How do you get pyelonephritis?

Written by Li Liu Sheng
Nephrology
Updated on January 01, 2025
00:00
00:00

Pyelonephritis is a clinical type of urinary tract infection, which refers to the inflammatory disease caused by the growth and reproduction of various pathogens in the renal pelvis. Pyelonephritis is usually divided into acute pyelonephritis and chronic pyelonephritis. Acute pyelonephritis is primarily characterized by frequent urination, urgency, painful urination, chills, fever, back pain, overall muscle soreness, and tenderness or percussion pain in one or both kidney areas. Chronic pyelonephritis, on the other hand, shows varying degrees of bilateral renal damage, reduced kidney size, rough surfaces, renal papillary scars, renal tubular atrophy, and chronic inflammation signs such as lymphocyte infiltration in the renal interstitium. Chronic pyelonephritis typically presents with low-grade fever, weight loss, backache, and anemia. Therefore, sufficient attention should be given to pyelonephritis, as chronic pyelonephritis can lead to uremia in patients.

Other Voices

doctor image
home-news-image
Written by Zhou Qi
Nephrology
49sec home-news-image

Pyelonephritis is an infection of the kidneys

In fact, pyelonephritis is not really nephritis; it is actually a type of bacterial inflammatory infection. Bacteria can infect many parts of the body. If the urinary system is infected and it reaches the renal pelvis and calyces, it is referred to as pyelonephritis. Over 95% of pyelonephritis cases are caused by bacterial infections, and 70% are due to Escherichia coli. Generally, this bacteria enters the urinary system from the urethral opening and ascends to the renal pelvis and calyces, where it proliferates and causes an inflammatory response. The main clinical symptoms of the patient are fever and back pain, and the patient may also experience gross hematuria (visible blood in urine).

doctor image
home-news-image
Written by Zhou Qi
Nephrology
1min 7sec home-news-image

Can pyelonephritis be cured?

Whether pyelonephritis can be cured mainly depends on whether the patient has predisposing factors for urinary tract infections. These factors primarily include: Firstly, abnormalities in the anatomical structure of the urinary tract that may lead to obstruction of urine excretion, such as urological system stones, tumors, prolonged indwelling catheters, congenital abnormalities of the urinary system, and others. Additionally, there are some conditions that may lead to a decreased immune response, such as elderly individuals who are bedridden, those with diabetes, or patients using immunosuppressants. If the aforementioned factors are present, treatment of such cases of pyelonephritis might be challenging, with patients possibly experiencing recurrent episodes and potentially progressing to chronic pyelonephritis, eventually becoming difficult to cure completely. However, if none of these factors exist, the majority of cases with simple acute pyelonephritis can be cured and controlled by medication.

doctor image
home-news-image
Written by Li Liu Sheng
Nephrology
1min 4sec home-news-image

How do you get pyelonephritis?

Pyelonephritis is a clinical type of urinary tract infection, which refers to the inflammatory disease caused by the growth and reproduction of various pathogens in the renal pelvis. Pyelonephritis is usually divided into acute pyelonephritis and chronic pyelonephritis. Acute pyelonephritis is primarily characterized by frequent urination, urgency, painful urination, chills, fever, back pain, overall muscle soreness, and tenderness or percussion pain in one or both kidney areas. Chronic pyelonephritis, on the other hand, shows varying degrees of bilateral renal damage, reduced kidney size, rough surfaces, renal papillary scars, renal tubular atrophy, and chronic inflammation signs such as lymphocyte infiltration in the renal interstitium. Chronic pyelonephritis typically presents with low-grade fever, weight loss, backache, and anemia. Therefore, sufficient attention should be given to pyelonephritis, as chronic pyelonephritis can lead to uremia in patients.

doctor image
home-news-image
Written by Zhou Qi
Nephrology
58sec home-news-image

Principles of treatment for pyelonephritis

Pyelonephritis, also known as an upper urinary tract infection, is a bacterial inflammation, with over 95% being caused by bacterial infections, among which 70% are caused by Escherichia coli. Therefore, as a bacterial infection-induced inflammation, antibiotic treatment is of course necessary. Clinically, third-generation cephalosporins or fluoroquinolone antibiotics are often chosen for bactericidal treatment. For acute pyelonephritis, it is generally recommended that medication be administered for 14 days, alongside measures such as increased water intake and frequent urination. In cases of chronic pyelonephritis, a low-dose, long-course antibacterial treatment, such as using nitrofurantoin, may also be employed, with continuous medication for two months. (Please consult a clinical doctor for specific medication use; do not self-medicate.)

doctor image
home-news-image
Written by Zhou Qi
Nephrology
45sec home-news-image

What causes acute pyelonephritis?

Acute pyelonephritis, also known as an upper urinary tract infection, occurs when certain pathogens enter the urinary system and cause inflammation in areas such as the renal pelvis and calyces. Patients typically exhibit symptoms such as fever, back pain, and may also experience visible blood in the urine. The condition often has a severe onset. The common pathogens causing this type of infection primarily include bacteria, fungi, and viruses, among which the vast majority of cases are caused by bacterial infections. Furthermore, Gram-negative bacilli constitute the majority of these bacteria, with Escherichia coli being the most common.