Can pheochromocytoma be cured?

Written by Chen Yu Fei
Neurosurgery
Updated on September 08, 2024
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Currently, with the continuous advancement of surgical techniques, pheochromocytomas can be treated promptly and effectively, achieving favorable outcomes. Once a pheochromocytoma is diagnosed and accurately localized, it is advisable to promptly proceed with surgical intervention. Removing the tumor surgically usually results in effective treatment outcomes.

Before surgery, imaging studies and biochemical tests are used for the qualitative and locational diagnosis. After the nature and location of the tumor are clearly identified, the success rate of the surgery can also be increased. Pre-operative use of adrenergic receptor blockers can effectively manage the condition, leading to a reduction in blood pressure and lessening the load on the heart, thereby ensuring smooth conduct of the surgery.

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Written by Gan Jun
Endocrinology
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What size of pheochromocytoma is malignant?

The size of pheochromocytomas and the benign or malignant nature of the tumor are not greatly related. Usually, most are familial pheochromocytomas, which are most commonly bilateral, but they have a relatively high recurrence rate and are difficult to treat with fewer available treatment options. Once a pheochromocytoma is detected, it should be taken seriously and treated promptly. The presence of a tumor often indicates that it has developed to the mid and late stages, where it becomes relatively difficult to cure. Regardless of whether the tumor is large or small, it must be taken seriously and treated with care, otherwise, it may easily worsen and affect health.

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Written by Chen Yu Fei
Neurosurgery
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Is pheochromocytoma a cancer?

Pheochromocytoma is not a cancer. It is a special type of tumor tissue that usually originates from the neuroectodermal chromaffin tissue. It can secrete catecholamines. Based on the specific origins of the tumor cells, it can be divided into types such as parasympathetic, paraganglioma, sympathetic, and ganglioneuroma. Most often, it presents with long-term hypertension, which can cause damage to the heart, brain, and kidneys due to prolonged hypertension, or severe increases in blood pressure can lead to hypertensive brain hemorrhage, thereby endangering the patient's life. Early treatment is often necessary.

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Written by Li Lang Bo
Endocrinology
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What should I do if pheochromocytoma causes excessive sweating?

Patients with pheochromocytoma generally exhibit profuse sweating, which is a manifestation of sympathetic excitement. This occurs because the capillary beds throughout the body of a person with pheochromocytoma are constricted, including the sweat glands. Thus, it is easy to exhibit these symptoms of sympathetic excitement, characterized by nervousness, heavy sweating, and weight loss. So, how should this be treated? The key is to treat the cause. In the clinic, after collecting some blood history, conducting various blood tests, and performing adrenal CT scans among other imaging studies, a clear diagnosis of pheochromocytoma is made. Then, we will use some alpha receptor blockers, one to lower the blood pressure to a normal range and another to dilate the capillary beds throughout the body. After this, we proceed with the related surgical treatment. Following the surgical removal of the tumor, symptoms such as sweating will gradually be relieved.

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Written by Chen Yu Fei
Neurosurgery
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Pheochromocytoma typical manifestations

For pheochromocytoma, the term usually refers to tumors arising from the chromaffin tissue of the neural crest. Clinically, the main typical symptoms include severe hypertension, along with nausea, vomiting, intense headache, and dizziness. Additionally, it may also cause the patient to be in a continuous high metabolic state, characterized by persistent hyperglycemia, nausea, vomiting, and excessive sweating. If not treated promptly and effectively, it may pose serious threats to the patient's heart, brain, and kidneys. In severe cases, it could even be life-threatening. Surgery is commonly recommended for treatment.

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Written by Chen Yu Fei
Neurosurgery
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How is pheochromocytoma treated?

Currently, for the treatment of pheochromocytoma, it is primarily important that once diagnosed with pheochromocytoma, one should promptly visit the local hospital to arrange surgical treatment as soon as possible. By surgically removing the pheochromocytoma, this prevents the excessive secretion of catecholamines, which can lead to a hypertensive crisis in patients. Therefore, clinically, after diagnosing and locating the pheochromocytoma, receiving surgical treatment can often achieve satisfactory therapeutic outcomes. Typically, appropriate preparations must be made before surgery. Generally, prior to the operation, it is crucial to actively administer medications such as alpha-adrenergic blockers, beta-adrenergic blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors, vasodilators, and catecholamine synthesis inhibitors to effectively treat and stabilize blood pressure.