What to check for ankylosing spondylitis?

Written by Yang Ya Meng

Rheumatology

Updated on October 22, 2024

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The examination for ankylosing spondylitis mainly includes blood tests. The main components of the blood tests are erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ANA along with CCP antibodies, and AKA antibodies, and of course, the most crucial test related to the gene - HLA-B27. Imaging exams can include the following: First, an X-ray of the pelvis, or an MRI of the sacroiliac joints. If the disease has been present for a longer time, a CT of the sacroiliac joints can be chosen. If the patient has elevated ESR and CRP, a positive B27, and lesions in the sacroiliac joints, then the diagnosis of ankylosing spondylitis can be confirmed.

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Written by Li Jing

Rheumatology

49sec

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Does ankylosing spondylitis hurt?

Ankylosing spondylitis primarily targets the axial joints, manifesting as a chronic autoimmune disease. The most common clinical symptoms include stiffness in the neck and pain in the lumbar and back regions, areas particularly associated with axial joint involvement, predominantly affecting the spine. Additionally, symptoms can also appear in areas outside of the joints, such as pain in the peripheral joints, heels, wrists, and shoulders. Moreover, some individuals may experience eye inflammation, including recurrent uveitis and corneal ulcers. While spinal pain, neck stiffness, and lumbar or back pain are the most commonly observed clinical manifestations, hip joint pain is also frequently noted.

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Written by Li Jing

Rheumatology

52sec

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How to exercise with ankylosing spondylitis?

Once diagnosed with ankylosing spondylitis, after ruling out contraindications such as hepatitis B infection and tuberculosis, it is necessary to administer standard medications to improve rheumatic conditions. At the same time, it is necessary to develop good living habits, such as abstaining from alcohol, quitting smoking, and avoiding carbonated drinks and coffee, as these can exacerbate osteoporosis. Secondly, it is important to exercise regularly; one can walk slowly, run, or swim. Swimming is the best form of exercise for patients with ankylosing spondylitis as it can enhance the coordination of limb muscles while also delaying joint wear. Thirdly, it is important to maintain good posture and sleep on a hard bed.

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Written by Li Jing

Rheumatology

1min 6sec

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Can ankylosing spondylitis cause red eyes?

Firstly, ankylosing spondylitis is a chronic autoimmune disease that primarily affects the axial joints. Its most common clinical manifestations are a stiffness in the neck or pain in the lumbar and back areas. This pain often occurs after sitting for a long time or at night, and symptoms are relieved after standing up and moving around; these are the main joint symptoms. In addition to these, there can also be extra-articular manifestations, with the most common being uveitis or iritis, which occur repeatedly. Some individuals may even develop corneal ulcers, also known in layman's terms as experiencing "red eye." These are extra-articular symptoms. Once recurrent uveitis or iritis occurs, aside from considering eye-related issues, systemic diseases must also be considered. Following the onset of this type of uveitis, the first choice of treatment is biologics.

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Written by Yang Ya Meng

Rheumatology

1min 8sec

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What medicine is used for ankylosing spondylitis?

The medication for ankylosing spondylitis mainly involves three aspects. The first is non-steroidal pain-relief medications, commonly including drugs like sustained-release diclofenac sodium tablets. The second involves drugs that control the condition, commonly using medications like sulfasalazine and thalidomide. The third, which is currently the most effective, involves treatment with biologics. Common biologics include tumor necrosis factor inhibitors. However, before using biologics, it is crucial to rigorously rule out complications such as hepatitis, tuberculosis, and tumors. Only after excluding these conditions should one consider using biologics. Patients with ankylosing spondylitis should also pay attention to appropriate functional exercises in daily life to prevent the stiffening of spinal joints. (Medications should be used under the guidance of a doctor, based on the specific situation.)

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Written by Yang Ya Meng

Rheumatology

1min 16sec

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How to relieve ankylosing spondylitis

Methods to alleviate ankylosing spondylitis are as follows: First, in terms of lifestyle: during the remission phase of ankylosing spondylitis, it is necessary to persist in long-term functional exercises to keep the spine from adhering and becoming rigid. The second and most important aspect is the long-term use of medication. The medications used to treat ankylosing spondylitis mainly include the following categories: The first category is non-steroidal anti-inflammatory drugs, commonly used ones include diclofenac sodium sustained-release tablets, celecoxib capsules, etc.; the second category includes disease-controlling medications such as sulfasalazine, thalidomide, methotrexate, and even leflunomide. Currently, the most effective medications for treating ankylosing spondylitis are biologics. However, before using biologics, it is essential to strictly rule out diseases such as hepatitis, tuberculosis, and tumors. (Medications should be used under the guidance of a doctor based on specific conditions.)