The most severe complication of mitral valve insufficiency is the occurrence of left-sided heart failure, or left and right heart failure, eventually leading to total heart failure.

Since the mitral valve is a type of rheumatic heart disease and also a cardiac valve disorder, cardiac function is abnormal at this time. If this condition is not treated promptly, it will further lead to a decline in cardiac function, causing the occurrence of heart rate failure.

Patients mainly exhibit symptoms of ischemia and hypoxia, as well as edema in both lower limbs and some situations of water and sodium retention. It is necessary to actively use cardiotonic diuretics to improve the patient's cardiac function.