Cervical cancer

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Written by Li Lin
Obstetrics and Gynecology
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How is cervical cancer checked?

Cervical cancer screening begins with testing for the human papillomavirus (HPV) and a cervical cytology smear test. If abnormalities are found in these tests, a colposcopy examination is needed. Under colposcopy, suspicious cancerous areas are selected for a cervical biopsy, and the cervical tissue is sent for pathological sections. Based on the results of the pathology sections, it is determined whether the condition is a precancerous lesion of the cervix or cervical cancer. If cervical cancer is present, a clinical doctor must perform a gynecological internal examination to determine the stage of the cervical cancer, and then choose a treatment plan.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Can cervical cancer be cured?

Cervical cancer can be treated with options including surgery, radiotherapy, and chemotherapy. For Stage 1A1 cervical cancer, a conization surgery can be chosen; for stages from 1A2 up to before 2B, a radical hysterectomy with bilateral adnexectomy and pelvic lymphadenectomy can be selected; if it is Stage 2B, where the cancer has spread to the parametrium, it is recommended to first undergo chemotherapy as preoperative neoadjuvant therapy to reduce the tumor size before proceeding with surgery; if the cancer has progressed to Stage 3A1 and beyond, radiotherapy or chemotherapy is recommended. In summary, surgical treatment can be chosen for cervical cancer before Stage 2B; if it is Stage 2B or later, involving the parametrium or the lower third of the vagina, surgery is generally not an option, and the treatment usually involves radiotherapy or chemotherapy.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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Symptoms of cervical cancer

The most typical early symptom of cervical cancer is usually contact bleeding during intercourse. Clinically, once contact bleeding occurs, it is essential to go to the hospital for cervical cancer screening as soon as possible, generally involving a cervical TCT and HPV test. These two tests can initially screen for the presence of cervical cancer and precancerous lesions. If it has progressed to the stage of cervical cancer, there may be a large amount of vaginal discharge with a foul smell, and severe cases can have symptoms like bleeding and abdominal pain. Therefore, patients with cervical cancer must undergo relevant cervical examinations at the hospital. If it is indeed cervical cancer, treatment options should be selected based on the stage of the disease to treat the symptoms accordingly. Hence, if there is any irregular vaginal bleeding, it is critical to go to the hospital for the relevant cancer screening.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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How long does it take for cervical cancer to develop?

The causes of cervical cancer are now clear; it is caused by an infection with the HPV virus. Generally, this virus needs to be carried for more than two to three years before it can infect and develop into cervical cancer. There is a process of carcinogenesis where normal epithelial tissue transforms into cervical intraepithelial neoplasia. If the HPV infection is not treated and continues, it could lead to cervical cancer. Thus, the development process is relatively long, typically requiring two to three years. It is recommended that sexually active women undergo cervical cancer screening to check for any pathological changes in the cervix, including HPV, TCT, and colposcopy examinations.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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Is cervical hypertrophy cervical cancer?

In clinical practice, most cases of cervical hypertrophy are not cervical cancer, but normal women do not have cervical hypertrophy. It is recommended that patients who suspect cervical hypertrophy should immediately visit the obstetrics and gynecology clinic of their local hospital, undergo a gynecological color ultrasound, and a gynecological examination to determine the cause of the cervical hypertrophy. The gynecological examination mainly relies on the doctor's visual assessment of the size of the cervix, and observation of any obvious lesions on the surface of the cervix. Additionally, gynecological ultrasound can be used to identify potential lesions in parts of the cervix that are not visible to the naked eye.

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Written by Yan Qiao
Obstetrics and Gynecology
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Does cervical cancer hurt?

For patients with cervical cancer, the most common clinical manifestations are bleeding during sexual intercourse and irregular vaginal bleeding. Patients who have undergone menopause may also experience irregular vaginal bleeding post-menopause, and some patients may not show any clinical signs at a very early stage. As the cancer progresses, and when it invades nearby organs and metastasizes, it may cause lower abdominal distension and pain, and even more severe pain if the metastatic organs compress nerves or directly invade areas containing nerves.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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How is cervical cancer screened?

Cervical cancer screening is a routine gynecological examination item for married women and women who are sexually active. Cervical cancer screening includes TCT (ThinPrep Cytologic Test) and HPV (Human Papillomavirus) tests. The TCT is a cytological examination of the cervix to determine if there are any cervical lesions based on cell morphology. HPV is the human papillomavirus, and its presence is a high-risk factor for cervical cancer. Therefore, cervical cancer screening consists of both TCT and HPV tests. If abnormalities are found in either test, a cervical biopsy may be necessary to confirm the presence of cervical lesions. It is best to conduct these tests between three to seven days after the end of menstruation.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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latent period of cervical cancer

The latency period for cervical cancer is generally five to ten years. The occurrence of cervical cancer is mainly due to exposure to the human papillomavirus (HPV) in the body. Typically, this virus persists and replicates within the body, leading to cervical cancer and precancerous lesions. From the initial virus infection to the development of cervical cancer, it usually takes a vast majority about five to ten years. Furthermore, different types of virus infections lead to varying probabilities of cervical cancer. In general, if the infection involves types 16 and 18 of the virus, the likelihood of developing cervical cancer is particularly high. Therefore, if one is infected with HPV types 16 and 18, it is crucial to undergo a cervical TCT test. If necessary, a cervical biopsy is generally performed under colposcopy, followed by treatment based on the examination results. Thus, to prevent cervical cancer, it is essential for women to undergo regular annual cervical cancer screening.

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Written by Li Shun Hua
Obstetrics and Gynecology
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Can a cervical biopsy detect cervical cancer?

Cervical biopsy can detect cervical cancer as long as the altered tissue is collected. However, some people have a type 3 transformation zone in the cervix, making it difficult to obtain the altered tissue, and in these cases, cervical scraping is needed. Therefore, it is best to perform the biopsy under colposcopic examination and conduct a cervical canal scraping at the same time. If there is cervical cancer, it can be detected, and generally, it will not be missed.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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Cervical cancer is divided into several stages.

Cervical cancer is categorized into four stages based on the extent of the cancer lesion, with different stages receiving different treatments clinically. Stage I cervical cancer is the earliest stage, while stage IV cervical cancer is the latest stage, often invading organs beyond the reproductive system. Clinically, early-stage cervical cancer is primarily treated with surgical resection, followed by postoperative radiotherapy and chemotherapy to reduce the likelihood of cancer recurrence. In contrast, late-stage cervical cancer is treated primarily with radiotherapy and chemotherapy.