Otitis media with effusion mainly refers to a type of secretory otitis media, where there is negative pressure in the middle ear cavity and fluid accumulation occurs. Treatment usually begins with medications, lasting either one to three months or three to six months. Antibiotics, steroids, and medications that facilitate the drainage of the effusion, such as Mucosolvan, may be used. Additionally, medications that constrict the mucosal blood vessels in the nasal cavity can also be used to facilitate the function of the Eustachian tube. If medication does not relieve or cure the condition, invasive treatment methods such as tympanic membrane puncture, tympanotomy, tympanostomy tube insertion, and Eustachian tube balloon dilation can be employed.