Fibrocystic change grade II generally does not become malignant. Fibrocystic change grade II refers to breast hyperplasia or benign tumors of the breast. It can be identified based on the typical symptoms of cyclic breast swelling and pain that worsens before menstruation and diminishes or disappears after menstruation. During physical examination, there are nodular masses of varying sizes accumulated inside the breast, which are firm but not hard, sometimes with tenderness. Ultrasound examinations show no masses, or mammography shows a cotton-wool appearance, which are main symptoms of breast hyperplasia, but the possibility of concurrent breast hyperplasia and breast cancer needs to be considered. On one hand, patients with significant breast hyperplasia should be closely followed up, advising them to return to the hospital for re-examination every two or three months; on the other hand, for those with obvious hyperplastic lumps or unclear boundaries in the thickened areas, it is recommended to perform a biopsy on suspicious lesions to prevent misdiagnosis.