis.