Patients with aplastic anemia are more prone to oral ulcers. Aplastic anemia is a type of bone marrow failure syndrome, where there is a decrease in white blood cells, red blood cells, and platelets in the peripheral blood to various extents. Long-term anemia can lead to mucosal ischemia and hypoxia. The reduction in white blood cells weakens the mucosal barrier's protective function, making it susceptible to bacterial invasion and thus prone to oral ulcers. Additionally, patients with anemia often have poor diets over long periods, leading to a deficiency in various vitamins, which is another reason why they are prone to oral ulcers. If symptoms like joint pain are present along with oral ulcers, further rheumatological and immunological tests should be conducted to rule out rheumatic and immune system diseases.