Gallbladder cancer

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can gallbladder cancer with liver metastasis be treated?

If a gallbladder cancer patient experiences liver metastasis, aggressive treatment can be applied, but it can only be symptomatic treatment and cannot achieve a cure. Gallbladder cancer is a type of malignancy with a high degree of malignancy, prone to metastasis to other parts, and with very poor treatment outcomes. If liver metastasis occurs, the condition is severe and has reached the middle to late stages. Treatment cannot involve surgical removal at this time. Instead, active management should be employed to improve quality of life and better control the disease, though it cannot be cured. When gallbladder cancer patients experience liver metastasis, symptoms may include pain in the liver area, abnormal liver function, hypoalbuminemia, ascites, and other clinical symptoms. At this time, symptomatic treatment should be actively pursued to better maintain the patient's life and improve quality of life.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Is jaundice a sign of advanced gallbladder cancer?

If a patient with gallbladder cancer exhibits jaundice, it does not necessarily mean the cancer is in its late stages. As the cancer grows, it may compress the bile duct, leading to obstructive jaundice. This can result in lighter-colored stools, darker urine, and yellowing of the skin and mucous membranes, and even cause itchy skin. Therefore, it is not necessarily indicative of advanced gallbladder cancer. Of course, if a patient with late-stage gallbladder cancer experiences liver metastasis, this might also manifest as yellowing of the skin and mucous membranes throughout the body. At this point, it is necessary to carry out thorough examinations, common tests including abdominal CT scans and ultrasounds, which can better assess the condition. If metastasis is present, even systemic chemotherapy might be required to achieve a better treatment outcome.

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Written by Li Hu Chen
Imaging Center
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Gallbladder cancer B-ultrasound manifestations

Gallbladder cancer can be diagnosed using ultrasound. On ultrasound, this type of gallbladder cancer can generally be divided into three types. One type is the thick-walled gallbladder cancer, which appears as uneven thickening of the gallbladder wall, resembling thick, non-elastic leather. The second type is the mass-forming type, which is relatively easier to diagnose. It appears as a solid mass taking over the entire gallbladder, often invading the nearby liver, and the normal shape of the gallbladder has disappeared. The third type is the intraluminal type, where on ultrasound, you can see the tumor attached to the gallbladder wall, which is relatively wider and larger.

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Written by Shen Jiang Chao
Radiology
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Can gallbladder cancer be detected by ultrasound?

Gallbladder cancer can also be detected by ultrasound, which is the preferred imaging method for diagnosing hepatobiliary diseases. Ultrasound can detect space-occupying lesions in hepatobiliary diseases early on. It is sensitive enough to detect lesions as small as one centimeter, or even a few millimeters. In the case of space-occupying lesions of the gallbladder, particularly gallbladder cancer, there are no particularly obvious signals on ultrasound. Ultrasound of the gallbladder is merely used as a screening tool, not as a definitive diagnostic method. If gallbladder cancer is suspected, further investigations such as MRI or enhanced CT are generally required, but the final diagnosis still relies on pathology.

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Written by Shen Jiang Chao
Radiology
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The main manifestations of gallbladder cancer on MRI

Gallbladder cancer is more common in females and is generally believed to be associated with chronic stimulation from chronic cholecystitis and gallstones. On MRI, gallbladder cancer can be categorized into several types based on case classification and growth patterns: first, the infiltrative type; second, the nodular type; third, the mass-forming type; and fourth, the obstructive type. Regardless of the pathological type of gallbladder cancer, the tumor tissue appears as a heterogeneous low signal on T1 and a heterogeneous high signal on T2. After enhancement, the tumor shows heterogeneous enhancement. If there is invasion into the liver, the boundary with liver tissue is unclear. MRI has significant advantages in assessing invasion of adjacent organs and metastasis, and can provide great value for surgery or treatment planning.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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What foods can someone with gallbladder cancer eat?

Patients with gallbladder cancer should pay attention to the following points in their diet: 1. Patients with gallbladder cancer should avoid spicy and irritating foods, such as chili peppers, barbecue, and garlic. They should primarily consume a light diet, eat more fresh vegetables and fruits, as these are rich in vitamins and can promote gastrointestinal motility, maintain smooth bowel movements, and prevent intestinal obstruction. 2. The diet of gallbladder cancer patients should also include some foods high in protein, such as eggs, lean meat, and fish, because these foods can supplement the albumin needed by the human body, enhance the patient's resistance, and thus be beneficial for the recovery of the condition.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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What should I do if gallbladder cancer causes itchy skin?

Gallbladder cancer patients may experience skin itching, as they often develop secondary obstructive jaundice. This can lead to lighter stool color, darker urine color, yellowing of the skin and mucous membranes, and generalized itching. For treatment, surgery should be performed for better therapeutic outcomes. Although medications to reduce jaundice can be used for symptomatic treatment, surgery is generally advocated, especially for early-stage gallbladder cancer patients without significant metastasis, where early surgical removal can significantly improve prognosis. Additionally, since malignant tumors are a consumptive disease, it is advisable for patients to consume a diet high in protein, such as eggs, lean meat, and fish, to supplement the proteins needed by the body and enhance the patient's immunity.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can gallbladder cancer be detected through blood tests?

Blood tests generally cannot detect gallbladder cancer because there are no specific markers in the blood tests for gallbladder cancer. Although some tumor markers may be significantly elevated, they are not specific. Therefore, diagnosis of gallbladder cancer can be refined through abdominal CT, color ultrasound, and if necessary, puncture tissue for pathological examination to confirm the nature. Once diagnosed with gallbladder cancer, surgery should be performed as soon as possible because gallbladder cancer is a highly malignant, rapidly developing, and poor prognosis malignancy. It is important to pay attention to it and handle it promptly to improve the prognosis and potentially extend the patient’s life.

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Written by Shen Jiang Chao
Radiology
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MRI manifestations of gallbladder cancer

The manifestations of gallbladder cancer on MRI primarily include significant thickening of the gallbladder wall or a mass within the gallbladder. Generally, it appears as low signal on T1-weighted images and high signal on T2-weighted images. After enhancement, the lesion shows obvious enhancement. If the lesion is large, necrosis may occur internally. Since the gallbladder is close to the liver, if abnormal signals are found in the liver, intrahepatic metastasis should be considered, which further confirms the possibility of gallbladder cancer. Additionally, gallbladder cancer can also invade the nearby bile ducts, causing dilation of the bile ducts, as well as local or distant lymph node metastasis.

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Written by Li Hu Chen
Imaging Center
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Can cholecystitis be detected by color ultrasound?

If there is gallbladder cancer, usually an ultrasonography of the liver and gallbladder or the upper abdomen can detect it. Conditions such as gallbladder cancer or liver cancer are often initially discovered and diagnosed through ultrasound. Of course, the final confirmation of diagnosis is usually achieved through pathological examination after surgery. However, in terms of initial diagnosis, it is very common to identify these conditions through ultrasound. Gallbladder cancer typically presents certain characteristic changes, such as obvious thickening of the gallbladder wall, extensive thickening including sclerosis, and significant soft tissue mass growth extending to and adhering to the liver, which are strong indicators of gallbladder cancer. Additionally, a large polyp may be seen inside the gallbladder, and surgical removal at this stage may diagnose early gallbladder cancer.