The difference between osteoarthritis and rheumatoid arthritis

Written by Cheng Bin
Orthopedics
Updated on March 22, 2025
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The so-called osteoarthritis often occurs as the patient ages, featuring localized bone hyperplasia and degenerative changes, leading to the destruction of cartilage. This results in congested and swollen synovium, manifesting as clear local symptoms of swelling and pain. Rheumatoid arthritis, on the other hand, mainly occurs due to a streptococcal infection, causing localized pain and swelling, thus forming rheumatoid arthritis. This is the difference between the two. There are also differences in treatment. Early osteoarthritis can be treated with oral non-steroidal anti-inflammatory and analgesic drugs, as well as medications that nourish the cartilage. For rheumatoid arthritis, symptomatic treatment is often necessary, and active anti-rheumatic treatment can be completely effective.

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Written by Yang Ya Meng
Rheumatology
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What medicine is taken for rheumatoid arthritis?

The medication for rheumatoid arthritis mainly falls into three categories, The first category is the choice of anti-inflammatory and pain relief medications, which mainly includes two types: non-steroidal analgesics and low doses of corticosteroids. If the patient's pain symptoms are mild, non-steroidal analgesics can be opted for. However, if the patient's pain symptoms are more severe, and there is significant liver or kidney damage, or concurrent interstitial lung disease, then the use of low doses of corticosteroids should be considered. The second and most important category is the choice of immunosuppressants, which include drugs like methotrexate and leflunomide. The third category is the treatment with biologic agents. (Medication should be administered under the guidance of a doctor)

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Written by Li Jing
Rheumatology
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What medicine is used for rheumatoid arthritis?

First, rheumatoid arthritis is an autoimmune disease and a chronic condition that cannot be cured. The primary goal of treatment is to alleviate symptoms, delay complications, improve quality of life, and reduce disability through conventional drug therapies. Treatment methods include general treatment and medication. General treatment consists of functional exercise and lifestyle considerations, such as avoiding cold water and raw, cold foods, and emphasizing the importance of exercise. Additionally, the first-line drug treatments include nonsteroidal anti-inflammatory drugs and disease-modifying antirheumatic drugs (DMARDs), with traditional DMARDs being the current preferred and anchor treatment option.

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Written by Yang Ya Meng
Rheumatology
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What causes rheumatoid arthritis?

The causes of rheumatoid arthritis are mainly classified into four categories, First, environmental factors, such as living in dark, damp conditions for a long period, may trigger the onset of rheumatoid arthritis. Second, genetic factors, the probability of developing rheumatoid arthritis significantly increases if a parent has the condition. Third, rheumatoid arthritis often relates to estrogen, thus it is more commonly seen in female patients clinically. Fourth, rheumatoid arthritis is also associated with certain infections, including some viral and bacterial infections.

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Written by Cheng Bin
Orthopedics
52sec home-news-image

The difference between osteoarthritis and rheumatoid arthritis

The so-called osteoarthritis often occurs as the patient ages, featuring localized bone hyperplasia and degenerative changes, leading to the destruction of cartilage. This results in congested and swollen synovium, manifesting as clear local symptoms of swelling and pain. Rheumatoid arthritis, on the other hand, mainly occurs due to a streptococcal infection, causing localized pain and swelling, thus forming rheumatoid arthritis. This is the difference between the two. There are also differences in treatment. Early osteoarthritis can be treated with oral non-steroidal anti-inflammatory and analgesic drugs, as well as medications that nourish the cartilage. For rheumatoid arthritis, symptomatic treatment is often necessary, and active anti-rheumatic treatment can be completely effective.

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Written by Li Jing
Rheumatology
1min 9sec home-news-image

Does rheumatoid arthritis hurt?

Firstly, rheumatoid arthritis belongs to autoimmune diseases and is a chronic condition. The main symptoms include symmetric pain in multiple joints across the body, accompanied by morning stiffness, which is why joint pain occurs and is the most common symptom. The onset is slow for most people, but some experience an acute onset, with joint mobility issues appearing within a few weeks or days. Therefore, this disease cannot be cured; it can only be managed with medications to control symptoms, delay the deformity of joints, reduce disability rates, and enhance the quality of life, which are the objectives of comprehensive treatment. It is important to avoid exposure to cold and fatigue in daily life, avoid contact with cold water, keep warm, also avoid raw and cold foods, spicy and irritating foods, and eat more light, easy-to-digest, and high-protein foods to boost the immune system.