Can aplastic anemia be cured?

Written by Li Fang Fang
Hematology
Updated on September 20, 2024
00:00
00:00

Aplastic anemia is divided into acute aplastic anemia and chronic aplastic anemia. Acute aplastic anemia can be cured by intensive immunotherapy or syngeneic hematopoietic stem cell transplantation. However, not all cases of acute aplastic anemia can be cured by these two treatments, with the cure rate being approximately 60%-70%. For chronic aplastic anemia, the main treatment currently is oral immunosuppressive therapy, which usually cannot cure the condition unless allogeneic hematopoietic stem cell transplantation is performed. However, if patients with chronic aplastic anemia are on oral immunosuppressive therapy, they can maintain a relatively good condition and typically do not opt for allogeneic hematopoietic stem cell transplantation.

Other Voices

doctor image
home-news-image
Written by Li Fang Fang
Hematology
59sec home-news-image

What medicine is used to treat aplastic anemia?

Aplastic anemia is divided into acute aplastic anemia and chronic aplastic anemia. Patients with acute aplastic anemia require intensified immunotherapy or allogeneic hematopoietic stem cell transplantation from a sibling match. Intensified immunotherapy involves the simultaneous use of anti-thymocyte globulin (ATG) and cyclosporine. The main treatments for chronic aplastic anemia are immunosuppressive therapy and stimulative hematopoiesis therapy. Immunotherapy primarily involves oral administration of cyclosporine; stimulative hematopoiesis therapy may include oral administration of Chinese patent medicines such as Zao Zeng Xue Pian, and danazol, an anabolic steroid. (Medications should be used under the guidance of a doctor based on the specific circumstances.)

doctor image
home-news-image
Written by Zhang Xiao Le
Hematology
44sec home-news-image

Can patients with aplastic anemia drink corn silk water?

Patients with aplastic anemia can drink corn silk tea, but corn silk tea has no therapeutic effect on aplastic anemia. Aplastic anemia is caused by various causes and mechanisms leading to bone marrow failure, mainly characterized by decreased bone marrow hematopoietic function, decreased total blood cells, and the resulting anemia, bleeding, and infection syndrome. The pathogenesis of aplastic anemia is not clear, mainly due to immune abnormalities. The treatment is mainly the use of immunosuppressants such as cyclosporine and hematopoietic agents, primarily androgens. Corn silk tea does not have a therapeutic effect on the mechanisms of this disease.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
59sec home-news-image

Does aplastic anemia cause fever?

Aplastic anemia itself does not cause fever in patients; however, individuals with aplastic anemia experience a decrease in all blood cells, including white blood cells, red blood cells, and platelets. A significant reduction in white blood cells, such as in a state of neutropenia, can lower a patient's resistance to infections, which makes it easy for secondary infections to occur and thus induce fever. Furthermore, in cases of severe anemia, severe aplastic anemia can also lead to the occurrence of low-grade fever in patients. On the other hand, a reduction in platelets generally does not cause fever. Therefore, when a patient with aplastic anemia has a fever, it is important to determine the cause of the fever.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
49sec home-news-image

The main cause of aplastic anemia is.

The causes of aplastic anemia are considered to be of three types: abnormalities in hematopoietic stem cells, abnormalities in the bone marrow microenvironment, and abnormalities in immune factors. Among these, abnormalities in immune factors play a dominant role. Therefore, most patients with aplastic anemia see some improvement after receiving immunosuppressive therapy clinically. However, there is a small subset of patients with aplastic anemia for whom immunosuppressive therapy is not effective, and the causes of the disease in these patients are not well understood and may be congenital, such as congenital dyskeratosis.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
40sec home-news-image

Aplastic anemia is caused by how?

The etiology of aplastic anemia is unclear. A more classical theory is the seed, soil, and bug theory. The seed theory suggests that patients with this condition have reduced hematopoietic stem cells in the bone marrow, leading to bone marrow failure. The soil theory refers to abnormal microenvironments in the bone marrow of patients, which leads to an abnormal growth environment for stem cells and consequently hematopoietic disturbances. The bug theory, which is commonly referred to in clinical settings as immune dysfunction, plays a major role in the etiology of this condition.