What causes epilepsy in children?

Written by Liu Shi Xiang
Neurology
Updated on December 15, 2024
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The causes of epilepsy in children primarily include congenital factors and acquired factors. Congenital factors are mainly due to premature birth, difficult labor, umbilical cord around the neck, neonatal intracranial hemorrhage, drug factors, etc. Acquired factors mainly include brain trauma, central nervous system infections, cerebrovascular disease, intracranial tumors, and other causes. Therefore, when a child exhibits symptoms of epilepsy, it is necessary to promptly visit the department of neurology to conduct relevant examinations to determine the cause. The examination methods mainly include CT, MRI, EEG, cerebrospinal fluid analysis, etc. After identifying the cause, symptomatic treatment methods should be adopted to control the symptoms of epilepsy episodes. In clinical practice, controlling epilepsy is mainly achieved through drug treatment, with commonly used medications including carbamazepine, sodium valproate, gabapentin, etc. For some patients with refractory epilepsy, surgical treatments may also be used to control symptoms.

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Written by Tang Bo
Neurology
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What are the clinical manifestations of epilepsy?

Epilepsy is caused by abnormal discharges of brain cells, and the symptoms and clinical manifestations vary depending on the area of discharge. Main symptoms can include sudden loss of consciousness, rigidity followed by clonic convulsions, and may also involve cyanosis or purpling of the face, tongue biting, frothing at the mouth, urinary incontinence, dilated pupils, continuing for several seconds to minutes before stopping. This condition is called a generalized tonic-clonic seizure. Some patients may also experience sudden brief loss of consciousness and interruption of ongoing actions, with a blank stare and unresponsive to calls. They may perform simple automatic actions like swallowing or chewing. Generally, there is no falling, and the patient has no memory of the episode afterwards. This type of seizure is known as an absence seizure. Additionally, some may experience rigidity and clonic convulsions in one limb or a localized area, etc.

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Written by Hu Qi Feng
Pediatrics
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Care for children during epileptic seizures

During an epileptic seizure, it is crucial to control the seizure promptly by using sedative and anticonvulsant medications. While administering these drugs, it is important to closely monitor for consistent breathing. Additionally, during a seizure, it is necessary to ensure that the airway remains clear, provide oxygen, and, if required, use mechanical ventilation to maintain airway patency. Prevent biting injuries to the tongue and position the head to one side so that secretions can flow out of the corner of the mouth, preventing reflux of stomach contents and risk of choking. Protect brain function and vital organs, and prevent cerebral edema. After the seizure has stopped, long-term administration of antiepileptic drugs should be continued to prevent recurrence.

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Written by Yan Xin Liang
Pediatrics
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What is childhood epilepsy?

Epilepsy is a persistent brain disease characterized by recurrent epileptic seizures, abnormal perceptions, and associated neurological, cognitive, psychological, and social issues. An epileptic seizure refers to sudden, brief symptoms and signs caused by excessive and abnormal discharges of brain neurons. Depending on the affected brain functional areas, clinical manifestations can vary, including disturbances in consciousness, motor functions, sensory abnormalities, as well as psychiatric and autonomic nervous system dysfunctions. It is important to note that epileptic seizures and epilepsy are two distinct concepts.

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Written by Yan Xin Liang
Pediatrics
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What are the symptoms of epilepsy in children?

The typical symptoms of childhood epilepsy include sudden loss of consciousness, followed initially by tonic and then clonic convulsions, often accompanied by screaming, cyanotic facial complexion, frothing or bleeding at the mouth, dilated pupils, generally lasting 40 seconds or up to 15 minutes. The convulsive seizure stops naturally, followed by a state of coma. Of course, some affected children also display varying degrees of consciousness disorders, evident disruptions in thinking, perception, emotion, and psychomotor functions, and may show signs of conditions like somnambulism and noctambulism, among other automatisms.

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Written by Tang Bo
Neurology
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What is epilepsy?

Epilepsy is a common disease in neurology and includes many types, generally including primary epilepsy and secondary epilepsy. Primary epilepsy refers to cases where the cause is unknown, while secondary epilepsy has a clear cause. Common causes include developmental disorders of the cerebral cortex, tumors, and cerebrovascular diseases, traumatic brain injuries, and central nervous system infections, including encephalitis, meningitis. Cerebrovascular diseases such as cerebral hemorrhage and cerebral infarction can also induce epilepsy. Additionally, certain neurodegenerative diseases, such as motor neuron disease and late-stage Parkinson's disease can also trigger epileptic seizures. Patients with ischemic hypoxic encephalopathy and toxic encephalopathy may also experience epileptic seizures, and some systemic diseases may also lead to epileptic seizures.