Can alpha-fetoprotein confirm liver cancer?

Written by Du Rui Xia

Obstetrics

Updated on November 03, 2024

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Alpha-fetoprotein is a type of oncofetal antigen and a glycoprotein. It is used clinically as a highly specific marker for diagnosing primary liver cancer. However, elevated alpha-fetoprotein levels do not definitively indicate liver cancer, as although it is a tumor marker with diagnostic significance, elevated levels can also be seen in patients with liver cirrhosis or chronic hepatitis. Additionally, increased alpha-fetoprotein can occur in pregnant women or in the presence of other types of cancer, so further investigation is necessary to confirm the cause.

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Written by Liu Liang

Oncology

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What to do if vomiting occurs in liver cancer?

Liver cancer is divided into two main pathological types, the first being hepatocellular carcinoma, which is the most common, and the other being cholangiocellular carcinoma. Clinically, vomiting is also a common symptom of liver cancer. For symptomatic treatment, we can provide gastric protection and administer antiemetic drugs such as stomach comfort, but these are only symptomatic treatments and do not cure the root cause. The key is still to treat the liver cancer itself, as the symptoms will only alleviate once the cancer is under control. For advanced hepatocellular carcinoma, targeted therapies like sorafenib are available. If it is cholangiocellular carcinoma, and symptoms like vomiting and jaundice appear, which may be obstructive symptoms, then a surgical procedure in hepato-biliary surgery to drain the bile can be performed, which can also alleviate the symptoms of vomiting. (Medications should be used under the guidance of a doctor.)

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Written by Sun Wei

Surgical Oncology

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The difference between primary liver cancer and secondary liver cancer

Primary liver cancer, also commonly referred to as liver cancer, originates in the liver itself and is not transferred from other parts of the body. Secondary liver cancer occurs when the primary tumor originates in another location and then metastasizes to the liver, causing hepatic space-occupying lesions; this is referred to as secondary liver cancer. The main difference between the two types is their origin. Additionally, primary liver cancer is often solitary but may develop intrahepatic or distant metastases as the disease progresses. In cases of secondary liver cancer, multiple intrahepatic metastatic lesions may be discovered at the onset. Moreover, primary liver cancer may often display an elevated alpha-fetoprotein tumor marker, whereas this marker might be normal in secondary liver cancer.

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Written by Sun Wei

Surgical Oncology

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What can people with primary liver cancer eat?

Primary liver cancer, commonly referred to as liver cancer, is a type of malignant tumor of the digestive system. As for diet, there are generally no specific prohibitions. However, it is recommended to stick to a light and easily digestible diet. High-protein foods and high-quality proteins, such as fish, eggs, and protein powder, are very good options. It is best to avoid spicy, pickled, smoked, or grilled foods, as these are not conducive to health. Also, any food that is clearly moldy should definitely be avoided. The main causes of primary liver cancer include infection with aflatoxin and contaminated drinking water, which are two main causes of primary liver cancer. Other causes, like hepatitis virus infections, are also major contributors to primary liver cancer.

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Written by Liu Liang

Oncology

1min 9sec

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What are the early symptoms of liver cancer?

The early symptoms of liver cancer lack specificity, so in clinical practice, early-stage liver cancer is generally detected only during routine screenings or physical examinations. By the time patients present with noticeable symptoms and seek medical attention, the cancer is often in the intermediate or advanced stages, making surgical removal unlikely for most patients. The early symptoms might include non-specific signs such as fatigue. It is usually only in the intermediate or advanced stages that patients experience obvious symptoms like pain in the liver area, palpable abdominal masses, abdominal distension, weight loss, and jaundice. By the time these symptoms appear, it is typically quite late, corresponding to the intermediate or advanced stages of the disease. Early stages typically do not show specific symptoms, though some patients might experience mild abdominal pain, bloating, or fatigue, which are not very specific signs.

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Written by Sun Wei

Surgical Oncology

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The difference between primary liver cancer and metastatic liver cancer

Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to cancers that start in other parts of the body and then spread to the liver through lymphatic and blood circulation, among other routes. Another difference is that primary liver cancer is more likely to be a single lesion, while metastatic liver cancer generally involves multiple lesions. Regarding the differences between primary and metastatic liver cancer, their treatment methods also differ. For primary liver cancer, interventional chemotherapy or surgery, such as hepatic lobectomy, can be performed if the tumor is small. In contrast, metastatic liver cancer usually involves multiple lesions, making surgery alone challenging. Additionally, the primary tumor also requires treatment.