latent period of cervical cancer

Written by Zhang Xiu Rong
Obstetrics and Gynecology
Updated on November 05, 2024
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The latency period for cervical cancer is generally five to ten years. The occurrence of cervical cancer is mainly due to exposure to the human papillomavirus (HPV) in the body. Typically, this virus persists and replicates within the body, leading to cervical cancer and precancerous lesions. From the initial virus infection to the development of cervical cancer, it usually takes a vast majority about five to ten years. Furthermore, different types of virus infections lead to varying probabilities of cervical cancer. In general, if the infection involves types 16 and 18 of the virus, the likelihood of developing cervical cancer is particularly high. Therefore, if one is infected with HPV types 16 and 18, it is crucial to undergo a cervical TCT test. If necessary, a cervical biopsy is generally performed under colposcopy, followed by treatment based on the examination results. Thus, to prevent cervical cancer, it is essential for women to undergo regular annual cervical cancer screening.

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Cervical Cancer Staging Criteria

For the staging of cervical cancer, the staging criteria of the International Federation of Gynecology and Obstetrics (FIGO) are now adopted. Staging should be done before treatment, and since the FIGO staging of the cervix mainly relies on the examination of the pelvis, it is emphasized that the pelvic examination must be performed by two senior gynecologic oncologists. The staging primarily involves assessing the size of the cervical lesion, particularly the measurement of endophytic tumors, parametrial tissue infiltration, and the status of pelvic lymph nodes. However, these stages mainly rely on radiological examinations, primarily magnetic resonance imaging (MRI), to provide objective data for staging.

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Precursors of cervical cancer

The occurrence and development of the cervix is a process from quantitative to qualitative change, evolving gradually to a sudden shift over a long period. The precursor might be the heterotypic zone of the cervix, which is a common site for abnormalities. During the formation of this heterotypic zone, cervical epithelial metaplasia is relatively active, and, compounded by infection with the human papillomavirus and further stimulated by external carcinogens, immature or proliferative squamous epithelial cells may exhibit gradual changes or atypical hyperplasia, potentially leading to sarcomatoid changes in the cervical epithelium. This might be a precursor sign.

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How to prevent cervical cancer

How to prevent cervical cancer: Firstly, it is very important to prevent infection with the human papillomavirus (HPV). So, how can one prevent HPV infection? First, in choosing sexual partners, one should select a healthy male, generally a steady one, and avoid relationships with men who have penile cancer, prostate cancer, or whose ex-wife had cervical cancer, as these men are considered high-risk, and the women they come into contact with are also at increased risk of developing cervical cancer. Secondly, we should pay attention to personal hygiene. Thirdly, one should enhance their physical constitution to prevent viral infections and to maintain cleanliness. Fourthly, attention should be given to prevention of other contributing factors, such as early childbirth. Therefore, it is necessary to choose an appropriate age for childbirth. Multiple births are also related to cervical cancer, so if pregnant, one should avoid miscarriage and multiple dilation and curettage procedures. Fifthly, adhere to a healthy and reasonable diet, and avoid smoking and drinking alcohol.

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Does cervical cancer hurt?

For patients with cervical cancer, the most common clinical manifestations are bleeding during sexual intercourse and irregular vaginal bleeding. Patients who have undergone menopause may also experience irregular vaginal bleeding post-menopause, and some patients may not show any clinical signs at a very early stage. As the cancer progresses, and when it invades nearby organs and metastasizes, it may cause lower abdominal distension and pain, and even more severe pain if the metastatic organs compress nerves or directly invade areas containing nerves.

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Self-exam method for cervical cancer

There aren't many methods for self-examination of cervical cancer. If symptoms such as vaginal bleeding or discharge occur, it is crucial to visit a hospital for a gynecological examination promptly. Of course, the diagnosis of cervical cancer should still rely on the examination by specialist doctors at hospitals. There are cytological examinations of cervical scrapings available, as well as examinations of cervical and endocervical tissue to confirm whether it is cervical cancer or not. Particularly, the examination of cervical and endocervical tissue is the main basis for confirming cervical cancer. Therefore, we should still undertake pathological examinations to confirm whether it is cervical cancer or not, rather than relying solely on self-examination to diagnose cervical cancer.