Aplastic anemia is not contagious and has a minor hereditary factor, meaning that if a family member has aplastic anemia, it is generally not inherited by the next generation. The cause of aplastic anemia is still unclear, but possible reasons include: 1. Damage to hematopoietic stem cells. After the hematopoietic stem cells are damaged, it leads to limited stem cell proliferation and reduced hematopoiesis. 2. Damage to the hematopoietic microenvironment. Damage to the hematopoietic microenvironment can lead to changes that disrupt the regeneration of hematopoietic stem cells. 3. Immune factors. Immune factors can cause immune damage, directly damaging hematopoietic stem cells, thereby causing bone marrow regeneration disorders.