The main manifestations of gallbladder cancer on MRI

Written by Shen Jiang Chao
Radiology
Updated on September 14, 2024
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Gallbladder cancer is more common in females and is generally believed to be associated with chronic stimulation from chronic cholecystitis and gallstones. On MRI, gallbladder cancer can be categorized into several types based on case classification and growth patterns: first, the infiltrative type; second, the nodular type; third, the mass-forming type; and fourth, the obstructive type. Regardless of the pathological type of gallbladder cancer, the tumor tissue appears as a heterogeneous low signal on T1 and a heterogeneous high signal on T2. After enhancement, the tumor shows heterogeneous enhancement. If there is invasion into the liver, the boundary with liver tissue is unclear. MRI has significant advantages in assessing invasion of adjacent organs and metastasis, and can provide great value for surgery or treatment planning.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Is targeted therapy or immunotherapy better for gallbladder cancer?

The treatment of gallbladder cancer cannot be judged as whether targeted therapy or immunotherapy is better, but should be analyzed based on the specific condition of the disease. For early-stage gallbladder cancer patients, if no metastasis has occurred, the best treatment at this time is primarily surgical removal. Early-stage surgical removal can achieve a cure, and regular postoperative ultrasound checks to monitor the disease progression are sufficient. However, if the gallbladder cancer progresses to a late stage, there might be metastasis to other parts of the body, corresponding symptoms appear, and the disease progresses rapidly. The opportunity for surgical treatment may have been missed, and only systemic chemotherapy or other comprehensive treatments are available to alleviate symptoms.

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Written by Liu Wu Cai
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Can gallbladder cancer with liver metastasis be treated?

If a gallbladder cancer patient experiences liver metastasis, aggressive treatment can be applied, but it can only be symptomatic treatment and cannot achieve a cure. Gallbladder cancer is a type of malignancy with a high degree of malignancy, prone to metastasis to other parts, and with very poor treatment outcomes. If liver metastasis occurs, the condition is severe and has reached the middle to late stages. Treatment cannot involve surgical removal at this time. Instead, active management should be employed to improve quality of life and better control the disease, though it cannot be cured. When gallbladder cancer patients experience liver metastasis, symptoms may include pain in the liver area, abnormal liver function, hypoalbuminemia, ascites, and other clinical symptoms. At this time, symptomatic treatment should be actively pursued to better maintain the patient's life and improve quality of life.

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Written by Liu Wu Cai
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What foods can someone with gallbladder cancer eat?

Patients with gallbladder cancer should pay attention to the following points in their diet: 1. Patients with gallbladder cancer should avoid spicy and irritating foods, such as chili peppers, barbecue, and garlic. They should primarily consume a light diet, eat more fresh vegetables and fruits, as these are rich in vitamins and can promote gastrointestinal motility, maintain smooth bowel movements, and prevent intestinal obstruction. 2. The diet of gallbladder cancer patients should also include some foods high in protein, such as eggs, lean meat, and fish, because these foods can supplement the albumin needed by the human body, enhance the patient's resistance, and thus be beneficial for the recovery of the condition.

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Written by Li Hu Chen
Imaging Center
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Can cholecystitis be detected by color ultrasound?

If there is gallbladder cancer, usually an ultrasonography of the liver and gallbladder or the upper abdomen can detect it. Conditions such as gallbladder cancer or liver cancer are often initially discovered and diagnosed through ultrasound. Of course, the final confirmation of diagnosis is usually achieved through pathological examination after surgery. However, in terms of initial diagnosis, it is very common to identify these conditions through ultrasound. Gallbladder cancer typically presents certain characteristic changes, such as obvious thickening of the gallbladder wall, extensive thickening including sclerosis, and significant soft tissue mass growth extending to and adhering to the liver, which are strong indicators of gallbladder cancer. Additionally, a large polyp may be seen inside the gallbladder, and surgical removal at this stage may diagnose early gallbladder cancer.

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Early symptoms and warning signs of gallbladder cancer.

Patients with early-stage gallbladder cancer generally do not display specific symptoms or obvious precursors. Some patients may experience digestive symptoms such as abdominal bloating, indigestion, nausea, and vomiting, but these are often overlooked. Thus, by the time gallbladder cancer is diagnosed, it is usually at an advanced stage, where the pain becomes significant and is one of the main reasons patients seek medical attention. Additionally, some patients may experience weight loss and even develop cachexia. Gallbladder cancer is a highly malignant tumor with rapid progression and a tendency to metastasize to other parts of the body, resulting in a very poor prognosis. Therefore, once diagnosed with gallbladder cancer, it is crucial to complete relevant examinations, rule out any contraindications for surgery, and proceed with surgical removal as soon as possible.