Can Hashimoto's thyroiditis be cured?

Written by Chen Xie
Endocrinology
Updated on September 05, 2024
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Hashimoto's thyroiditis is an autoimmune thyroiditis where the body itself has autoantibodies that lead to the destruction of thyroid follicular cells, resulting in the failure of thyroid cells. Therefore, Hashimoto's thyroiditis can manifest as hyperthyroidism, euthyroidism, and hypothyroidism. Ultimately, Hashimoto's thyroiditis may develop into hypothyroidism. Hypothyroidism is proliferative and generally cannot be completely cured, but clinical remission can be achieved through oral administration of levothyroxine. However, Hashimoto's thyroiditis cannot be completely cured and requires lifelong replacement therapy.

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Does Hashimoto's thyroiditis affect pregnancy?

Hashimoto's thyroiditis, it is a type of autoimmune disease. Some people might have normal thyroid function, while others may develop hypothyroidism. Therefore, if someone with Hashimoto's thyroiditis plans to become pregnant, it is essential to test thyroid function before pregnancy. For patients with Hashimoto's thyroiditis, we recommend that the thyroid-stimulating hormone (TSH) should be controlled below 2.5 mIU/L before suggesting pregnancy, as this can prevent potential impacts on the fetus's intelligence.

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Can Hashimoto's thyroiditis breastfeed?

Patients with Hashimoto's thyroiditis can breastfeed. It is important for those in a hyperthyroid phase, especially when taking anti-thyroid medications, to switch to breastfeeding-safe medications beforehand and to regularly monitor thyroid function to ensure it remains within normal limits. Patients in a hypothyroid phase should also regularly monitor their thyroid function and adjust their replacement medication dosage accordingly. Newborns should have their thyroid function and related antibodies regularly tested from birth onwards. (Please medicate under the guidance of a physician.)

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Is Hashimoto's thyroiditis severe?

Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, is a common type of autoimmune thyroid disease. Hashimoto's thyroiditis is the most common cause of hypothyroidism. If hypothyroidism caused by Hashimoto's thyroiditis is identified, long-term administration of levothyroxine can achieve good control. It is worth noting that the clinical manifestations of Hashimoto's thyroiditis are often atypical, or may coexist with other thyroid diseases, or other autoimmune diseases. Special attention needs to be paid to certain types of Hashimoto's thyroiditis. One such type is Hashitoxicosis, Hashimoto's pseudohyperthyroidism, or Hashimoto's thyroiditis accompanied by thyroid tumors, Hashimoto's encephalopathy, or Hashimoto's with proptosis. These special types require particular attention.

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Written by Chen Xie
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Hashimoto's thyroiditis diagnostic indicators

Hashimoto's thyroiditis is a type of autoimmune thyroiditis, which can present in various phases regarding thyroid function, manifesting as hyperthyroidism, hypothyroidism, or normal thyroid function. Therefore, for patients with Hashimoto's thyroiditis, it is necessary to check thyroid function to understand its status. Since Hashimoto's thyroiditis is an autoimmune thyroiditis, the thyroid peroxidase antibodies and thyroglobulin antibodies are generally elevated. Additionally, it is necessary to perform thyroid ultrasound to assess the thyroid's condition. For some difficult-to-distinguish patients, a further examination such as a 131I uptake test can be conducted, where the uptake rate in Hashimoto's thyroiditis is reduced. Even further, a fine needle aspiration biopsy of the thyroid can be performed, where we can observe significant lymphocyte infiltration.

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How is Hashimoto's thyroiditis treated?

After being diagnosed with Hashimoto's thyroiditis, treatment decisions should be made based on the size of the thyroid and the presence of symptoms. If the thyroid is relatively small and there are no significant compression symptoms, it is possible to follow up and observe without treatment. If the thyroid is significantly enlarged and there are compression symptoms, thyroid hormone preparations can be used to reduce thyroid swelling. If there is hypothyroidism, it is necessary to use thyroid hormone or levothyroxine for supplementary replacement therapy. In cases of Hashimoto's thyroiditis with hyperthyroidism, short-term treatment should follow the treatment for Graves' disease, using antithyroid treatments such as thioamides or thioureas. (Medications should be used under the guidance of a physician, and self-medication without guidance is strongly discouraged.)