Tetanus

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Written by Liu Huan Huan
General Surgery
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How to rescue from tetanus allergy

In clinical settings, when administering tetanus injections, it is very easy for allergic reactions to occur, even severe complications like anaphylactic shock. In such cases, the following emergency measures can be taken: First, establish an intravenous access immediately, then start the patient on infusion therapy; Second, if the patient experiences a drop in blood pressure, vasopressor agents can be used for pressor therapy; Third, it's essential to provide the patient with cardiac monitoring, oxygenation, and other supportive treatments. In addition, it's crucial to use anti-allergy medications. There are many anti-allergic drugs available clinically, and the specific medication to be used should be decided based on the patient's specific condition. (Please administer medications under the guidance of a professional physician, and do not self-medicate.)

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Written by Xu Jun Hui
General Surgery
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When to get a tetanus shot?

Tetanus is caused by the invasion of the body by tetanus bacillus, a type of anaerobic bacterium that generally thrives in anoxic environments or heavily contaminated wounds such as those exposed to polluted soil or rust. Therefore, if the wound is deep, is in an anoxic environment, or is severely contaminated with soil, rust, or is an open fracture with expanded area, explosive injury, gunshot wound, or animal bite, tetanus treatment is required. Tetanus injections include tetanus toxoid, which requires a skin test, and tetanus immunoglobulin, which does not require a skin test, with an injection generally recommended within 24 hours.

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Written by Zhang Peng
General Surgery
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How is tetanus diagnosed?

For the diagnosis of tetanus, it mainly relies on relevant medical history and clinical manifestations. In terms of laboratory diagnosis, most cases involve culture of Clostridium tetani from wound tissue or polymerase chain reaction testing. Generally, a positive result can confirm a diagnosis of tetanus, but a negative result does not rule it out. Most laboratories are unable to perform these tests, and even if tetanus antibodies reach a protective level, it does not exclude a diagnosis of tetanus. If the patient has a clear history of injury or animal bites, and presents with symptoms such as lockjaw, a sardonic smile, muscle rigidity, difficulty swallowing, or persistent spasms, tetanus should be considered promptly and relevant treatment initiated.

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Written by Ai Bing Quan
General Surgery
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What department should I go to for tetanus?

Tetanus is a special type of infection that should be treated through routine surgery or emergency surgery. It is caused by the tetanus bacillus, an anaerobic bacterium typically found in feces. Tetanus is easily contracted after an injury, especially in deep wounds. Clinically, tetanus manifests initially with difficulty in opening the mouth, followed by a grimacing smile, convulsions, and respiratory difficulties later on. Preventive measures include going to the hospital immediately after an injury to have the wound cleaned at the department of general surgery or emergency surgery and concurrently receiving a tetanus serum injection.

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Written by Li Jin Quan
General Surgery
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Can you drink alcohol with tetanus?

Tetanus is usually caused by the toxins produced by Clostridium tetani entering the bloodstream, leading to specific clinical manifestations, including muscle tension and rigidity. In severe cases, it can cause respiratory confusion and respiratory failure. If tetanus patients consume alcohol, because alcohol can increase blood circulation and dilate blood vessels, it facilitates the absorption of toxins, accelerating and worsening the symptoms of tetanus. Therefore, patients with tetanus should not drink alcohol and should maintain a light diet.

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Written by Xu Jun Hui
General Surgery
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Which part of the body is the tetanus shot administered?

Tetanus injections are given as intramuscular injections in the upper arm or the buttock. Tetanus vaccines include tetanus antitoxin, which requires a skin test. Patients with a positive skin test must either undergo desensitization therapy or avoid using it, and can switch to tetanus immunoglobulin, which doesn't require a skin test but is more expensive than tetanus antitoxin. The purpose of the tetanus shot is to prevent infection by Clostridium tetani, an anaerobic bacterium. It is particularly important for patients with deep wounds or heavily contaminated wounds; or wounds contaminated with rust or soil to receive tetanus treatment to prevent Clostridium tetani from colonizing the body through wound mucosa and producing neurotoxins that affect breathing.

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Written by Zhang Peng
General Surgery
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How long does tetanus antibody last?

The duration of tetanus antibodies varies under two scenarios. The first is passive immunity, which is achieved through injections such as tetanus antitoxin or tetanus immunoglobulin. The duration of immunity provided by these injections is relatively short. Typically, tetanus antitoxin lasts about four days, while tetanus immunoglobulin can last up to three weeks. After this period, the levels of antibodies gradually decrease, and the body may no longer be protected. Therefore, a single application of tetanus antitoxin or immunoglobulin does not provide long-lasting immunity. The second scenario involves antibodies produced by active immunity, generally through the injection of a vaccine made from attenuated tetanus bacilli. Antibodies usually start to develop about ten days after vaccination, with levels gradually increasing over two to three months and remaining high. This type of immunity lasts up to about ten years, but it is not lifelong. Regular boosters, guided by relevant tests, are required to maintain immunity.

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Written by He Zong Quan
General Surgery
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Can a festering wound lead to tetanus?

Wound suppuration and contracting tetanus are two different concepts. Wound suppuration primarily occurs when there is an infection at the wound site, which spreads due to lack of significant control over the infection focus. We need to actively locate the infection source, perform thorough surgical debridement and drainage, use sensitive antibiotics as needed globally, and change dressings in a timely manner to manage the infection. Tetanus, on the other hand, is typically considered when the wound is too deep and visibly contaminated, often by rusty, sharp objects causing the infection. In such cases, thorough surgical cleansing of the wound is essential to prevent surface contamination, along with the systemic use of tetanus antitoxin to reduce or prevent a tetanus infection.

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Written by Zhang Peng
General Surgery
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How long can a tetanus shot last?

The duration of a tetanus shot can be considered from two different immunization processes. In the case of passive immunity, it typically lasts for a shorter duration. If tetanus antitoxin is administered, it generally lasts between two to four days, while tetanus immunoglobulin can last up to three weeks. After this period, the level of antibodies gradually decreases, and the body may no longer be protected. Therefore, a single use of tetanus antitoxin or immunoglobulin does not provide lasting immunity. The second method is what we commonly refer to as getting a tetanus vaccine, which is a process of active immunity. Usually, for active immunity, the tetanus bacterium is processed and made into a weakened vaccine for injection. Antibodies can be produced after about ten days, and within two to three months, the level of antibodies in the body gradually increases and remains at a high titer, providing immunity for up to about ten years.

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Written by Li Jin Quan
General Surgery
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Can tetanus be fatal?

Firstly, it must be acknowledged that if a patient with tetanus does not receive timely treatment, it can be fatal. When tetanus infection occurs, the early symptoms mainly include dizziness, headache, fatigue, loss of appetite, weak chewing, sore jaw muscles, or some heightened reflexes, or muscle tension. As tetanus worsens, it can manifest as typical clinical symptoms, mainly lockjaw, difficulty opening the mouth, sardonic smile, stiff neck, opisthotonos, and in severe cases, difficulty breathing, respiratory arrest, and even cardiac arrest. If emergency treatment is not administered promptly, the patient can die.