Hodgkin's lymphoma symptoms and signs

Written by Peng Li Bo
Oncology
Updated on January 31, 2025
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Actually, whether it is Hodgkin's lymphoma or non-Hodgkin's lymphoma, the symptoms and signs are quite similar. In terms of symptoms, because lymphoma mainly occurs as a lesion in the lymph nodes, it is characterized by superficial, localized enlargement of the lymph nodes. Common locations include the neck, then the armpits, and the groin—areas where lymph nodes are more prevalent. It manifests as a local swelling; simply put, you might feel a lump or a tumor on your neck, which is the most common symptom. Additionally, there are other systemic symptoms including fever, weight loss, night sweats, and itchy skin, among others. As for the physical signs, it mainly refers to palpable superficial lymph node enlargement upon examination.

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Written by Liu Liang
Oncology
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Early symptoms of lymphoma

The early symptoms of lymphoma patients are primarily due to its predilection for lymph nodes, with the majority of cases initially presenting with swollen lymph nodes in the neck or collarbone area. These lymph nodes usually enlarge progressively without pain, which is the most common early clinical symptom. However, some specific types of lymphoma, such as nasal NKT lymphoma, present with localized symptoms like nasal congestion, nosebleeds, or a runny nose. There are also lymphomas originating in the stomach, part of the digestive tract, whose symptoms include upper abdominal pain, nausea, or vomiting. Furthermore, some lymphomas originate in the skin, manifesting as skin nodules. Therefore, depending on the site of occurrence, the symptoms can vary, but the enlargement of superficial lymph nodes remains the primary clinical manifestation in most cases.

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Written by Peng Li Bo
Oncology
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How is malignant lymphoma treated?

The common treatments for malignant lymphoma currently include chemotherapy, targeted therapy, radiation therapy, and the use of immunosuppressants. There are also newer treatments such as cell reinfusion. The choice of treatment for malignant lymphoma definitely depends on the specific pathological type. Another factor is the stage of the lymphoma—it could be in stages one, two, three, or four, which definitely matters. The third factor is whether the lymphoma causes any symptoms or signs in the patient because some minor lymphomas may allow for observation and waiting, but many require active treatment.

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Oncology
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Is lymphoma a type of cancer?

Cancer refers to malignant tumors. Tumors are classified into benign and malignant types, with the malignant ones commonly referred to as cancer. Often discussed are those originating from epithelial cells, termed carcinomas, such as lung cancer and breast cancer. However, there are special types such as those originating from mesenchymal tissue, called sarcomas, including synovial sarcoma and osteosarcoma, which are also malignant tumors and belong to cancer. Lymphoma, a malignant tumor originating from lymph nodes or extranodal tissues or organs, is also classified as cancer.

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Written by Liu Liang
Oncology
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early symptoms of Hodgkin's lymphoma

Malignant lymphoma refers to a type of malignant tumor that originates in the lymph nodes or extranodal organs or tissues. Therefore, Hodgkin's lymphoma is a type of lymphoma. Its early symptoms mainly start with the enlargement of superficial lymph nodes throughout the body, with 90% of Hodgkin's lymphoma patients presenting with enlargement of superficial lymph nodes as an early symptom when they seek medical advice. The most common superficial lymph nodes are those above the collarbone and in the neck, but enlargement can also occur in the axillary and inguinal lymph nodes, which are also some of the more common early clinical manifestations seen in practice.

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Written by Liu Liang
Oncology
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Lymphoma PR means "partial remission" of lymphoma.

"Lymphoma PR refers to an assessment of the effectiveness of chemotherapy. Typically, in clinical practice, after two rounds of chemotherapy, a comprehensive examination is conducted to assess the effectiveness of the treatment. PR stands for partial remission, which means that the measurable size of the tumor has reduced by at least 30% and has remained stable for four weeks. Clinically, this is referred to as PR, or partial remission, and it is an assessment of the effectiveness of chemotherapy."