lymphoma

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Written by Liu Liang
Oncology
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Lymphoma registration: which department?

Patients diagnosed with lymphoma can register under the departments of Hematology or Oncology, as both departments can administer chemotherapy. However, radiation therapy can only be conducted in the Oncology department. Each hospital may have slightly different categorizations for departments and diseases. However, for a patient initially presenting with lymphoma, who has not yet been diagnosed and primarily shows symptoms of painless lymph node enlargement, they can register under General Surgery. After completing necessary examinations like an ultrasound, if lymphoma is suspected, a lymph node excision biopsy is usually performed in General Surgery.

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Written by Peng Li Bo
Oncology
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Is lymphoma contagious?

Lymphoma is not contagious, as it is not an infectious disease but a tumoral disease. Therefore, it is not contagious, and when seeking medical treatment for lymphoma, patients do not go to the department of infectious diseases. Typically, treatment is conducted in the oncology department or in the hematology department specializing in lymphoma. Thus, lymphoma is not contagious because it is not caused by an infectious pathogen. It is a solid tumor that is tangible and visible.

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Written by Peng Li Bo
Oncology
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What are the symptoms of lymphoma?

The symptoms of lymphoma usually involve painless, progressive enlargement of the lymph nodes, typically located in areas like the neck, under the jaw, and below the chin. However, beyond these localized symptoms, lymphoma can also present with systemic symptoms, which include fever, night sweats, weight loss, as well as rashes and itching skin. Thus, lymphoma encompasses both local and systemic symptoms.

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Written by Liu Liang
Oncology
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Lymphoma PR means "partial remission" of lymphoma.

"Lymphoma PR refers to an assessment of the effectiveness of chemotherapy. Typically, in clinical practice, after two rounds of chemotherapy, a comprehensive examination is conducted to assess the effectiveness of the treatment. PR stands for partial remission, which means that the measurable size of the tumor has reduced by at least 30% and has remained stable for four weeks. Clinically, this is referred to as PR, or partial remission, and it is an assessment of the effectiveness of chemotherapy."

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Written by Liu Liang
Oncology
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The difference between lymphoma and lymphatic cancer

Cancer, commonly referred to as malignant tumors in everyday language, is generally known to the public simply as cancer—for example, lung cancer, liver cancer, colon cancer, etc. It specifically refers to malignant tumors that occur in epithelial tissue, which we call cancer. Lymphoma, on the other hand, refers to malignant tumors that occur in lymph nodes, or in extranodal organs or tissues, which we call lymphoma. There are also malignant tumors that occur in mesenchymal tissue, known as sarcomas. In fact, lymphoma is also a type of malignant tumor, so people commonly refer to it as lymphatic cancer. Therefore, lymphoma and lymphatic cancer are essentially the same disease, with lymphatic cancer specifically referring to lymphoma.

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Written by Zhang Xiao Le
Hematology
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How to rule out lymphoma in children

Lymphoma is a malignant tumor originating from the lymphatic system. The main clinical manifestation is painless lymph node enlargement, which can occur in superficial lymph nodes such as in the neck, armpits, or groin, as well as deeper lymph nodes in the mediastinum or abdominal cavity. In pediatric patients with lymphoma, a significant number also present with abdominal pain, intestinal obstruction, or intussusception, which often indicates intestinal lymphoma. If children exhibit lymph node enlargement or deep lymph node enlargement is discovered through imaging studies, it is necessary to perform a puncture or biopsy and conduct a pathological examination to further confirm whether it is lymphoma.

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Written by Peng Li Bo
Oncology
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Hodgkin's lymphoma symptoms and signs

Actually, whether it is Hodgkin's lymphoma or non-Hodgkin's lymphoma, the symptoms and signs are quite similar. In terms of symptoms, because lymphoma mainly occurs as a lesion in the lymph nodes, it is characterized by superficial, localized enlargement of the lymph nodes. Common locations include the neck, then the armpits, and the groin—areas where lymph nodes are more prevalent. It manifests as a local swelling; simply put, you might feel a lump or a tumor on your neck, which is the most common symptom. Additionally, there are other systemic symptoms including fever, weight loss, night sweats, and itchy skin, among others. As for the physical signs, it mainly refers to palpable superficial lymph node enlargement upon examination.

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Written by Zhou Chen
Oncology
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What to check for malignant lymphoma?

The examination of lymphoma first requires routine blood tests and blood smears. When aggressive lymphoma invades the bone marrow, anemia, decreased white blood cells, and platelets may occur, and lymphoma cells can appear in peripheral blood; therefore, bone marrow smears and biopsies are necessary. Additionally, blood biochemistry is important, as an increase in lactate dehydrogenase is associated with tumor burden and is an indicator of poor prognosis. Furthermore, Hodgkin's lymphoma may involve the central nervous system, so patients with symptoms of central nervous system involvement need to undergo cerebrospinal fluid examination. The most important aspect of lymphoma is the histopathological examination. Based on the histopathological examination, the pathological staging is determined, and genetic rearrangement can also be performed.

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Written by Peng Li Bo
Oncology
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Is lymphoma hereditary?

Lymphoma is generally not hereditary, as it is not a genetic disease. However, I must mention that most neoplastic diseases do have some hereditary factors to some extent. The reason for this is that the cause of lymphoma is currently unclear, and it may be related to genetic mutations, which raises the issue of heredity. Another point is that heredity often refers to transmission among direct relatives. This means there could be a problem in that you might share similar environments and lifestyles, including diet. If there are factors in your diet or living environment that could trigger lymphoma, and you are both exposed to these factors, then your probability of developing lymphoma could indeed be higher than in patients without a family history, leading to such a concern.

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Written by Peng Li Bo
Oncology
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How is malignant lymphoma treated?

The common treatments for malignant lymphoma currently include chemotherapy, targeted therapy, radiation therapy, and the use of immunosuppressants. There are also newer treatments such as cell reinfusion. The choice of treatment for malignant lymphoma definitely depends on the specific pathological type. Another factor is the stage of the lymphoma—it could be in stages one, two, three, or four, which definitely matters. The third factor is whether the lymphoma causes any symptoms or signs in the patient because some minor lymphomas may allow for observation and waiting, but many require active treatment.