How to check for nasopharyngeal carcinoma?

Written by Deng Bang Yu
Otolaryngology
Updated on August 31, 2024
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Nasopharyngeal carcinoma is a malignant tumor in the nasal area, clinically mainly squamous cell carcinoma. The incidence of nasopharyngeal carcinoma is relatively high in southern regions of our country. Clinically, the primary treatment is radiotherapy. For diagnosis, the first general step involves using an electronic nasopharyngoscope to examine the nasopharyngeal area for suspicious conditions. Further imaging studies can also be conducted, such as CT scans and MRI scans of the nasopharyngeal area. Through these examinations, if a neoplasm in the nasal area is essentially identified and suspected to be nasopharyngeal carcinoma, an endoscopic examination is conducted where forceps are used to clip tissue for a pathological biopsy. The pathological biopsy determines whether it is definitively nasopharyngeal carcinoma and identifies the type of cancer cells, thus guiding clinical treatment.

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Nasopharyngeal carcinoma brain metastasis symptoms

Nasopharyngeal carcinoma is a relatively common type of head and neck malignant tumor. If brain metastasis from nasopharyngeal carcinoma occurs, it may cause related clinical symptoms. Common symptoms include headaches, dizziness, decreased vision, and visual field defects. Additionally, some patients may experience fever, but there is significant variability in clinical symptoms among individuals. In such cases, it is necessary to visit departments such as otolaryngology, neurology, and oncology. A head MRI can be conducted to assess the extent of the condition. Generally, options like radiation therapy and chemotherapy are available. With timely treatment, some patients can still achieve a relatively long survival time.

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Symptoms of nasopharyngeal carcinoma

Nasopharyngeal carcinoma is a malignant tumor that occurs in the nasopharyngeal area. Typically, nasopharyngeal carcinoma often occurs at the top of the nasopharynx and on the lateral walls of the rhinitis. In the early stages, patients may experience nasal congestion, a runny nose, and upon waking, they might have yellow or bloody discharge. In severe cases, the patient may also experience symptoms such as hearing loss, tinnitus, and ear fullness. If a patient exhibits the aforementioned symptoms, they should first visit a hospital for an electronic nasopharyngoscopy. This can reveal the presence of cauliflower-like neoplasms or ulcers in any part of the nasopharynx. If such findings are observed, a local pathology biopsy is needed. If it is confirmed to be a malignant tumor of the nasopharynx, relevant radiotherapy and chemotherapy treatments are required. Additionally, the patient should also undergo regular systemic examinations to check for distant metastases.

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What tests are done for nasopharyngeal carcinoma?

The examination items for nasopharyngeal carcinoma are mainly divided into three types. The first type is imaging examinations, the second type is blood tests, and the third type is endoscopic pathological biopsy. Imaging examinations mainly involve CT or MRI of the nasopharynx and the whole body. If necessary, PET-CT may also be considered to clarify the extent of the condition and determine the presence of neck or distant metastases, which is helpful for diagnosis and adjuvant therapy. The second type involves blood tests, mainly including general biochemical blood tests and virus detection, which can assess the basic functional status of the body. The third type is the endoscopic pathological biopsy, which involves performing a pathological biopsy under nasal endoscopy, primarily to confirm the diagnosis and observe the extent of the lesion in the nasopharynx.

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Do people with nasopharyngeal carcinoma lose weight?

Some patients with nasopharyngeal carcinoma may experience weight loss, but individual differences exist. This is somewhat related to the condition itself as well as to the individual's resistance and their baseline physical fitness. If the condition is detected early and the clinical symptoms are not particularly obvious, most patients will not show significant weight loss, and many people may not have noticeable symptoms. If the condition is severe, and diet and nutrition are not properly managed in a timely manner, patients may experience weight loss, especially in advanced stages of the illness. This can result in a cachectic-like state, which poses greater challenges for treatment. It is necessary to seek medical attention promptly, assess the physical condition, and consider the need for radiotherapy and chemotherapy.

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Nasopharyngeal carcinoma clinical manifestations

Nasopharyngeal carcinoma is the most common malignant tumor in the nasopharyngeal area, and clinically, it is primarily squamous cell carcinoma. The incidence of nasopharyngeal carcinoma is particularly high in the southern regions of China, especially in Guangdong. Initially, nasopharyngeal carcinoma manifests locally as a tumorous mass in the nasopharyngeal area, often with ulceration on the surface. This can lead to the presence of blood in nasal mucus, known as bloody nasal discharge. As the disease progresses, there can be swelling of the cervical lymph nodes, primarily involving the upper deep cervical lymph nodes, with about 60% of patients experiencing this type of lymph node enlargement. As the tumor enlarges, it may block the nasal passage, leading to persistent nasal congestion. The tumor's pressure on the Eustachian tube can cause symptoms of secretory otitis media. Furthermore, damage to the skull base by the tumor can lead to severe headaches. As a malignant tumor, the cancer can cause systemic symptoms such as malnutrition and cachexia. In advanced stages, metastatic symptoms may appear, such as bone and liver metastases, affecting these vital organs.