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Liver cancer
What should I do if I have liver cancer and a fever of 38 degrees Celsius?
Liver cancer patients experiencing a fever of 38°C can be seen in the following scenarios: The first type is tumor-related fever. In liver cancer patients, especially those in the advanced stages or with large tumors, a fever of around 38°C can occur in the absence of infection symptoms. This tumor fever is related to various mediators released into the blood by the tumor. The second type is infectious fever. Cancer patients undergoing anti-tumor treatment may experience immunosuppression and concurrent infections. This type of fever often exceeds 38.5°C but can also occur around 38°C in the early stages, often accompanied by symptoms of infection such as coughing, sputum production, abdominal pain, and diarrhea. The third type is treatment-related fever. Patients with liver cancer may experience a fever of around 38°C on the day of and several days following interventional treatments.
Is primary liver cancer hereditary?
Primary liver cancer is usually not hereditary, but the reason why it tends to appear in families in China is mainly due to the widespread infection of hepatitis B virus, which then leads to a significant correlation with hepatic cirrhosis caused by hepatitis B. It is well known that the hepatitis B virus is contagious and can easily be transmitted within families and from mother to child. Therefore, it is not uncommon to see several cases of liver cancer within the same family, indicating a familial aggregation. Another factor is related to dietary habits, for example, the infection of aflatoxin, which is mainly found in moldy peanuts. If the dietary habits within a family are similar, then, of course, the likelihood of occurrence is certainly higher.
Will people with early-stage liver cancer experience weight loss?
Patients with early-stage liver cancer generally do not experience weight loss; weight loss is more commonly a clinical manifestation in patients with late-stage liver cancer. The reason for weight loss in liver cancer patients is due to the damage caused by cancerous tissue to liver function, leading to reduced synthesis of albumin. Furthermore, patients with liver cancer often experience a significant decrease in food intake, resulting in insufficient intake of nutrients such as albumin. Additionally, the progression of liver cancer tumors requires the consumption of a large amount of the body's albumin. Therefore, due to these factors, many patients with late-stage liver cancer exhibit clinical manifestations of weight loss. Moreover, besides not experiencing weight loss, patients with early-stage liver cancer also do not typically present with typical clinical symptoms. Many patients are asymptomatic, and as the lesion progresses, the cancer spreads, possibly leading to clinical manifestations associated with tumor spread. For example, pain in the liver area, a significant decrease in food intake, fatigue, fever, pain, and some patients may also exhibit symptoms of metastasis such as headaches, vomiting, abdominal pain, and abdominal distension.
Can alpha-fetoprotein confirm liver cancer?
Alpha-fetoprotein is a type of oncofetal antigen and a glycoprotein. It is used clinically as a highly specific marker for diagnosing primary liver cancer. However, elevated alpha-fetoprotein levels do not definitively indicate liver cancer, as although it is a tumor marker with diagnostic significance, elevated levels can also be seen in patients with liver cirrhosis or chronic hepatitis. Additionally, increased alpha-fetoprotein can occur in pregnant women or in the presence of other types of cancer, so further investigation is necessary to confirm the cause.
Can gallbladder stones turn into liver cancer?
Long-term pathological changes from hepatobiliary calculi can lead to liver cancer. Hepatobiliary calculi generally refer to intrahepatic bile duct stones. When these stones grow in a single duct and gradually increase in number and size, they can cause obstruction of the bile duct. Obstruction of the bile duct subsequently leads to cholangitis, which involves repeated inflammatory irritation. This, in turn, can cause malignant transformation of the bile duct cells. Following this transformation, a tumor forms, which can develop into cholangiocellular carcinoma, a type of liver cancer. Therefore, if intrahepatic bile duct stones cause long-term inflammatory stimulation, it can lead to cancerous changes and result in liver cancer. Thus, if intrahepatic bile duct stones have already caused noticeable clinical symptoms such as abdominal pain, fever, and liver function abnormalities, aggressive surgical treatment should be considered.
How to rule out liver cancer when experiencing right shoulder pain?
Some liver cancer patients may experience abdominal pain that radiates to the shoulder and back, resulting in right shoulder pain. Therefore, when a patient presents with right shoulder pain, to rule out the possibility of liver cancer, some laboratory tests or radiological examinations can be conducted, and if necessary, histopathological examinations can also be performed. If hematological examination does not show an abnormal increase in AFP levels, and radiological examinations do not reveal any abnormal liver conditions such as large masses, nodular tumors, or diffuse liver lesions, and there is no history of hepatitis or cirrhosis, it is generally possible to rule out right shoulder pain caused by liver cancer. To determine the exact cause of the pain, examinations such as X-rays of the right shoulder, CT scans, and if necessary, MRI or bone scans can be conducted to exclude right shoulder pain caused by liver cancer lesions.
The difference between primary liver cancer and metastatic liver cancer
Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to cancers that start in other parts of the body and then spread to the liver through lymphatic and blood circulation, among other routes. Another difference is that primary liver cancer is more likely to be a single lesion, while metastatic liver cancer generally involves multiple lesions. Regarding the differences between primary and metastatic liver cancer, their treatment methods also differ. For primary liver cancer, interventional chemotherapy or surgery, such as hepatic lobectomy, can be performed if the tumor is small. In contrast, metastatic liver cancer usually involves multiple lesions, making surgery alone challenging. Additionally, the primary tumor also requires treatment.
Which is more treatable, primary liver cancer or metastatic liver cancer?
Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to malignant tumors from other parts of the body that have spread to the liver. As to which is easier to treat, it is generally difficult to determine and depends on the control of the primary lesion in cases of metastatic liver cancer; both might be challenging to treat. However, if the lesion in primary liver cancer is relatively small, there may still be an opportunity for surgical treatment. In general, metastatic liver cancer is not amenable to curative surgery because the primary lesion also requires treatment. But in terms of the rate of progression or severity, metastatic liver cancer might progress more slowly, while primary liver cancer generally progresses quite rapidly, making it also very difficult to treat.
Can hepatitis B turn into liver cancer?
If hepatitis B is not effectively controlled, it can further develop into liver cancer. However, if patients adhere to standard treatment, regular check-ups, rest adequately, eat healthily, and abstain from alcohol, most conditions can be effectively controlled, significantly reducing the likelihood of developing liver cancer. Therefore, patients need not worry too much; maintaining a positive and optimistic attitude is more conducive to the recovery from the disease.
Will having hepatitis B antibodies lead to liver cancer?
Firstly, there is no necessary connection between liver cancer and antibodies, but if a patient has hepatitis B antibodies, then the chance of this patient contracting hepatitis B is very small. Relatively speaking, since hepatitis B can develop into liver cancer, having positive hepatitis B antibodies might reduce the chance of developing liver cancer. However, there are many types of liver cancer, and its causes are varied, including hepatitis B, hepatitis C, and other factors.