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Yang Li
Endocrinology
About me
Yang Li is the associate chief physician of the Department of Endocrinology at Hunan Provincial People's Hospital. She holds a Ph.D. and serves as the research secretary of the Department of Endocrinology. She graduated with a Ph.D. in Endocrinology from Xiangya Second Hospital in 2012. She has presided over one project funded by the National Natural Science Foundation, two projects funded by the Provincial Natural Science Foundation, and one project funded by the Health Department's cadre health special subject. She has published multiple SCI papers and domestic journal articles.
Proficient in diseases
Specializing in bone metabolism, obesity, and diabetes complications.
Voices
Does leukopenia lead to leukemia?
First of all, a concept to clarify: generally, leukemia is associated with a very high white blood cell count. So, does a decrease in white blood cells lead to leukemia? There is no direct causal relationship between the two. A reduction in white blood cells generally requires an analysis of its cause—whether it is due to a decline in hematopoietic function, a deficiency in raw materials, or an increase in destruction. These situations essentially involve issues in the production factory or where they are used. We cannot say that people with reduced white blood cells will not develop leukemia, nor can it be stated in that way. They may also, over a period, exhibit a reduction in white blood cells due to certain factors. So, if there are genes causing leukemia combined with other factors, leukemia might occur, but there is no direct causation between the two.
Harms of Obesity
In the case of obesity, it is first necessary to distinguish between physiological obesity and pathological obesity. For pathological obesity, further examination of the adrenal glands is required, such as respiratory syndrome, some problems with the pituitary gland, or conditions caused by Cushing's syndrome, all of which can lead to pathological obesity. The risks associated with obesity are quite significant. Firstly, it directly causes disturbances in the body's energy metabolism, hyperlipidemia, hypertension, or other issues. Obesity can also lead to fatty liver, lipid deposition in the heart, kidneys, and other organs, resulting in corresponding organ damage. Additionally, it can cause infertility due to the deposition of fat in the ovaries, and in terms of joints, it places excessive load on the human joints, leading to various joint diseases, and consequently increasing the risks of cardiovascular diseases and sudden death risks.
Surgical treatment of obesity
Surgical treatment for obesity is applicable under certain conditions. This requires the obesity to reach a specific level, defined by indicators such as a BMI of over 35, and in the absence of severe diabetes or complications associated with diabetes. Considering surgical interventions for weight loss, these primarily involve bariatric surgeries like gastric bypass or gastroenterostomy which reduce food intake and absorption, thereby decreasing calorie absorption to achieve weight loss. While the effects of surgical weight loss are generally quite good, it can lead to some long-term postoperative complications, so careful consideration is required.
Can obesity get pregnant?
Obesity firstly needs to be differentiated, whether it is a type of physiological obesity or a pathological obesity, such as diseases of the growth gland, Cushing's syndrome, etc., which cause pathological obesity. In this case, some corresponding examinations are required for differentiation. If it is simple obesity, further tests for insulin resistance, blood glucose, blood lipids, and other metabolic indicators are necessary to determine if they are normal, as well as liver and kidney functions. If these conditions are all acceptable, pregnancy is possible. However, it is still important to monitor these indicators during pregnancy. Obesity is not an absolute contraindication for pregnancy, but of course, it is best to control the weight before getting pregnant.
Care for diabetic foot
The first fundamental step is monitoring blood glucose; good control of blood glucose levels is essential for the effective management of diabetic foot problems. Secondly, attention must be paid to the protection of the wound. It's crucial to keep the wound clean, perform regular cleaning and disinfection, and when necessary, debride necrotic tissue thoroughly. For instance, if there is a sinus tract or deep ulceration, it is essential to open the wound and ensure drainage, removing all necrotic tissue inside. Thirdly, footwear choice is critical for patients with diabetic foot; it is important to wear shoes that are loose fitting, moderately soft yet firm, and capable of evenly distributing pressure across the footbed. There are shoes specially designed for those with diabetic foot, and these can be custom-made. Other considerations include maintaining good blood pressure control and ensuring adequate nutrition to support wound healing, including sufficient protein intake, which plays a vital role in promoting wound repair.
Is a grade two thyroid cyst serious?
Thyroid cysts at Grade 2A are generally not very serious. If we consider supporting points for severity in the thyroid, finding one example is considered as first-level evidence, while finding one plus another one counts as second-level evidence. Generally speaking, once it reaches Grade 4A and above, attention needs to be paid as it suggests a malignancy, indicating a higher possibility of malignancy. If it’s below 4A, at Grade 3 and below, it typically suggests a greater likelihood of benign lesions. In such cases, it is recommended to follow up dynamically and definitely conduct an ultrasonic contrast examination.