Causes of Nasopharyngeal Carcinoma

Written by Xu Qing Tian
Otolaryngology
Updated on January 27, 2025
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Nasopharyngeal carcinoma is a common malignant tumor in otolaryngology, ranking first in incidence among otolaryngological diseases. The main causes are often associated with the patient's long-term chronic inflammation in the nasal cavity, smoking, drinking, and other bad habits. For patients with nasal cancer, it is mainly about avoiding exposure to irritating gases and abstaining from smoking and drinking in daily life to prevent the occurrence of nasal cancer. Additionally, we can use electronic nasopharyngoscopy, electronic laryngoscopy, and blood system EB virus tests, among others, to exclude nasopharyngeal carcinoma. If local tumor proliferation is found in the pharyngeal recess or nasopharynx, biopsy forceps can be used to remove the patient's tumor for pathological examination and diagnosis.

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Can nasopharyngeal cancer be cured?

Nasopharyngeal carcinoma is a relatively common type of head and neck malignant tumor. Currently, radiation therapy is commonly used for treatment. Depending on the severity of the patient's condition, some patients may also need to combine chemotherapy. The specific treatment effectiveness varies from individual to individual, and some patients can achieve clinical cure. For early-stage nasopharyngeal carcinoma, the treatment effectiveness is relatively good, and the clinical cure rate is comparatively high. For mid to late-stage nasopharyngeal carcinoma, the treatment becomes more challenging, and the treatment effectiveness is relatively poorer. After treatment, regular check-ups are required to monitor the recovery of the condition. If no recurrence or distant metastasis is found five years after treatment, the patient is considered clinically cured.

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Can late-stage nasopharyngeal carcinoma be cured?

Nasopharyngeal cancer is a malignant tumor located in the nasopharynx. Late-stage nasopharyngeal cancer refers to stages three and four, particularly stage four, where the patient experiences destruction of adjacent tissue structures and metastasis to distant organs. In such cases, clinical treatment generally involves symptomatic management or palliative care, aimed at improving the patient's quality of life and alleviating suffering. Whether nasopharyngeal cancer, especially in its late stages, can be cured is highly uncertain; its prognosis is very poor, and no one can definitively answer if it can be cured. However, the chances of cure are extremely slim, and the main approach is to provide palliative treatments.

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Is nasopharyngeal carcinoma prone to metastasis?

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck area and is prone to metastasis. The most common metastasis site is the cervical lymph nodes. Some patients are diagnosed with nasopharyngeal carcinoma only after the discovery of cervical lymph node metastatic cancer. Additionally, some patients may experience intracranial metastasis or bone metastasis. Generally speaking, for patients with nasopharyngeal carcinoma, it is crucial to achieve early detection, early diagnosis, and early treatment. After treatment, long-term regular follow-up is necessary to help determine the presence of metastasis. Moreover, if metastasis is confirmed, comprehensive treatment should be combined.

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Can stage IV nasopharyngeal cancer be cured?

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck region. If it is stage IV nasopharyngeal carcinoma, achieving clinical cure is very difficult; only a small portion of patients have the chance to achieve clinical cure, as stage IV nasopharyngeal carcinoma is considered advanced. The current common treatments are a combination of radiotherapy and chemotherapy. During the treatment process, regular reviews are necessary to observe the effects of the treatment. Some patients respond well to the treatment, and the tumor can be completely eliminated after treatment; however, for some patients, the treatment can only control the rapid growth of the tumor, not completely eradicate it. Even if the tumor completely subsides, there might still be a chance of local recurrence or distant metastasis after the treatment ends.

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Where is the best place to treat nasopharyngeal carcinoma?

Nasopharyngeal carcinoma currently mainly considers radiation therapy and chemotherapy, with radiation therapy as the primary treatment. It requires staging and typing based on different ranges of lesions and pathological biopsy types. After determining the stage and type, further radiation and chemotherapy plans can be established. At present, radiation therapy is the most important. Most patients need concurrent chemotherapy or adjuvant chemotherapy and require regular follow-ups. For some patients with cervical lymph node metastasis or recurrence of nasopharyngeal carcinoma after radiation therapy, who cannot undergo radiation or chemotherapy again or for whom radiation and chemotherapy have failed, surgery may be considered. However, surgery is generally not the first choice and its effectiveness is not particularly certain.