Symptoms of lobular hyperplasia cancerization

Written by Lin Yang
Breast Surgery
Updated on September 02, 2024
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The symptoms of lobular hyperplasia transforming into cancer primarily include feeling a painless, solitary small lump in the breast. The lump is hard, with a rough surface, and its boundary with surrounding tissue is not clearly defined. It is not easily movable within the breast. As the lump progresses, it can invade the Cooper's ligaments, causing them to contract, and thus the skin over the lump often appears dimpled, known as the dimpling sign, which is an early sign of breast cancer. As breast cancer continues to develop, it can cause the breast to shrink, become harder, elevate the nipple, and may lead to the ducts being pulled, flattened, retracted, or even invaginated. The affected breast may also significantly enlarge over several months, causing an increase in volume and prominence.

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Written by Lin Yang
Breast Surgery
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Does lobular hyperplasia have classifications?

Breast hyperplasia grading and color Doppler mammography grading are the same: Grade 0 indicates incomplete assessment and requires further confirmation; Grade 1 is a negative result, meaning only the normal structure of the breast; Grade 2 are benign findings, indicating benign signs such as breast hyperplasia, breast cysts, and breast lipomas; Grade 3 refers to benign findings but with a 2% malignancy rate, such as fibroadenomas of the breast; Grade 4 is suspiciously malignant and biopsy is recommended; Grade 5 suggests a high likelihood of malignancy; Grade 6 is clearly malignant, needing pathological confirmation of malignancy.

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Breast Surgery
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Can grade II hyperplasia of small leaves become cancerous?

Fibrocystic change grade II generally does not become malignant. Fibrocystic change grade II refers to breast hyperplasia or benign tumors of the breast. It can be identified based on the typical symptoms of cyclic breast swelling and pain that worsens before menstruation and diminishes or disappears after menstruation. During physical examination, there are nodular masses of varying sizes accumulated inside the breast, which are firm but not hard, sometimes with tenderness. Ultrasound examinations show no masses, or mammography shows a cotton-wool appearance, which are main symptoms of breast hyperplasia, but the possibility of concurrent breast hyperplasia and breast cancer needs to be considered. On one hand, patients with significant breast hyperplasia should be closely followed up, advising them to return to the hospital for re-examination every two or three months; on the other hand, for those with obvious hyperplastic lumps or unclear boundaries in the thickened areas, it is recommended to perform a biopsy on suspicious lesions to prevent misdiagnosis.

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Can medication completely cure mammary gland hyperplasia?

Breast hyperplasia can be treated with medication, but due to the disorder of hormone levels in the body, incomplete recovery may lead to the possibility of recurrence of breast hyperplasia. Most cases of breast hyperplasia are believed to be related to endocrine disorders, causing elevated estrogen levels, and hormonal levels in the body change periodically. When the proportion of hormones in the body is unbalanced, estrogen increases, and progesterone secretion decreases, breast hyperplasia is incompletely restored, causing breast tissue proliferation. On the other hand, it may also be related to the differences in the quality and quantity of estrogen receptors in the breast parenchyma components, resulting in uneven growth in different parts of the breast.

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Will a bad mood make lobular hyperplasia worse?

Breast lobular hyperplasia can worsen with mood because it is related to elevated estrogen levels caused by endocrine disorders. External living conditions, work and life circumstances, interpersonal relationships, and various other stresses can cause neuropsychiatric factors, all of which can change the internal environment of the body. This, in turn, affects the function of the endocrine system, leading to abnormal secretion of one or several hormones. During the menstrual cycle, breast receptors and internal hormone levels change periodically. When the proportion of hormones in the body becomes unbalanced, an increase in estrogen levels and a decrease in progesterone secretion can lead to incomplete regression of breast hyperplasia after its increase, causing the exacerbation of breast hyperplasia.

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Is lobular hyperplasia grade II severe?

Second-degree mammary lobular hyperplasia refers to simple mammary hyperplasia, which is not severe and has relatively mild symptoms or conditions. Most cases do not require treatment, but regular follow-up is necessary. For cases with more pronounced symptoms, we can use traditional Chinese medicine, which alleviates pain through methods such as soothing the liver and regulating qi, as well as harmonizing the thoroughfare and conception vessels. Vitamins can also be used to support treatment, with Vitamin B, Vitamin C, and Vitamin E improving liver function, regulating metabolic hormones, and enhancing autonomic nerve functions, serving as auxiliary medication for this condition. Vitamin E also helps relieve pain. Regular follow-up examinations with ultrasound and mammography are recommended. (Please use medications under the guidance of a doctor.)