Can aplastic anemia be cured?

Written by Li Fang Fang
Hematology
Updated on September 20, 2024
00:00
00:00

Aplastic anemia is divided into acute aplastic anemia and chronic aplastic anemia. Acute aplastic anemia can be cured by intensive immunotherapy or syngeneic hematopoietic stem cell transplantation. However, not all cases of acute aplastic anemia can be cured by these two treatments, with the cure rate being approximately 60%-70%. For chronic aplastic anemia, the main treatment currently is oral immunosuppressive therapy, which usually cannot cure the condition unless allogeneic hematopoietic stem cell transplantation is performed. However, if patients with chronic aplastic anemia are on oral immunosuppressive therapy, they can maintain a relatively good condition and typically do not opt for allogeneic hematopoietic stem cell transplantation.

Other Voices

doctor image
home-news-image
Written by Li Fang Fang
Hematology
39sec home-news-image

Aplastic anemia is caused by how?

Aplastic anemia currently still has an uncertain etiology. However, clinical observations have suggested that chemotherapy drugs, viral infections, and radiation exposure might be related to the occurrence and development of aplastic anemia. Regardless of the cause, these factors all involve abnormalities in immune function. Abnormal immune function leads to the occurrence and development of aplastic anemia. Therefore, immunosuppressive therapy is often effective for patients with aplastic anemia in clinical settings. (Medication use should be conducted under the guidance of a professional doctor.)

doctor image
home-news-image
Written by Li Fang Fang
Hematology
52sec home-news-image

Is aplastic anemia serious?

Whether aplastic anemia is severe depends on the specific circumstances of the aplastic anemia. Aplastic anemia can be divided into acute aplastic anemia and chronic aplastic anemia. Among them, acute aplastic anemia has a sudden onset, more severe clinical symptoms, and a higher mortality rate, so it is relatively more severe. Chronic aplastic anemia has a slower onset, and the degree of decrease in blood cells is relatively mild, also making it less severe. However, in cases of acute aplastic anemia, if intensive immunotherapy is administered, the effectiveness can reach 60%-70%, and it can be cured through hematopoietic stem cell transplantation.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
44sec home-news-image

What medicine is used for aplastic anemia?

Aplastic anemia, whether acute or chronic, primarily uses immunosuppressive agents and hematopoietic stimulants for treatment. Cyclosporine is commonly used clinically among immunosuppressants, while the medicines stimulating bone marrow hematopoiesis mainly include androgens such as danazol and stanozolol. These medications all have associated adverse reactions: immunosuppressants can lead to hypertension, hyperglycemia, impaired liver and kidney function, and gum hypertrophy, while the main adverse reactions of hematopoietic androgens are liver damage. (Please use medications under the guidance of a doctor.)

doctor image
home-news-image
Written by Li Fang Fang
Hematology
51sec home-news-image

Can aplastic anemia have children?

Acute aplastic anemia, after effective immunotherapy and discontinuation of medication for more than two years, or after hematopoietic stem cell transplantation and discontinuation of medication for more than two years, it is possible to have children. In cases of chronic aplastic anemia, due to long-term oral intake of immunosuppressants and hematopoietic stimulants, having children is not advised. However, if immunosuppressants and hematopoietic drugs are effective and discontinued for more than two years, and blood levels are acceptable, then it is possible to have children.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
1min home-news-image

What to eat for aplastic anemia

Patients with aplastic anemia should eat light, easily digestible foods, and soft diet, avoiding too hard foods, and foods with spines or bones to prevent these foods from scratching the mucous membrane of the digestive tract and causing gastrointestinal bleeding. Additionally, patients with aplastic anemia must also take medications to control the progression of the disease, the related medications mainly include immunosuppressants, such as cyclosporine, as well as hematopoietic stimulants and traditional Chinese medicine formulations. Hematopoietic drugs include androgens, such as danazol and stanozolol, etc., and traditional Chinese medicines include compound alumite pills, rejuvenating blood tablets, etc. (Please use specific medications under the guidance of a doctor, and do not self-medicate.)