Is targeted therapy or immunotherapy better for gallbladder cancer?

Written by Liu Wu Cai
Hepatobiliary Surgery
Updated on November 17, 2024
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The treatment of gallbladder cancer cannot be judged as whether targeted therapy or immunotherapy is better, but should be analyzed based on the specific condition of the disease.

For early-stage gallbladder cancer patients, if no metastasis has occurred, the best treatment at this time is primarily surgical removal. Early-stage surgical removal can achieve a cure, and regular postoperative ultrasound checks to monitor the disease progression are sufficient.

However, if the gallbladder cancer progresses to a late stage, there might be metastasis to other parts of the body, corresponding symptoms appear, and the disease progresses rapidly. The opportunity for surgical treatment may have been missed, and only systemic chemotherapy or other comprehensive treatments are available to alleviate symptoms.

Other Voices

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can people with gallbladder cancer eat lamb?

Patients with gallbladder cancer can appropriately eat mutton, as mutton is a food high in protein, which can supplement the albumin needed by the human body and better improve the patient's resistance. However, patients with gallbladder cancer may experience discomfort such as pain in the upper right abdomen and may also encounter digestive symptoms like indigestion and bloating. Therefore, it is recommended for gallbladder cancer patients to consume foods that are easy to digest, which can reduce the burden on the gastrointestinal tract and facilitate recovery. Although mutton can be consumed, it should be eaten in small, frequent meals to prevent complications such as intestinal obstruction. Additionally, for the treatment of gallbladder cancer, surgical removal should be used as early as possible to achieve a cure, with earlier detection and treatment likely leading to a relatively better prognosis.

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Written by Shen Jiang Chao
Radiology
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Gallbladder cancer CT manifestations

Gallbladder cancer commonly occurs in females, and its causes may be related to chronic and long-term irritation from cholecystitis and gallstones. On a CT scan, based on the tumor's pathological classification and growth patterns, it can be divided into the following types: The first type is the infiltrative type, which is characterized by irregular thickening of the gallbladder wall, usually greater than 1 cm, with a rough edge, and significant enhancement is seen after contrast enhancement. The second type is the mass-forming type, which presents as a large soft tissue mass filling the gallbladder, also showing significant enhancement after injection of contrast agent. The third type is the nodular type, which presents as either single or multiple nodules that protrude into the gallbladder cavity, appearing papillary or cauliflower-like. The fourth type is the obstructive type, generally a tumor at the neck of the gallbladder, causing obstruction of the common bile duct.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Early symptoms and warning signs of gallbladder cancer.

Patients with early-stage gallbladder cancer generally do not display specific symptoms or obvious precursors. Some patients may experience digestive symptoms such as abdominal bloating, indigestion, nausea, and vomiting, but these are often overlooked. Thus, by the time gallbladder cancer is diagnosed, it is usually at an advanced stage, where the pain becomes significant and is one of the main reasons patients seek medical attention. Additionally, some patients may experience weight loss and even develop cachexia. Gallbladder cancer is a highly malignant tumor with rapid progression and a tendency to metastasize to other parts of the body, resulting in a very poor prognosis. Therefore, once diagnosed with gallbladder cancer, it is crucial to complete relevant examinations, rule out any contraindications for surgery, and proceed with surgical removal as soon as possible.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can gallbladder cancer with liver metastasis be treated?

If a gallbladder cancer patient experiences liver metastasis, aggressive treatment can be applied, but it can only be symptomatic treatment and cannot achieve a cure. Gallbladder cancer is a type of malignancy with a high degree of malignancy, prone to metastasis to other parts, and with very poor treatment outcomes. If liver metastasis occurs, the condition is severe and has reached the middle to late stages. Treatment cannot involve surgical removal at this time. Instead, active management should be employed to improve quality of life and better control the disease, though it cannot be cured. When gallbladder cancer patients experience liver metastasis, symptoms may include pain in the liver area, abnormal liver function, hypoalbuminemia, ascites, and other clinical symptoms. At this time, symptomatic treatment should be actively pursued to better maintain the patient's life and improve quality of life.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can gallbladder cancer be detected by cancer embryonic antigen test?

The use of cancer embryo antigen in patients with gallbladder cancer has certain reference value, but it is not absolute. Patients with gallbladder cancer typically show a significant increase in embryonic antigen. Gallbladder cancer is difficult to diagnose early as it generally does not show specific symptoms. Some patients may experience mild discomfort in the upper right abdomen, but this is often overlooked or misdiagnosed as other diseases, such as chronic gastritis. Therefore, once diagnosed with gallbladder cancer, it is usually already at a middle to late stage. Although the cancer embryo antigen in tumor marker tests of gallbladder cancer patients can be elevated, this is not absolute. Therefore, when discomfort in the upper right abdomen occurs, further comprehensive examinations like color ultrasound, CT, and other related tests are necessary to differentiate it.