Patients with nasopharyngeal carcinoma may exhibit fever in a clinical setting. This fever can partially be due to the worsening of the carcinoma itself. However, not all cases are due to progression of the disease; some are caused by infections and other factors. For example, after receiving anti-tumor treatments such as radiotherapy and chemotherapy, patients with nasopharyngeal carcinoma may experience a decrease in white blood cells, making them highly susceptible to infections, which can then manifest as fever. Additionally, patients with nasopharyngeal carcinoma may have weakened immune systems, making them prone to infections and fevers. As the nasopharyngeal carcinoma progresses, it can release abnormal hormones, forming endogenous fever-inducing agents, leading to clinical manifestations of fever. Generally, this type of fever is referred to as tumor fever, which is often related to the progression of the disease. Tumor fever typically requires anti-tumor treatment for effective relief.