What is a thyroid nodule?

Written by Hu Jian Zhuo
Nephrology and Endocrinology
Updated on September 13, 2024
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The thyroid is an endocrine gland located in the neck of the human body. If some abnormal nodules appear in it, they are referred to as thyroid nodules. Based on histological classification, they can be divided into follicular type, papillary type, and mixed type. A common characteristic of these types is that they generally appear as solitary nodules with a relatively complete capsule; the tumor cells differ from the surrounding thyroid tissue; and the cellular structure inside the tumor is relatively consistent. Generally speaking, middle-aged women are the demographic most prone to developing thyroid nodules.

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Written by Zhang Jun Jun
Endocrinology
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The difference between thyroid nodules and nodular goiter

Thyroid nodules are the clinical manifestations of nodular goiter, and nodular goiter is the cause of thyroid nodules. Nodular goiter generally occurs in iodine-deficient areas, forming these partial or multiple thyroid nodules. Thyroid nodules are the clinical manifestations of nodular goiter; the nodules in the thyroid can be single or multiple and can cause abnormal thyroid function, although thyroid function can also be normal in the early stages. Therefore, when performing an ultrasound, if thyroid nodules are discovered, it is necessary to further assess thyroid function and dynamically track changes in the size of the thyroid nodules to determine whether it is nodular goiter.

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Written by Hu Jian Zhuo
Nephrology and Endocrinology
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Differentiation between benign and malignant thyroid nodules

Generally speaking, whether benign or malignant, thyroid nodules show blood flow signals. For benign nodules, blood flow signals can be seen around the perimeter, with internal blood flow no different from normal thyroid tissue. In such cases, the nodules are typically diagnosed as thyroid adenomas, and they usually appear round or oval in shape with a uniformly echoic internal substance. If liquefaction occurs, mixed or cystic changes can appear; the tumor’s capsule tends to be intact, with clear boundaries. If a nodule has abundant internal blood flow with disorganized vessel distribution and high flow velocity, showing a high-resistance flow pattern, and has relatively less peripheral blood flow, it generally needs to be assessed for thyroid cancer. These nodules are often hypoechoic with irregular shapes, and the ratio of their longitudinal to transverse diameter is greater than 1. They have unclear boundaries, lack a capsule, and have no halo. In typical cases, microcalcifications like sand grains can also be observed. From the above analysis, we can see that the blood flow signals in thyroid nodules are complicated and reflect the extent of the nodular pathology. These signals can help in differentiating benign from malignant nodules, but when a rich and disorganized blood flow is observed, the nodule is more likely to be malignant.

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Written by Zhang Peng
General Surgery
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Thyroid nodule surgery risks

The hazards of thyroid surgery actually refer to the risks involved in thyroid surgery. Thyroid surgery is now a common treatment method. The main risks of thyroid surgery include anesthesia on one hand, and postoperative bleeding on the other. There might be a need for a second incision for decompression. The most common complications are choking while drinking water and hoarseness of voice, mainly due to the involvement or damage to relevant nerves during the surgery. Generally, these complications resolve after a period of adjustment, and most people can recover normally.

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Written by Lin Xiang Dong
Endocrinology
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Where to do acupuncture for thyroid nodules?

Thyroid nodules do not require acupuncture treatment. The vast majority of thyroid nodules are benign, with only a small portion, about 5%, being malignant. We generally determine the treatment approach based on whether the nodule is benign or malignant. For benign nodules, we typically follow up with observation, while malignant nodules require surgical treatment and oral medication, or Iodine-131 radiotherapy. The primary evaluation for distinguishing between benign and malignant nodules relies on the results of color Doppler ultrasound and the pathology results from thyroid fine-needle aspiration.

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Written by Hu Jian Zhuo
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Are thyroid nodules serious?

The severity of thyroid nodules needs to be assessed based on their nature, size, function, and location. Generally, they can be classified into benign and malignant, with malignant nodules being thyroid cancer, which requires timely treatment. Surgical treatment is the main method for treating thyroid cancer, whereas most benign nodules do not require special handling. Regarding the size of the thyroid nodules, if the nodules are too large and compress surrounding tissues such as the trachea, esophagus, and nerves, surgical treatment is recommended. For common benign nodules, regular observation is sufficient. Functionally, some thyroid nodules may affect thyroid function, such as in Hashimoto's thyroiditis, which can present with diffuse multiple nodules, leading to either hyperthyroidism or hypothyroidism. In such cases, appropriate medication treatment is needed. From a positional perspective, ectopic growth of thyroid nodules, if located at areas like the base of the ear, pharynx, neck, esophagus, or thoracic cavity, is a rare congenital developmental anomaly. If such a nodule significantly enlarges and compresses surrounding tissues, surgical treatment is advised.