Regarding the causes of hyperlipidemia, it is generally categorized into primary and secondary types based on the causes. Primary hyperlipidemia is mainly due to genetic defects, such as certain familial hypercholesterolemia and familial mixed dyslipidemia, which are often caused by genetic defects. Secondary hyperlipidemia generally involves some acquired factors, including, for example, high fat content in the diet, which is a common cause of lipid abnormalities. Additionally, obesity can lead to increased plasma cholesterol. Long-term heavy drinking can also increase triglycerides in the blood. Smoking can also cause some drugs, such as estrogen, to raise blood triglycerides. Some glucocorticoids can also increase the synthesis of low-density lipoproteins, and so on. Other causes include diseases such as diabetes, kidney disease, estrogen deficiency, hypothyroidism, systemic lupus erythematosus, glycogen storage diseases, and certain types of malnutrition, which can also lead to secondary lipid abnormalities. Therefore, the causes of hyperlipidemia are multifaceted.