Leukopenia can lead to fever. White blood cells are the guardians of the human body, protecting it against external invasions such as infections. When white blood cells are decreased, the patient's resistance to infections can be significantly reduced, making them particularly susceptible to infections. This can lead to fever, as often seen in hematological patients with leukopenia who frequently experience fevers due to their chronic infection states. Therefore, when leukopenia is accompanied by fever, it is advisable to seek hospital treatment as soon as possible, as proactive infection management is crucial.