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lymphoma
What are the early symptoms of lymphoma?
Lymphoma is a malignant tumor of the hematological system, with early symptoms including painless enlargement of the lymph nodes in the neck, which are generally well-movable and firm or hard in texture early on, without inflammatory changes such as redness, swelling, heat, or pain. Additionally, lymphomas occurring in the gastrointestinal tract can clinically present with symptoms such as upper abdominal fullness and discomfort, bloating, nausea, recurrent acid reflux, and belching. Lymphomas occurring in the respiratory system can manifest clinically with symptoms such as cough, shortness of breath after activity, and chest pain. Lymphomas occurring in the brain can cause dizziness, headaches, movement disorders, ataxia, and abnormal gait.
What is lymphoma Ki-67?
Lymphoma Ki67, also known as the proliferation index, is one of the indicators in immunohistochemistry performed after the pathological diagnosis of lymphoma. If this proliferation index is higher, it indicates that the activity of the tumor is stronger, and its proliferation is more active, thus the tumor should be given sufficient attention. Of course, active treatment should be pursued. Therefore, Ki67 reflects the activity of a tumor; if the index is very high, greater than 90%, it sometimes implies that the tumor can grow very rapidly, or not only grows significantly but might also spread to many places.
What are the symptoms of lymphoma spread?
The symptoms of lymphoma spread depend primarily on its original location. Generally, the most common site of origin is in the neck. Spread means that it has moved to other areas, so it may have spread to the armpits, groin, or popliteal fossa. If there is swelling or a tumor in the lymph nodes in these areas, it manifests as a tumor that can be felt in those specific locations, like in the groin or armpits. Of course, it is possible that it may spread to substantive organs, such as the lungs. If it spreads to the lungs, symptoms might include shortness of breath, coughing, and blood in the sputum.
How is Hodgkin's lymphoma treated?
The treatment of Hodgkin's lymphoma is based on various factors including the stage of the disease as well as the general condition of the patient, among other comprehensive considerations. For patients with early stage Hodgkin's lymphoma, commonly referred to as localized Hodgkin's lymphoma, the treatment principle is a combination of chemotherapy and radiotherapy. A rational comprehensive treatment can achieve a five-year survival rate of 80% to 90%. For advanced-stage patients, such as those with stage IV Hodgkin's lymphoma, the treatment primarily consists of systemic chemotherapy. Therefore, the choice of a specific treatment plan must also consider a variety of factors based on the patient's overall condition.
Lymphoma rash symptoms
The rash associated with lymphoma is not much different from common rashes; they are both characterized by red papules. However, lymphoma is not an isolated disease. For instance, in patients, one can feel lumps on the neck or upper clavicle area, but they may also exhibit systemic symptoms such as fever, night sweats, weight loss, fatigue, lack of appetite, anemia, chest pain, and other symptoms because it is a systemic disease. Thus, it may cause these systemic symptoms. The rash can also cause itching of the skin.
Causes of Malignant Lymphoma
The causes of malignant lymphoma are the result of multiple factors. First, it is associated with infections by bacteria or viruses, such as the well-documented chronic infection with Helicobacter pylori, which is closely related to the occurrence of lymphoma associated with the gastric mucosa. Second, immunodeficiency conditions, like in AIDS patients or those who have been taking immunosuppressive drugs for a long period, have a higher likelihood of developing malignant lymphoma compared to the general population. Third, chemical or physical factors, such as environmental carcinogens and electromagnetic radiation, can also lead to malignant lymphoma. Other factors, such as long-term use of certain drugs like phenytoin or pseudoephedrine, and a genetic predisposition, can also be causes of malignant lymphoma.
Lymphoma has what manifestations?
The symptoms of lymphoma, simply put, are that some people feel a lump on their neck or in their armpit; it starts as a sudden appearance of a swelling that gets larger over time, sometimes not just one, but multiple lumps clustered together. This is indeed the most common symptom, where one can feel something on their neck, including under the jaw or the chin, noticing suddenly a nodule has formed, whether it's the size of a chicken egg or otherwise. That's one aspect. The second involves systemic symptoms, which primarily include fever, night sweats, and weight loss. These three symptoms are quite common.
early symptoms of Hodgkin's lymphoma
Malignant lymphoma refers to a type of malignant tumor that originates in the lymph nodes or extranodal organs or tissues. Therefore, Hodgkin's lymphoma is a type of lymphoma. Its early symptoms mainly start with the enlargement of superficial lymph nodes throughout the body, with 90% of Hodgkin's lymphoma patients presenting with enlargement of superficial lymph nodes as an early symptom when they seek medical advice. The most common superficial lymph nodes are those above the collarbone and in the neck, but enlargement can also occur in the axillary and inguinal lymph nodes, which are also some of the more common early clinical manifestations seen in practice.
Early symptoms of lymphoma
The early symptoms of lymphoma involve the painless enlargement of both superficial and deep lymph nodes, most commonly located in areas such as the neck, armpits, and groin. Of course, lymphoma also presents with systemic symptoms, such as fever, night sweats, weight loss, and skin itching. Since lymphoma commonly occurs in the neck, armpits, and groin, if it develops in other areas, such as the lungs or elsewhere, it may cause respiratory symptoms, including coughing, expectoration, and shortness of breath.
Are all lymphomas malignant?
Tumors can be benign or malignant; malignant tumors are commonly referred to as cancer. Lymphoma, because it originates from lymph nodes or tissues or organs outside the lymph nodes, is a type of malignant tumor, and thus it is called lymphoma. All lymphomas are malignant; there are no benign lymphomas. However, based on specific pathological types, lymphomas are classified into two main categories: non-Hodgkin lymphoma and Hodgkin lymphoma, but all lymphomas are malignant.