Early symptoms of thyroid cancer

Written by Gong Chun
Oncology
Updated on September 18, 2024
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Early symptoms of thyroid cancer: First, differentiated thyroid cancer often exhibits no symptoms in its early stages, only accidentally discovered nodules that vary in size and texture on the front of the neck. Some patients are only diagnosed during routine physical exams or through imaging studies, with clinical symptoms being relatively rare. However, more symptoms and signs may appear in the later stages. Second, medullary thyroid cancer presents some unique symptoms, such as persistent diarrhea, typically watery, and a syndrome involving the endocrine system. Patients may exhibit facial flushing, elevated blood pressure, and decreased blood calcium levels, accompanied by other conditions, such as parathyroid adenomas, multiple mucosal neuromas, and pheochromocytomas, which also manifest specific symptoms.

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Written by Yan Chun
Oncology
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Will thyroid cancer spread if surgery is not performed immediately after a biopsy?

Thyroid cancer, after undergoing a fine needle biopsy, may spread if surgery cannot be performed immediately, which is a risk of the thyroid cancer biopsy. Fine needle biopsy of the thyroid is a method for obtaining histopathological results and is a gold standard for the clinical diagnosis of thyroid cancer. A biopsy is an invasive examination that causes some degree of harm to the body, hence, informed consent must be obtained from the patient before proceeding. After the biopsy, complications such as local bleeding, swelling, pain, and infection may occur, and the spread of cancer cells at the biopsy site is a significant adverse effect. Therefore, for most thyroid cancer patients, it is advisable to arrange surgery as soon as possible after a biopsy to prevent the disease from spreading.

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Written by Gong Chun
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Thyroid cancer ultrasound manifestations

The characteristics of ultrasonography for thyroid cancer include the tumor being a solid hypoechoic mass with unclear boundaries, uneven internal echoes, abundant internal blood flow, and the presence of sandy calcifications and longitudinal growth, among others. Currently, ultrasonography is the preferred method for examining thyroid nodules. It can clearly identify the number, nature, and location of thyroid nodules, as well as whether there are any abnormally enlarged lymph nodes in the neck. Ultrasonography is highly accurate in differentiating the nature of thyroid nodules, with experienced ultrasonographers reaching an accuracy rate of over 80%. However, the highest accuracy in differentiating the nature of thyroid nodules is still achieved with fine-needle aspiration cytology.

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Written by Gong Chun
Oncology
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Causes of Thyroid Cancer

Regarding the causes of thyroid cancer, they are similar to most malignant tumors. The etiology of thyroid cancer is currently unclear, but some factors have been found to be associated with the onset of thyroid cancer. The first factor is neck radiation; the thyroid is an endocrine organ that is sensitive to radiation, so radiation exposure may cause carcinogenic changes in thyroid cancer cells. The second factor is genetics; some thyroid cancers have a clear genetic predisposition, the most typical being medullary thyroid cancer, with about 25% of patients showing familial clustering, known as familial medullary thyroid cancer. The third factor is that the rapid increase in the incidence of thyroid cancer also has some reasons, with one recognized reason being advancements in early diagnostic methods, allowing for the easy detection of numerous early lesions. The fourth is iodine intake, which has been shown to be related to some benign diseases of the thyroid, but its relationship with thyroid cancer itself needs further study.

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Written by Zhao Xin Lan
Endocrinology
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Differences between the symptoms of thyroiditis and thyroid cancer

Thyroiditis, if it is acute suppurative thyroiditis, clinical manifestations include fever, local pain in the thyroid, tenderness on palpation, and a hard texture of the thyroid. Examination will show an increase in white blood cells. Subacute thyroiditis may also present with mild fever or high fever and local pain in the thyroid, but compared to suppurative thyroiditis, the increase in white blood cell levels is not as significant in subacute thyroiditis. If it is autoimmune thyroiditis, there may not be obvious symptoms clinically; there may be enlargement of the thyroid, and the thyroid may feel tougher upon palpation. As for thyroid cancer, clinically, if it does not cause hyperthyroidism or hypothyroidism, there are no specific symptoms. When the cancerous tumor is large, there may be an enlargement of the thyroid, the texture of the enlarged thyroid will be very hard, and there will be notable local adhesions. Of course, the main difference can be detected and diagnosed through an ultrasound examination.

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Is thyroid swelling malignancy the same as thyroid cancer?

Thyroid malignancy refers to thyroid cancer, but even malignant thyroid cancer generally has a good prognosis. However, it is crucial to achieve early detection, diagnosis, and treatment. It is advised to promptly visit a thyroid specialty department for comprehensive examinations, including thyroid ultrasound, evaluation of thyroid function, and related thyroid antibodies. A fine needle aspiration biopsy should be conducted for a clear pathological diagnosis, followed by immediate active treatment, primarily surgical. Thyroid cancer includes papillary thyroid cancer, follicular thyroid cancer, medullary thyroid cancer, and undifferentiated cancer. The surgery mainly involves minimally invasive and traditional methods. Post-surgery, it is recommended to perform lymph node dissection, assess the extent of metastasis, and decide whether to proceed with Iodine-131 radiotherapy. Due to the loss of thyroid function, proactive thyroid hormone replacement therapy is advised, along with dynamic monitoring of thyroid health through ultrasound and related examinations.