Is primary liver cancer hereditary?

Written by Peng Li Bo
Oncology
Updated on November 24, 2024
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Primary liver cancer is usually not hereditary, but the reason why it tends to appear in families in China is mainly due to the widespread infection of hepatitis B virus, which then leads to a significant correlation with hepatic cirrhosis caused by hepatitis B. It is well known that the hepatitis B virus is contagious and can easily be transmitted within families and from mother to child. Therefore, it is not uncommon to see several cases of liver cancer within the same family, indicating a familial aggregation. Another factor is related to dietary habits, for example, the infection of aflatoxin, which is mainly found in moldy peanuts. If the dietary habits within a family are similar, then, of course, the likelihood of occurrence is certainly higher.

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Written by Sun Wei
Surgical Oncology
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The difference between primary liver cancer and metastatic liver cancer

Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to cancers that start in other parts of the body and then spread to the liver through lymphatic and blood circulation, among other routes. Another difference is that primary liver cancer is more likely to be a single lesion, while metastatic liver cancer generally involves multiple lesions. Regarding the differences between primary and metastatic liver cancer, their treatment methods also differ. For primary liver cancer, interventional chemotherapy or surgery, such as hepatic lobectomy, can be performed if the tumor is small. In contrast, metastatic liver cancer usually involves multiple lesions, making surgery alone challenging. Additionally, the primary tumor also requires treatment.

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Written by Peng Li Bo
Oncology
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Is primary liver cancer hereditary?

Primary liver cancer is usually not hereditary, but the reason why it tends to appear in families in China is mainly due to the widespread infection of hepatitis B virus, which then leads to a significant correlation with hepatic cirrhosis caused by hepatitis B. It is well known that the hepatitis B virus is contagious and can easily be transmitted within families and from mother to child. Therefore, it is not uncommon to see several cases of liver cancer within the same family, indicating a familial aggregation. Another factor is related to dietary habits, for example, the infection of aflatoxin, which is mainly found in moldy peanuts. If the dietary habits within a family are similar, then, of course, the likelihood of occurrence is certainly higher.

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Written by Sun Wei
Surgical Oncology
49sec home-news-image

Can primary liver cancer be treated?

Primary liver cancer is also treatable. Generally, if the primary liver cancer is small and has not widely metastasized, surgical resection can be considered, mainly involving hepatectomy and lymph node dissection. Postoperative comprehensive treatment including chemotherapy and radiotherapy is also applied. For primary liver cancer, interventional chemotherapy, as well as methods like cryotherapy, microwave, and ablation can be considered to control the progression of the disease. Additionally, oral targeted therapy such as sorafenib can be used. If primary liver cancer is widely metastasized at the time of detection, there generally aren’t very effective treatment options, and the average survival period might be around six months, with poor treatment outcomes.

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Written by Sun Wei
Surgical Oncology
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What can people with primary liver cancer eat?

Primary liver cancer, commonly referred to as liver cancer, is a type of malignant tumor of the digestive system. As for diet, there are generally no specific prohibitions. However, it is recommended to stick to a light and easily digestible diet. High-protein foods and high-quality proteins, such as fish, eggs, and protein powder, are very good options. It is best to avoid spicy, pickled, smoked, or grilled foods, as these are not conducive to health. Also, any food that is clearly moldy should definitely be avoided. The main causes of primary liver cancer include infection with aflatoxin and contaminated drinking water, which are two main causes of primary liver cancer. Other causes, like hepatitis virus infections, are also major contributors to primary liver cancer.

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Written by Ye Xi Yong
Infectious Diseases
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Will Hepatitis B with e-antigen positive develop into liver cancer?

A small portion of patients with hepatitis B major yang can develop into liver cancer, but this development process is generally long. Primary liver cancer is currently the fourth most common malignant tumor in China, and the third leading cause of tumor death, seriously threatening the lives and health of our people. Primary liver cancer includes three types, of which hepatocellular carcinoma accounts for more than 85% to 90%. A large part of patients with primary liver cancer in China, most of whom have a background of chronic hepatitis B and cirrhosis.