Does Hashimoto's thyroiditis cause weight loss?

Written by Chen Xie
Endocrinology
Updated on September 11, 2024
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Hashimoto's thyroiditis is an autoimmune thyroiditis where autoantibodies within the body cause the destruction of thyroid follicular cells, leading to thyroid cell failure. During the course of Hashimoto's thyroiditis, hyperthyroidism may occur. Due to the destruction of thyroid follicles by autoantibodies, a significant release of thyroid hormones into the blood occurs, resulting in a hyperthyroid state. Therefore, symptoms such as weight loss, heat intolerance, and excessive sweating which are typical of hyperthyroidism may also appear in Hashimoto's thyroiditis. However, as the disease progresses, the condition gradually leads to decreased thyroid function.

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Written by Zhang Jun Jun
Endocrinology
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Does Hashimoto's thyroiditis cause a sore throat?

Hashimoto's thyroiditis does not cause a sore throat; the type of thyroiditis that primarily causes a sore throat is subacute thyroiditis. Subacute thyroiditis is a viral infection and is a self-limiting disease. Its main clinical manifestations include sore throat, thyroid enlargement, as well as accompanying fever and elevated erythrocyte sedimentation rate. Meanwhile, Hashimoto's thyroiditis is an autoimmune disease, whose most common clinical manifestation is painless thyroid enlargement, progressing to hypothyroidism in later stages. Additionally, it involves thyroid antibodies, especially positive TPO antibodies. Because the treatments for each are different, it is important to note that Hashimoto's thyroiditis does not cause a sore throat.

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Written by Chen Xie
Endocrinology
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Can Hashimoto's thyroiditis be cured?

Hashimoto's thyroiditis is an autoimmune thyroiditis in which the body itself has autoimmune antibodies, leading to the destruction of thyroid follicular cells and the release of a large amount of thyroid hormones, possibly resulting in hyperthyroidism. Some patients may experience hyperthyroidism for years or even decades, which requires anti-hyperthyroidism treatment. However, as the disease progresses, further destruction of thyroid function may occur, resulting in hypothyroidism. For patients with Hashimoto's thyroiditis, once hypothyroidism occurs, it is usually progressive. Therefore, once hypothyroidism occurs in patients with Hashimoto's thyroiditis, lifelong replacement therapy with levothyroxine is necessary, as Hashimoto's thyroiditis cannot be completely cured, but clinical remission can be achieved through replacement therapy.

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Written by Chen Xie
Endocrinology
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Hashimoto's thyroiditis diagnostic indicators

Hashimoto's thyroiditis is a type of autoimmune thyroiditis, which can present in various phases regarding thyroid function, manifesting as hyperthyroidism, hypothyroidism, or normal thyroid function. Therefore, for patients with Hashimoto's thyroiditis, it is necessary to check thyroid function to understand its status. Since Hashimoto's thyroiditis is an autoimmune thyroiditis, the thyroid peroxidase antibodies and thyroglobulin antibodies are generally elevated. Additionally, it is necessary to perform thyroid ultrasound to assess the thyroid's condition. For some difficult-to-distinguish patients, a further examination such as a 131I uptake test can be conducted, where the uptake rate in Hashimoto's thyroiditis is reduced. Even further, a fine needle aspiration biopsy of the thyroid can be performed, where we can observe significant lymphocyte infiltration.

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Written by Chen Xie
Endocrinology
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Can Hashimoto's thyroiditis be cured?

Hashimoto's thyroiditis is an autoimmune thyroiditis where the body itself has autoantibodies that lead to the destruction of thyroid follicular cells, resulting in the failure of thyroid cells. Therefore, Hashimoto's thyroiditis can manifest as hyperthyroidism, euthyroidism, and hypothyroidism. Ultimately, Hashimoto's thyroiditis may develop into hypothyroidism. Hypothyroidism is proliferative and generally cannot be completely cured, but clinical remission can be achieved through oral administration of levothyroxine. However, Hashimoto's thyroiditis cannot be completely cured and requires lifelong replacement therapy.

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Written by Zhao Xin Lan
Endocrinology
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Hashimoto's thyroiditis symptoms

In the early stages, when the autoimmune destruction from Hashimoto's thyroiditis is not particularly severe and does not cause either hyperthyroidism or hypothyroidism, there may be no symptoms at all. As the immune response intensifies and leads to increased destruction of thyroid cells, transient thyrotoxicosis can occur, resulting in symptoms such as heat intolerance, trembling hands, and palpitations. The duration of these symptoms is related to the severity of the destruction. Generally, symptomatic relief can be achieved by administering beta-blockers. In the later stages, when the destruction of thyroid function in Hashimoto's is exacerbated, leading to hypothyroidism, symptoms such as cold intolerance, fatigue, and hair loss may occur. (Medication should be used under the guidance of a professional doctor.)