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Li Fang Fang
Hematology
About me
After graduation, I have been working in the Hematology Department at Kaifeng Central Hospital, engaging in clinical work. I have gained certain clinical experience in common diseases in the field of hematology, and have also assisted other clinical departments in auxiliary treatments.
Proficient in diseases
Specializes in common diseases of hematology, such as leukemia, hemophilia, anemia, lymphoma, thrombocytopenia, tetanus, hypoglycemia, aplastic anemia, neonatal hemorrhage, vitamin deficiencies, and other autoimmune diseases.
Voices
Can aplastic anemia have children?
Acute aplastic anemia, after effective immunotherapy and discontinuation of medication for more than two years, or after hematopoietic stem cell transplantation and discontinuation of medication for more than two years, it is possible to have children. In cases of chronic aplastic anemia, due to long-term oral intake of immunosuppressants and hematopoietic stimulants, having children is not advised. However, if immunosuppressants and hematopoietic drugs are effective and discontinued for more than two years, and blood levels are acceptable, then it is possible to have children.
What to eat for aplastic anemia
Patients with aplastic anemia should eat light, easily digestible foods, and soft diet, avoiding too hard foods, and foods with spines or bones to prevent these foods from scratching the mucous membrane of the digestive tract and causing gastrointestinal bleeding. Additionally, patients with aplastic anemia must also take medications to control the progression of the disease, the related medications mainly include immunosuppressants, such as cyclosporine, as well as hematopoietic stimulants and traditional Chinese medicine formulations. Hematopoietic drugs include androgens, such as danazol and stanozolol, etc., and traditional Chinese medicines include compound alumite pills, rejuvenating blood tablets, etc. (Please use specific medications under the guidance of a doctor, and do not self-medicate.)
Which department should I go to for anemia?
Anemia is classified as a hematological disease and requires further diagnosis and treatment in the department of hematology. In severe cases of anemia, the body can be in a state of ischemia and hypoxia, which can induce the occurrence of acute cardiovascular and cerebrovascular diseases, such as acute angina and cerebral thrombosis. Therefore, patients with acute anemia need to have red blood cell transfusions to support treatment and correct the anemia. If the anemia is not severe, red blood cell transfusion is not necessary, but it is important to complete tests like anemia indicators, bone marrow aspiration, and bone marrow biopsy to further clarify the cause of the anemia and treat it accordingly.
Does aplastic anemia cause fever?
Aplastic anemia itself does not cause fever in patients; however, individuals with aplastic anemia experience a decrease in all blood cells, including white blood cells, red blood cells, and platelets. A significant reduction in white blood cells, such as in a state of neutropenia, can lower a patient's resistance to infections, which makes it easy for secondary infections to occur and thus induce fever. Furthermore, in cases of severe anemia, severe aplastic anemia can also lead to the occurrence of low-grade fever in patients. On the other hand, a reduction in platelets generally does not cause fever. Therefore, when a patient with aplastic anemia has a fever, it is important to determine the cause of the fever.
Can anemia cause tinnitus?
Anemia can cause tinnitus. When anemia is severe, various organs of the body are in a state of ischemia and hypoxia. The nervous system can exhibit symptoms such as dizziness, headaches, and a feeling of heaviness in the head, as well as tinnitus. At this point, infusing red blood cells to correct the anemia can alleviate symptoms like tinnitus. It is also important to actively seek the underlying causes of the anemia. Anemia can be categorized based on the size of red blood cells into microcytic hypochromic anemia, normocytic anemia, and macrocytic anemia. Microcytic hypochromic anemia is commonly seen in chronic disease anemia and iron deficiency anemia, normocytic anemia is commonly found in conditions such as leukemia, multiple myeloma, and acute blood loss anemia, while macrocytic anemia is typical in megaloblastic anemia and myelodysplastic syndromes.
Is aplastic anemia contagious?
Aplastic anemia is not contagious and has a minor hereditary factor, meaning that if a family member has aplastic anemia, it is generally not inherited by the next generation. The cause of aplastic anemia is still unclear, but possible reasons include: 1. Damage to hematopoietic stem cells. After the hematopoietic stem cells are damaged, it leads to limited stem cell proliferation and reduced hematopoiesis. 2. Damage to the hematopoietic microenvironment. Damage to the hematopoietic microenvironment can lead to changes that disrupt the regeneration of hematopoietic stem cells. 3. Immune factors. Immune factors can cause immune damage, directly damaging hematopoietic stem cells, thereby causing bone marrow regeneration disorders.
Does leukemia cause fever?
Leukemia patients do experience fever, which can be categorized into two main types: infectious fever and tumor fever. Infectious fever occurs due to the compromised resistance and lowered immunity of leukemia patients, potentially leading to various types of infections such as pulmonary infections, skin and mucous membrane infections, digestive system infections, urinary system infections, etc. Tumor fever, on the other hand, occurs in the late stages of leukemia and is caused by the abnormal proliferation of leukemia cells, leading to tumor-related fever. Typically, the temperature in tumor fever does not exceed 38 degrees Celsius, with early-stage fevers responding well to treatment, but late-stage fevers showing poorer responsiveness.
How is leukemia diagnosed?
When a routine blood test suggests the possibility of leukemia, further diagnostic tests such as bone marrow aspiration, biopsy, and immunophenotyping are required to confirm the diagnosis. Leukemia can be divided into acute leukemia and chronic leukemia. Acute leukemia includes acute myeloid leukemia and acute lymphoblastic leukemia. Acute myeloid leukemia is further categorized into eight types, from M0 to M7. Acute lymphoblastic leukemia is divided into three subtypes: L1 to L3. Chronic leukemia can be divided into chronic myeloid leukemia and chronic lymphocytic leukemia.
What medicine is used for aplastic anemia?
Aplastic anemia, whether acute or chronic, primarily uses immunosuppressive agents and hematopoietic stimulants for treatment. Cyclosporine is commonly used clinically among immunosuppressants, while the medicines stimulating bone marrow hematopoiesis mainly include androgens such as danazol and stanozolol. These medications all have associated adverse reactions: immunosuppressants can lead to hypertension, hyperglycemia, impaired liver and kidney function, and gum hypertrophy, while the main adverse reactions of hematopoietic androgens are liver damage. (Please use medications under the guidance of a doctor.)
Can aplastic anemia be cured?
Aplastic anemia is divided into acute aplastic anemia and chronic aplastic anemia. Acute aplastic anemia can be cured by intensive immunotherapy or syngeneic hematopoietic stem cell transplantation. However, not all cases of acute aplastic anemia can be cured by these two treatments, with the cure rate being approximately 60%-70%. For chronic aplastic anemia, the main treatment currently is oral immunosuppressive therapy, which usually cannot cure the condition unless allogeneic hematopoietic stem cell transplantation is performed. However, if patients with chronic aplastic anemia are on oral immunosuppressive therapy, they can maintain a relatively good condition and typically do not opt for allogeneic hematopoietic stem cell transplantation.