How is tuberculosis diagnosed?

Written by Xiong Hong Hai
Infectious Disease
Updated on March 18, 2025
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The diagnosis of tuberculosis primarily involves combining relevant clinical symptoms, such as whether there is cough, expectoration, low fever, night sweats, and blood in phlegm. It also requires considering the patient's chest imaging features, whether there is obvious infection, fresh exudation, cavities, as well as sputum tests. For example, if the sputum stain for acid-fast bacilli is positive, and the sputum culture is positive, using these comprehensive diagnostic methods, tuberculosis can be diagnosed, after which anti-tuberculosis treatment should be initiated.

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Does tuberculosis get inherited?

Is tuberculosis hereditary? Tuberculosis is not a hereditary disease; it is an infectious disease. Infectious diseases and hereditary diseases are two completely different concepts. Tuberculosis is generally infectious, which means that in a family, if parents are infected, they can easily transmit the tuberculosis bacteria to their children or others around them. Therefore, many people might mistakenly believe that tuberculosis is hereditary. However, this is not the case; tuberculosis is transmitted through the tuberculosis bacteria.

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How is tuberculosis treated?

The primary treatment for tuberculosis is still chemotherapy, also simply called chemo, but the chemotherapy for tuberculosis is completely different from the anti-tumor chemotherapy we talk about in cancer, and the medications are also completely different. There are about more than ten anti-tuberculosis drugs, which can be divided into first-line and second-line drugs, and currently, there are third-line drugs under research. Chemotherapy for patients with pulmonary tuberculosis should be started early and administered in combination. The types of combined medication for patients with pulmonary tuberculosis generally involve three or more drugs. Some patients may exhibit drug resistance or intolerance to some drugs' side effects, and thus, second-line drugs may be used. Additionally, some patients, due to special conditions, may require four or five types of anti-tuberculosis drugs. It is crucial to strictly follow medical advice regarding how to medicate and treat. Furthermore, patients with pulmonary tuberculosis must ensure complete medication adherence, as the treatment duration for tuberculosis is quite long, typically requiring at least six months, and some patients may need one or even two years. Regular medication intake is very important because some patients might experience symptoms like coughing up blood or others, such as those with pleurisy, who might develop pleural effusion. Therefore, treatments targeted at other symptoms are necessary. Patients who cough up blood might need hemostatic drugs, while those with severe hemoptysis may even require interventional surgery. Some with tuberculous pleurisy might need to have pleural effusion drained. Additionally, some patients with pulmonary tuberculosis might experience adverse reactions to medications, such as liver or kidney failure, visual impairment, or numbness in the hands, which would require adjustments to their medication or changes based on their complications. Treatment should also be targeted toward these adverse reactions.

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Written by Xiong Hong Hai
Infectious Disease
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Is tuberculosis serious?

Tuberculosis is a relatively serious disease, but if it is treated and managed promptly in the early stages, it often can be brought under control and most cases can completely recover. If the disease is allowed to progress unchecked, it can develop from ordinary tuberculosis into an especially severe form of the disease, even endangering life and leading to extrapulmonary tuberculosis. The severity of tuberculosis depends largely on the extent of damage to the lungs and whether there is extrapulmonary tuberculosis. Once tuberculosis is confirmed, scientifically sound and appropriate anti-tuberculosis treatment should be undertaken.

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Written by Xiong Hong Hai
Infectious Disease
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Is tuberculosis contagious?

Actually, not all cases of tuberculosis are contagious; only those in which tuberculosis bacteria can be found in the sputum are infectious. Many cases are non-infectious. Among all cases of active tuberculosis, only about 30% have detectable tuberculosis bacteria in their sputum. The remaining 70% do not have detectable tuberculosis bacteria and thus are not contagious. Whether tuberculosis is contagious or not, once the diagnosis of tuberculosis is confirmed, scientific and rational comprehensive anti-tuberculosis treatment is required.

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Written by Xiong Hong Hai
Infectious Disease
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Does tuberculosis cause coughing at night?

Patients with tuberculosis often experience coughing at night, as well as in the early morning. Coughing and expectorating phlegm are common symptoms of tuberculosis. They are often accompanied by low-grade fever, night sweats, afternoon fever flush, weight loss, and blood in the sputum. In severe cases, symptoms can include chest tightness and difficulty breathing. Tuberculosis can be completely cured. Once it is confirmed as a tuberculosis infection, it is necessary to undergo scientific and reasonable anti-tuberculosis treatment, taking into account the actual circumstances.